Open Access DOI:10.23937/2474-3658/1510250

A Comparative Study of Acinetobacter Infections in COVID and Non-COVID Patients

Rayeesa Faheem Syed, MBBS, MS, Sadhana Yelamanchili, MD, FRCPath and Srinivas Thati, MBBS, MS, MRCS, FRCS

Article Type: Case Series Study | First Published: February 10, 2022

Acinetobacter species are associated with high mortality, with A. baumannii being associated with a significant number of hospitals acquired infections worldwide. Multidrug resistance makes it challenging to control or treat these infections. Aim of this study is to evaluate the risk factors and compare the clinical outcomes of Acinetobacter infections in a tertiary care hospital, in COVID and non COVID patients. A retrospective observational study was conducted. A list of all cases with positiv...

 Open Access DOI:10.23937/2474-1353/1510135

Measuring Independent and Controlled Effects of Age at First Marriage and Age at First Birth on Completed Family Size among Women Aged 45-49 in Zambia

Nkuye Moyo, Tina Nanyangwe-Moyo, Xiaochun Qiao, Jilei Wu and Xiaoying Zheng

Article Type: Original Research | First Published: February 09, 2022

The link between age at marriage and first birth in explaining completed family size is not always direct, due to heterogeneity in circumstances, that compel individual women to marry or initiate childbearing at a particular age. We analyzed data for 1020 women aged 45- 49 in 2014 of the 1965-1969 birth cohort from the 2013-14 Zambia Demographic and Health Survey (ZDHS). We fitted a bivariate and multivariate multinomial logistic regression to establish the relationship between a mother’s age ...

 Open Access DOI:10.23937/2469-5807/1510123

High Expression of RAGE and HMGB1 in Lung Tissue of Decedents with COVID-19 and Diabetes

Yared Tekabe, Anjali Saqi, Geping Zhang, Monica Goldklang and Lynne L Johnson

Article Type: Original Research | First Published: February 17, 2022

Serum biomarker studies on patients with severe COVID-19 lung disease indicate that increased ligands for Receptor for Advanced Glycation End-products (RAGE) and diabetes are risk factors for severe acute respiratory distress syndrome (ARDS). To investigate in situ RAGE expression in coronavirus disease-19 (COVID-19) ARDS, we obtained lung tissue from autopsies performed on COVID-19 decedents with clinical ARDS and corresponding pathology showing diffuse alveolar damage (DAD) both with and witho...

 Open Access DOI:10.23937/2643-4563/1710036

Bladder Neuroendocrine Carcinoma: About Five Cases and Review of the Literature

Maryam Zaouit, Farida Marnissi, Hassan Jouhadi, Nadia Benchekroun, Asma Elkbir, Souha Sahraoui and Abdellatif Benider

Article Type: Case series | First Published: February 07, 2022

This is a retrospective descriptive study of five cases of neuroendocrine carcinoma of the bladder collected at the Mohammed VI Center, between January 2017 and December 2020. The diagnosis was confirmed by immunohistochemical study. The median age is 61 years (extremes: 36-73 years), all patients are male. The average delay of consultation is 7 months (extremes: 2-12 months). Chronic smoking was found in three patients. Hematuria was the cardinal sign in 4 cases. Irritative urinary disorders su...

 Open Access DOI:10.23937/2474-3674/1510140

Transient Asystole Linked to Dexmedetomidine Infusion

Noelle Provenzano, DO, Olivia Johnson, PharmD, BCCCP, Aaron Brophy, DO and Jaber Monla-Hassan, MD

Article Type: Case Report | First Published: February 17, 2022

Five adult medical, critically ill patients developed bradycardia leading to asystole while receiving dexmedetomidine infusion. This is a case series of five adult patients obtained from the medical intensive care unit in a community teaching hospital between May 2019 through August 2020. These patients were each receiving dexmedetomidine infusion while on invasive mechanical ventilation leading to periods of asystole that resolved after stopping dexmedetomidine infusion in all five patients. Th...

 Open Access DOI:10.23937/2474-3674/1510139

Hyperglycemic Crisis: A Serious Complication of Unknown Type II Diabetes Mellitus in Adolescent

Elisa, MD and Pratiwi Woro R, MD PhD

Article Type: Case Report | First Published: February 11, 2022

Hyperglycemic crisis is life threatening condition in diabetic patients. Traditionally, diabetic ketoacidosis (DKA) has been associated with decompensated type 1 diabetes (T1D) and Hyperosmolar Hyperglycemic State (HHS) became a hallmark of type 2 diabetes (T2D). However, DKA is increasingly being reported in patients with T2D. We reported a case of DKA with some features of HHS, as an initial presentation, in a boy with unknown T2D at young age. Prompt diagnosis and acute critical care approach...

 Open Access DOI:10.23937/2474-3674/1510138

Emergency Medical Rescue Services in Dhaka City, Bangladesh: A Situational Analysis and Needs Assessments

Mohammad Mojahidul Hossain, Axel Kroeger, Kamelia Pervin, George Norwood, Be-Nazir Ahmed, Manzur Kadir Ahmed and Hans-Joerg Busch

Article Type: Original Article | First Published: February 10, 2022

Deaths and disabilities due to the lack of proper Emergency Medical Rescue Services (EMRS) is a global public health concern, also in Dhaka city, Bangladesh. The study aimed at contributing to improve the EMRS in Dhaka city by assessing and identifying major shortcomings with possible solutions. The study was conducted in July/August 2017, after analyzing medical and relevant records, a one week observational study was conducted in 4 purposively selected hospitals in Dhaka city. The Mode of tran...

 Open Access DOI:10.23937/2378-2951/1410248

Mitral Regurgitation in Hypertrophic Cardiomyopathy: A Narrative Review of Mechanism and Current Management

Ashraf M Anwar, MD, PhD, FESC

Article Type: Review Article | First Published: February 10, 2022

Significant mitral regurgitation (MR) is frequent in patients with hypertrophic cardiomyopathy (HCM) either obstructive or non-obstructive. Many studies described that significant MR is associated with poor long-term outcome of HCM patients, which indicate the importance of an adequate MR assessment including detailed evaluation of the mitral valve (MV) anatomy. Mitral malformations have been identified in HCM at all levels. They occur in the MV leaflets with a wide array of malformations of the...

 Open Access DOI:10.23937/2690-3164/1710013

Surgical Management of Coronary Artery Disease in Al-Thawrah Hospital Sana’a, Yemen 2018 To 2020

Nabeel Al-Mudhwahi, MD,PhD and Abeer Shaia'a Naji Sa'adan, MD

Article Type: Original Article | First Published: February 10, 2022

The incidence of ischemic heart disease (IHD) is increasing worldwide. The number of patients with IHD with or without interventions coming for non-cardiac surgical procedures are increasing. These patients have an increased risk of myocardial ischemia, myocardial infarction (MI), conduction disturbances, morbidity, and mortality during the perioperative period. This study aimed to assess the surgical management of ischemic heart disease patients in Al- Thawrah hospital Sana’a Yemen from 2018 ...

 Open Access DOI:10.23937/2643-4512/1710073

A Prescription Refill Intervention to Improve Patient and Physician Satisfaction

Daniel P. Dunham, MD, MPH and Christopher Cheney, MHA

Article Type: Original Article | First Published: February 17, 2022

Physician burnout has been increasing over the past decades. This phenomenon is found throughout the world and is multifactorial. Some causes are easily identified and treatable. Of the remedial causes, improved practice efficiency is one that deserves attention. Time spent directly with patients will always be a core component of health care. Provider time spent away from direct patient care is often a cause of frustration and should be minimized. High quality communication between patients and...