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 Case Report 


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Published Date
May 12, 2017

Vol. 4, Issue 2

The Hepatic Hydrothorax

Aujayeb A and Miller J

Corresponding author: Aujayeb A, Respiratory Consultants, North Tyneside General Hospital, North Shields, United Kingdom

A 74-year-old with burnt out autoimmune hepatitis, portal hypertension with thrombocytopenia, oesophageal varices and previous hepatic encephalopathy has presented with a recurrence of a left sided pleural effusion. She was very breathless at rest and therapeutic aspiration of 1.1 litres of straw coloured fluid has good symptomatic benefit.

Citation: Aujayeb A, Miller J (2017) The Hepatic Hydrothorax. Int J Respir Pulm Med 4:070. doi.org/10.23937/2378-3516/1410070



 Case Report 


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Published Date
March 09, 2017

Vol. 4, Issue 2

A Rare Case of Simultaneously Occurring Pulmonary Fungal Infections

William Li, Bhaskara Madhira and Michael Kosters

Corresponding author: Bhaskara Madhira, MD, SUNY Upstate Medical University, 750 E. Adams St, Syracuse, NY 13210, USA, Tel: 314.691.8862, E-mail: Reddymab@upstate.edu

Endemic infections produce a spectrum of illness ranging from being subclinical to severe progressive disseminated diseases with Immuno compromised individuals being increased risk. In those with an apparently non-improving infection, a simultaneously occurring second infectious source should be considered.

Citation: Li W, Madhira B, Kosters M (2017) A Rare Case of Simultaneously Occurring Pulmonary Fungal Infections. Int J Respir Pulm Med 4:068. 10.23937/2378-3516/1410068.



 Research Article 


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Published Date
February 20, 2017

Vol. 4, Issue 1

A Single Center Review of Pleural Fluid Samples

C Walker, J Mackenzie, J Aust, J Port, D Cooper, S Parker, S Bourke, J Miller, M Weatherhead and A Aujayeb

Corresponding author: Dr. Avinash Aujayeb, Respiratory Consultants, North Tyneside General Hospital, Northumbria Healthcare NHS Foundation Trust, Rake Lane, North Shields, Newcastle, England

All pleural aspirations done between January 1st 2014 and December 31st 2015 were analyzed for fluid biochemistry, microbe, cytology and final diagnoses (n = 264). Light's criteria were applied wherever possible. The fluid biochemistry, microbiology and cytology results were assimilated from the local electronic results system. The patient diagnosis was taken from clinic letters electronically uploaded to another system called SingleView. Local governance approval was sought and obtained.

Citation: Walker C, Mackenzie J, Aust J, Port J, Cooper D, et al. (2017) A Single Center Review of Pleural Fluid Samples. Int J Respir Pulm Med 4:067.



 Case Report 


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Published Date
February 10, 2017

Vol. 4, Issue 1

Seromucinous Hamartoma Presenting as an Obstructive Endobronchial Mass

Guang-Qian Xiao and Sapna Patel

Corresponding author: Dr. Guang-Qian Xiao, Department of Pathology, Keck Medical Center, University of Southern California, 1500 San Pablo Street, Los Angeles, CA 90033, USA

Seromucinous hamartoma is an extremely rare entity that has been described in the sinonasal cavity and nasopharynx. We here present a case of seromucinous hamartoma manifesting as an obstructive endobronchial mass in a 65-year-old male and active smoker, who presented with dyspnea upon prolonged exertion and atelectasis.

Citation: Guang-Qian X, Patel S (2017) Seromucinous Hamartoma Presenting as an Obstructive Endobronchial Mass. Int J Respir Pulm Med 4:066.



 Original Research 


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Published Date
January 21, 2017

Vol. 4, Issue 1

Effects of Chest Physical Therapy in Patients with Non-Tuberculous Mycobacteria

Basavaraj Ashwin, Segal Leopoldo, Samuels Jonathan, Feintuch Jeremy, Feintuch Joshua, Alter Kevin, Moffson Daniella, Scott Adrienne, Addrizzo-Harris Doreen, Liu Mengling and Kamelhar David

Corresponding author: Ashwin Basavaraj, Critical Care and Sleep Medicine, Division of Pulmonary, New York University School of Medicine, 462, 1st Avenue, NBV 7N24, New York, NY 10016, USA

Antibiotic therapy against non-tuberculous mycobacteria (NTM) is prolonged and can be associated with toxicity. We sought to evaluate whether chest physical therapy (PT) was associated with clinical improvement in patients with NTM not receiving anti-mycobacterial pharmacotherapy. A retrospective review of 77 subjects that were followed from June 2006 to September 2014 was performed. Baseline time point was defined as the first positive sputum culture for NTM; symptoms, pulmonary function, and radiology reports were studied. Subjects were followed for up to 24 months and results analyzed at specified time points.

