Open Access DOI:10.23937/2690-263X/1710013

In Drugs of Abuse Sample Validity Testing, Which Assay is Telling the Truth? A Comparison Between Sample Check Assay and Oxidant Assay

Ashraf Mina, Leah McNeice, Shanmugam Banukumar and Santiago Vazquez

Article Type: Research Article | First Published: April 14, 2021

Sample adulteration and synthetic or fake urines are challenges laboratories need to address when testing for Drugs of Abuse. Creatinine, pH, Specific Gravity (SG) assays are commonly tested for sample validity, but these assays are not sufficient to address sample adulteration and synthetic urines. Sample Check and Oxidant assays were evaluated in a study to examine which assay would add more value to sample validity testing. We analysed 612 urine samples using creatinine assay, Sample Check as...

 Open Access DOI:10.23937/2572-407X.1510030

Clinical, Endocrinological and Histopathological Evaluation of Patients with Adrenal Incidentaloma - A Single-Center and Retrospective Study Including 320 Patients

Ahmet GORGEL, Devrim DOLEK CETİNKAYA, Fusun SALGUR, Mustafa DEMIRPENCE, Husnu YILMAZ and Mitat BAHCECİ

Article Type: Research Article | First Published: April 14, 2022

The aim of our study is to evaluate the patients with adrenal incidentaloma in terms of clinical and endocrinological features and, to determine whether a correlation between the malignancy and preoperative tumor size via analyzing of the histopathological results of the masses. This study was performed on 320 patients (86 males, 234 females) with adrenal incidentaloma who visited our clinic during a period of 3 years. Chi-square test was used to categorize the patients according to their hormon...

 Open Access DOI:10.23937/2643-4512/1710072

SARS-CoV-2 Transmission, before Delta Variant became Dominant, of Asymptomatic Primary Cases in Families. Asymptomatic Primary Cases More Frequently Give Origin to Asymptomatic Secondary Cases

Jose Luis Turabian

Article Type: Research Article | First Published: January 29, 2022

The kinetics of viral shedding of asymptomatic COVID-19 in families is not well understood. To study the characteristics of secondary cases in families, after the appearance of a primary asymptomatic case vs. symptomatic. An observational, longitudinal and retrospective study of families, in which there were at least two polymerase chain reaction (PCR) confirmed COVID-19 cases (one primary case or index and at least one secondary case), was conducted from March 15 to December 25, 2020, in a gene...

 Open Access DOI:10.23937/2469-5777/1510097

Complex Sacral Fracture and Associated Soft Tissue Injuries: A Case of Multidisciplinary Management in Polytrauma

Italia Odierna, MD, Carlo B Bussemi, MD, Fulvio Scarpato, MD, Daniele Scarano, MD, Iolanda Esposito, MD, Emanuela Apicella, MD, Salvatore Guerriero, MD and Vincenzo Stridacchio, MD

Article Type: Case Report | First Published: April 08, 2022

Treatment of high-energy trauma of the lumbosacral region is a challenging entity for clinicians. They are complex and often associated with other injuries such as active bleeding and substantial soft tissue injuries. Therefore, good wound healing is reliant on multiple local and systemic factors. Only a multidisciplinary approach between the trauma team and subspecialists will dictate the most appropriate management for these patients, and recent data has shown that best outcomes are obtained w...

 Open Access DOI:10.23937/2377-9004/1410222

Vaginal Dysbiosis Management and the Efficacy of a Non- Hormonal Hyaluronic Acid-Based Vaginal Gel (Palomacare®) as an Adjuvant Treatment: The Palomascopia Survey

Fernando Losa, Santiago Palacios, Silvia P González Rodríguez, Laura Baquedano, Danial Khorsandi and María José Muñoz

Article Type: Brief Report | First Published: March 31, 2022

To understand the diagnosis and treatment strategies for vaginal dysbiosis (VD), and the efficacy of Palomacare® vaginal gel as an adjuvant treatment and for relapse prevention. The Palomascopia study was a digital survey conducted from January to March 2021. The data was analyzed once collected. In Spain, 61% of gynecologists perform a vaginal culture to diagnose VD. To treat bacterial vaginosis 67% of gynecologists, prescribe topical antibiotics and 17% recommend prebiotics, meanwhile 71% of ...

