Open Access DOI:10.23937/2378-3656/1410404
Merkel Cell Carcinoma of the Upper Eyelid: A Case Report and Review of the Literature
K Coulibaly, S Anajar, E Othman, Amal Hajjij and F Slimani
Article Type: Case Report | First Published: September 30, 2022
Merkel cell carcinoma of the upper eyelid is a rare and aggressive tumor. It develops from Merkel cells present in areas with glabrous skin. It touches females more than males. A 42 years old female patient presented with a nodular painless and purplish lesion of the left upper eyelid. The diagnosis of Merkel cell carcinoma was made on histopathological examination and immunohistochemical analysis....
Open Access DOI:10.23937/2378-3672/1410065
Evaluation of Some Inflammatory Cytokines Levels as A Marker for Diabetes
Mabrouk A Abo-Zaid, Soha S Mohammed and Ahmed H Ismail
Article Type: Research Article | First Published: September 05, 2022
From the different causes of death diabetes has an advanced rank in the first 10. So the aim of this study was to relate between some pro-inflammatory cytokines (TNF-α, IL-6, and TGF-β1) and infection with diabetes as biomarkers for infection. Forty male Wister albino Streptozotocin (STZ) induced diabetic rats were used as a model for estimation of the related cytokines. The animals were divided in two groups, the first group was given a placebo, whereas the second was given Streptozotocin at ...
Open Access DOI:10.23937/2572-3286.1510078
Non Proteinuric Diabetic Kidney Disease: A Narrative Review
Vinay Srinivasa
Article Type: Brief Report | First Published: September 16, 2022
Albuminuria followed by a decline in glomerular filtration rate has been described to be the classical phenotype of diabetic kidney disease (DKD). A new phenotype, non albuminuric diabetic kidney disease (NADKD), has recently been observed in patients with decreased renal function and a urine albumin excretion rate < 30 mg in 24 hours or a urine albumin creatinine ratio of < 30 mg/g....
Open Access DOI:10.23937/2469-5718/1510232
Body Composition Changes in College Basketball Players Over Summer Training
Shaun Kuo, Aston Dommel and R Drew Sayer
Article Type: Original Article | First Published: September 17, 2022
Body composition is an important determinant of athletic performance that is directly influenced by training and detraining. Collegiate athletes experience substantial variability in training intensity during a season, but little research has been conducted to track changes in body composition across periods of intense training and breaks from structured sport-related activities....
Open Access DOI:10.23937/2643-4563/1710045
Leiomyosarcoma of the Inferior Vena Cava Presenting as a Renal Mass: A Case Report
Hind Saad Al-Otaibi, Mohammed Hassan Ahmed, Ghaidaa Naser AbdulRazak, David Bakiratharajan, Talal Abdulla Alanzi and Tarek Essam Eldin Ahmed
Article Type: Case Report | First Published: August 29, 2022
Leiomyosarcomas (LMS) are rare tumors associated with poor outcomes. Treatment of the condition is challenging due to limited cases in the literature. Here, we present a case of a 46-year-old male who presented with left lower limb deep vein thrombosis, with an ultrasound scan revealing a right renal mass. MRI demonstrated a large, well-circumscribed lesion engulfing the middle and lower right renal poles associated with an invasion of the related part of the inferior vena cava (IVC), right rena...
Open Access DOI:10.23937/2643-4563/1710044
Carcinoma Breast: Correlation of Immunohistohemical Expression of Cyclin D1 and Its Correlation with Clinicopathological Parameters in Indian Patients at Tertiary Care Hospital
Ritu Mehta and Rashmi Yadav
Article Type: Original Article | First Published: August 29, 2022
To study the prevalence of Cyclin D1 expression and its correlation with other clinicopathological parameters like age, tumor size, lymph node status, MBR grade, and expression of other immunohistochemical markers like ER, PR, Her 2 - neu, and Ki67. Thirty cases diagnosed were included in the study. All the cases were subjected to routine histopathology along with IHC for ER PR, Her2-neu, Ki67, and Cyclin D1....
Open Access DOI:10.23937/2643-4563/1710043
Feasibility and Value of Salivary Cortisol Sampling to Reflect Distress in Head and Neck Cancer Patients Undergoing Chemoradiation: A Proof-of-Concept Study
Karishma Chhabria, MPH, PhD, Mark Bonnen, MD, Joshua Asper, PA-C, Giselle D Carnaby, MPH, PhD
Article Type: Systematic Review | First Published: September 12, 2022
Head and neck cancer (HNC) patients undergoing chemo/radiation commonly experience severe and persistent distress associated with treatment related fear and physical side effects such as xerostomia, dysphagia, and dryness of mouth. Cortisol, a stress sensitive hormone, can be easily measured in saliva to reflect biobehavioral responses to such stressors. Unfortunately, it has not been used in this population due to concerns associated with chemoradiation (C/RT) related xerostomia....
Open Access DOI:10.23937/2643-4474/1710119
Hirayama Disease: A Case Report and Review of Literature
Dr. Anurag Chandrakant Dandekar and Dr. Nirav A Mehta
Article Type: Case Report | First Published: September 15, 2022
Hirayama disease is a rare disorder seen in young patients in their second or third decade of life with slowly progressive self-limiting distal upper limb muscle weakness with seldom symmetrical involvement. It is a peculiar anterior horn cell disease that is managed conservatively with limited surgical options available as per literature....
Open Access DOI:10.23937/2474-3658/1510277
Inflammatory Markers and Hematologic Indices in the Prediction of Severity of COVID-19: A Single Center Study in Southern Philippines
Meccar Moniem H Elino, MD, Michael John P Pecaoco, MD, Kathryn U Roa, MD, MPH, FPCP, FPSMID, CSPSH and Jessie F Orcasitas, MD, FPCP, FPCCP
Article Type: Research Article | First Published: September 14, 2022
Various diagnostic tests across COVID-19 literatures were employed as surrogate markers in COVID-19, wherein interleukin-6 (IL-6) - gauge for cytokine storm or impending severity - is not readily available. This study determined the clinical value of inflammatory markers and hematologic indices as warning indicators in the prediction of severity of COVID-19 infection. Cut-off values were also determined....