Citation: Ashwin B, Leopoldo S, Jonathan S, Jeremy F, Joshua F, et al. (2017) Effects of Chest Physical Therapy in Patients with Non-Tuberculous Mycobacteria. Int J Respir Pulm Med 4:065.



 Review Article 


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Published Date
December 12, 2016

Vol. 3, Issue 4

Inhaler Technology

Gumani D, Newmarch William, Puopolo Angelica and Casserly Brian

Corresponding author: Gumani D, Department of Internal Medicine, University of Limerick, Ireland

Inhalers are a commonly used device to deliver medication to individuals with airway disease. With correct use, inhalers are very effective at providing quick and effective symptomatic relief within the lung, avoiding high levels of systemic exposure. These pharmacokinetic characteristics widen the therapeutic index, thus allowing for maximal therapeutic benefit with minimal adverse effects. However, this theoretical advantage is somewhat attenuated by incorrect use of the inhaler device.

Citation: Gumani D, William N, Angelica P, Brian C (2016) Inhaler Technology. Int J Respir Pulm Med 3:064.



 Editorial 


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Published Date
November 28, 2016

Vol. 3, Issue 4

New Guidelines, Less Guidance, and the End of an Era: Healthcare -Associated Pneumonia in 2016

Jeena Jacob and Matthew Crotty

Corresponding author: Matthew Crotty, PharmD, Department of Pharmacy, Methodist Dallas Medical Center 1441 N. Beckley Ave, Dallas, TX 75203, USA

The 2005 guidelines recommended classification of patients based on their risk of infection by resistant bacterial pathogens. The now abandoned HCAP entity included any patient hospitalized in an acute care hospital for two or more days within 90 days of the infection; residing in a nursing home or long-term care facility; exposed to recent intravenous antibiotic-therapy, chemotherapy, or wound care within the past 30 days of the current infection; or on hemodialysis.

Citation: Jacob J, Crotty M (2016) New Guidelines, Less Guidance, and the End of an Era: Healthcare -Associated Pneumonia in 2016. Int J Respir Pulm Med 3:063e.



 Original Research 


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Published Date
November 21, 2016

Vol. 3, Issue 4

Relationship between Documented Confirmation of Endotracheal Tube Position and Mortality in the Emergency Department

Michael P Phelan, Jonathan M Glauser, Fredric M Hustey, Motunrayo Mobolaji-Lawal and Stephen W Meldon

Corresponding author: Michael P Phelan, MD, Emergency Services Institute, Cleveland Clinic Health Systems, 9500 Euclid Avenue, Cleveland OH 44195, USA

We analyzed an emergency department (ED) performance improvement (PI) database from an airway registry that was developed to monitor the care of patients undergoing endotracheal intubation in prehospital settings or in the study site ED. PI initiatives included implementation of electronic health record (EHR) documentation templates for ETT placement/confirmation, an online educational module, and performance feedback.

Citation: Phelan MP, Glauser JM, Hustey FM, Mobolaji-Lawal M, Meldon SW (2016) Relationship between Documented Confrmation of Endotracheal Tube Position and Mortality in the Emergency Department. Int J Respir Pulm Med 3:062.



 Research Article 


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Published Date
November 06, 2016

Vol. 3, Issue 4

Smoking Habit in Adult Population from Maracaibo City, Venezuela

Valmore Bermudez, Edgar Miquilena, Juan Salazar, Robys Gonzalez, Luis Carlos Olivar, Maria Jose Calvo, Roberto Anez, Jose R Rivas-Rios and Joselyn Rojas

Corresponding author: Juan Salazar, MD, Endocrine and Metabolic Research Center "Dr. Felix Gomez", School of Medicine, University of Zulia, Maracaibo, Venezuela

A descriptive, cross-sectional research study, framed in the study Prevalence of Metabolic Syndrome in Maracaibo city conformed by 2,212 adults of both genders; based on the medical information the individuals were classified in smokers, non-smokers and former smokers. Quantitative variables were expressed as medians and qualitative variables as absolute and relative frequencies, using χ2 for significance and Z test for difference of proportions.

Citation: Bermudez V, Miquilena E, Salazar J, Gonzalez R, Olivar LC, et al. (2016) Smoking Habit in Adult Population from Maracaibo City, Venezuela. Int J Respir Pulm Med 3:061.