 Open Access DOI:10.23937/2643-4474/1710104

A Rare Cause of Increased Intracranial Pressure and Papilloedema: An Intradiploic Epidermoid Cyst

George Bonanos, Shahid Kahn, Peter Kralt and Nitin Mukerji

Article Type: Case Report | First Published: April 15, 2022

We present a rare cause of increased Intracranial Pressure (ICP) and papilloedema in a male adult. The presenting symptoms of blurred vision and headaches were investigated with brain imaging which revealed an intradiploic epidermoid cyst, extending intracranially compressing the torcular Herophilli. Presence of papilloedema should trigger cranial imaging to look for causes of raised intracranial pressure. Obstruction of the venous sinuses flow is a recognized cause of raised intracranial pressu...

 Open Access DOI:10.23937/2643-4474/1710103

Prenatally Diagnosed Suprasellar Arachnoid Cyst: When to Treat?

Baticam NS, Alloy E, Rolland A, Fuchs F and Roujeau T

Article Type: Case Report | First Published: April 08, 2022

Suprasellar Arachnoid Cysts (SAC) are rare heterogenous entities that can be diagnosed and treated prenatally or postnatally, depending on their type and symptoms. We report a case of a prenatally diagnosed suprasellar arachnoid cyst treated postnatally. The cyst was diagnosed on a routine ultrasound at 22 weeks of gestation. It was a very large cyst in the prepontine region, compressing the brain stem and the 4th ventricle, causing a ventriculomegaly. The cyst was rapidly evolutive in the ultra...

 Open Access DOI:10.23937/2469-5726/1510093

A Case of Extensive Hand Extensors Tendon Rupture Due to Pseudo-rheumatoid Arthritis - A Great Mimicker of Rheumatoid Arthritis

Young Min Cho, MD, Louise Jones, PhD and Brent Flickinger, MD

Article Type: Case Report | First Published: October 07, 2022

Calcium pyrophosphate deposition (CPPD) disease is caused by calcium pyrophosphate (CPP) crystal deposition in the fibrocartilage. It usually presents as monoarticular deposition but can deposit in multiple joints presenting as chronic polyarticular disease mimicking rheumatoid arthritis (RA), known as pseudo-rheumatoid arthritis, making it very challenging for the correct diagnosis. We are presenting a case of a 64-year-old female presented with chronic polyarticular disease refractory to disea...

 Open Access DOI:10.23937/2572-4193.1510119

Chronic Rhinosinusitis and Coronary Heart Disease: A Population-Based Study

Chiung-Chang Lin, MD, Jen-Kai Weng, MD, Tsung-Han Yang, MD, Cheng-Ming Luo and Yung-An Tsou

Article Type: Research Article | First Published: April 07, 2022

Chronic rhinosinusitis (CRS) is a well-known heterogeneous disorder due to its potentially infectious status along with long-term inflammation of the nose, paranasal sinuses, and lining of the nasal passages, which lasts for 12 consecutive weeks or longer. Although the definite pathophysiological mechanism is not clear, recent studies have postulated bacterial infections with biofilm or fungal colonization as the pathophysiological mechanisms. Coronary heart disease (CHD) is a critical public he...

 Open Access DOI:10.23937/2572-3278/1510061

Fistuloclysis and Chyme Reinfusion: Novel Feeding in a Rare Case with Multiple Fistulae following Surgery

Siong Pang, Angela Vivanti, Mark Landy and Bradley Morris

Article Type: Case Report | First Published: April 07, 2022

Fistuloclysis and chyme reinfusion is a complex method of feeding that has not been widely used at our tertiary hospital. This case study of this 62-year-old male admitted with post-operative complications to our facility for consideration of surgical repair. This case study aims to describe the challenges faced by the multidisciplinary team when implementing fistuloclysis and chyme reinfusion while attempting to achieve nutritional goals and achieve positive patient outcomes. We also describe s...