 Case Report 


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Published Date
October 17, 2016

Vol. 3, Issue 4

Possible Complication of Marking Hook Wire Entry into the Systemic Circulation during Video-Assisted Thoracoscopic Surgery

Hiromasa Arai, Michihiko Tajiri, Kohei Ando, Koji Okudela, Tae Iwasawa and Munetaka Masuda

Corresponding author: Hiromasa Arai, Department of General Thoracic Surgery, Yokohama City University Graduate School of Medicine, 6-16-1 Tomiokahigashi, Kanazawa-ku, Yokohama, 236-8651, Japan

A 63-year-old Japanese male suffering from interstitial pneumonia underwent computed tomography (CT) guided tumor localization using a hook wire and a suture system for a small pulmonary nodule suspected of being lung carcinoma. He underwent subsequent video-assisted thoracoscopic surgery. The cut suture connecting to the metal head of the hook wire in the lung parenchyma was visible at the beginning of the procedure. During the surgery, the suture was not able to be visualized.

Citation: Arai H, Tajiri M, Ando K, Okudela K, Iwasawa T, et al. (2016) Possible Complication of Marking Hook Wire Entry into the Systemic Circulation during Video-Assisted Thoracoscopic Surgery. Int J Respir Pulm Med 3:060.



 Original Article 


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Published Date
October 03, 2016

Vol. 3, Issue 4

Clinical and Radiological Predictor of Polymyositis and Dermatomyositis Associated Interstitial Lung Disease

Tomoo Kishaba, Hiroaki Nagano, Yuichiro Nei, Shin Yamashiro and Harumi Ito

Corresponding author: Tomoo Kishaba, Department of Respiratory Medicine, Okinawa Chubu Hospital, 904-2293 Miyazato 281, Uruma, Okinawa, Japan

Background: Polymyositis (PM) and dermatomyositis (DM) often have interstitial lung disease (ILD) and progression of ILD is important cause of death. Objectives: This study is conducted to clarify the important clinical, radiological factors of PM/DM ILD patients. Methods: We reviewed medical records, pulmonary function test (PFT), chest high-resolution computed tomography (HRCT) findings from January 1, 2001 to December 31, 2014 retrospectively at Okinawa Chubu Hospital.

Citation: Kishaba T, Nagano H, Nei Y, Yamashiro S, Ito H (2016) Clinical and Radiological Predictor of Polymyositis and Dermatomyositis Associated Interstitial Lung Disease. Int J Respir Pulm Med 3:059.



 Original Article 


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Published Date
October 01, 2016

Vol. 3, Issue 4

Drainage using Chest Tubes Smaller than 20 French is Suitable for Patients with Thoracic Empyema

Ryo Matsunuma, Kazumasa Kase, Nobuhiro Asai, Satoshi Watanabe, Yuko Waseda, Norihiro Kaneko, Masahiro Aoshima, Masaki Fujimura and Kazuo Kasahara

Corresponding author: Ryo Matsunuma, Department of Respiratory Medicine, Komatsu Municipal Hospital, Mukaimoto-orimachi, Komatsu city, Ishikawa, Japan

Background: Patients with thoracic empyema occasionally require chest tubes for drainage. Several studies have reported that smaller chest tubes are effective and cause fewer complications. The aim of this study was to investigate the outcomes of patients with empyema who underwent drainage using a smaller-size chest tube. Methods: We retrospectively reviewed all patients at 2 institutions with thoracic empyema. We performed both univariate and multivariate analysis to examine the relation between tube size and the incidence of complications.

Citation: Matsunuma R, Kase K, Asai N, Watanabe S, Waseda Y, et al. (2016) Drainage using Chest Tubes Smaller than 20 French is Suitable for Patients with Thoracic Empyema. Int J Respir Pulm Med 3:058.



 Case Report 


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Published Date
September 19, 2016

Vol. 3, Issue 3

Cross-Antigenicity of Paragonimus Westermani Egg Yolk Cells with Antibody against Surfactant Protein-D (SP-D) in Pulmonary Necrotizing Granuloma in a Native Japanese Woman

Yuji Ohtsuki, Shinji Fujioka, Masashi Uomoto, Yasuki Hachisuka, Masataka Korenaga, Atsushi Kurabayashi, Ichiro Murakami and Mutsuo Furihata

Corresponding author: Yuji Ohtsuki, MD, PhD, Department of Diagnostic Pathology, Matsuyama-shimin Hospital, Matsuyama, Ehime 790-0067, Japan

A native Japanese woman in her 60's complained of hemosputum and had an irregular nodular shadow in her chest radiograph. The nodule was surgically removed, and the histopathological findings of the pulmonary lesion showed a necrotizing granuloma with central irregular geographic necrosis associated with parasite eggs. The results of the enzyme-linked immunosorbent assay of her serum confirmed Paragonimus westermani (Pw) infection as the cause, owing to her history of ingesting uncooked wild boar meat. Interestingly, immunohistochemical results demonstrated that the Pw egg yolk cells could react with antibody against surfactant protein D (SP-D).

Citation: Ohtsuki Y, Fujioka S, Uomoto M, Hachisuka Y, Korenaga M, et al. (2016) Cross-Antigenicity of Paragonimus Westermani Egg Yolk Cells with Antibody against Surfactant Protein-D (SP-D) in Pulmonary Necrotizing Granuloma in a Native Japanese Woman. Int J Respir Pulm Med 3:057.



 Case Report 


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Published Date
September 02, 2016

Vol. 3, Issue 3

Sarcoidosis Presenting with Severe Thrombocytopenia

Yusuf Kayar, Nuket Bayram Kayar, Nurcan Unver and Iskender Ekinci

Corresponding author: Yusuf Kayar, MD, Department of Internal Medicine, Bezmialem Vakif University, Vatan street, Fatih, Istanbul, Turkey

Sarcoidosis is a systemic granulomatous disorder of unknown causes. Haematological manifestations in sarcoidosis are uncommon and may include haemolytic anemia, leukopenia, eosinophilia and peripheral lymphopenia, but severe thrombocytopenia is rare. Causes of thrombocytopenia in sarcoidosis were identified a few mechanisms. There are no current guidelines concerning the treatment of thrombocytopenia in sarcoidosis. However, in emergency situations with major thrombocytopenia, it seems reasonable to apply current guidelines recommended forIdiopathic Thrombocytopenic Purpura. We reported a case of sarcoidosis presenting with severe thrombocytopenia, petechial rash and gingival bleeding.

Citation: Kayar Y, Kayar NB, Unver N, Ekinci I (2016) Sarcoidosis Presenting with Severe Thrombocytopenia. Int J Respir Pulm Med 3:056.



 Original Article 


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Published Date
September 01, 2016

Vol. 3, Issue 3

Impact of Bariatric Surgery on Obstructive Sleep Apnoea in Morbidly Obese Patients; Single Centre Experience and a Literature Review

Muhammad Ali Karim, Muhammad Josheel Naveed, Amir Hussein and Abdulmajid Ali

Corresponding author: Mr. Abdulmajid Ali, Consultant Upper GI and Bariatric Surgeon, Department of Surgery, University Hospital Ayr, Ayrshire and Arran, Dalmellington Road, KA6 6DX, UK

Purpose: Bariatric surgery is an established treatment of morbid obesity and effectively controls symptoms of OSAHS. The aim of this study was to evaluate impact of bariatric surgery on OSAHS. Methods: Validated Epworth Sleepiness Score (ESS) and STOP-Bang questionnaires were used to assess the impact of bariatric surgery on OSAHS in morbidly obese patient's undergone bariatric surgery from May 2008 to December 2011. Change in ESS, STOP-Bang score, weight and BMI, co-morbidities and CPAP requirement were recorded. EMBASE, MEDLINE and COCHRANE database were searched for relevant literature.

Citation: Karim MA, Naveed MJ, Hussein A, Ali A (2016) Impact of Bariatric Surgery on Obstructive Sleep Apnoea in Morbidly Obese Patients; Single Centre Experience and a Literature Review. Int J Respir Pulm Med 3:055.



 Review Article 


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Published Date
August 25, 2016

Vol. 3, Issue 3

The Role of Histone Deacetylase Inhibitors in Myocardial Infarction

Ping Zeng and Jian Yang

Corresponding author: Jian Yang, Department of Cardiology, First College of Clinical Medical Sciences, Institute of Cardiovascular Diseases, China Three Gorges University, Yichang 443000, Hubei Province, China

Myocardial infarction is usually recognized as the final stage of coronary artery stenosis or occlusion in response to coronary atherosclerosis and thrombosis involving dysfunction and activation of resident vascular cells as well as the release of t-PA. As a member of family proteins for deacetylation of core histones in eukaryotic cells, Histone deacetylases are implicated in various biological processes.

Citation: Zeng P, Yang J (2016) The Role of Histone Deacetylase Inhibitors in Myocardial Infarction. Int J Respir Pulm Med 3:054.



 Original Article 


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Published Date
August 23, 2016

Vol. 3, Issue 3

Role of Tissue Doppler, Strain and 3D Echocardiographic Parameters in Pulmonary Hypertension

Marta Afonso Nogueira, Luisa Moura Branco, Ana Agapito, Ana Galrinho, Alexandra Borba, Ruben Ramos, Duarte Cacela and Rui Cruz Ferreira

Corresponding author: Marta Afonso Nogueira, MD, Servico de Cardiologia, Hospital de Santa Marta, Rua de Santa Marta, 1169-024, Lisboa, Portugal

Several echocardiographic parameters study right ventricular (RV) function, which has a prognostic impact on pulmonary hypertension (PH). Our goal was to evaluate the correlation between known prognostic markers and standard, as well as advanced echocardiographic parameters, including Tissue Doppler (TDI), strain imaging and three-dimensional (3D) echocardiography.

Citation: Nogueira MA, Branco LM, Agapito A, Galrinho A, Borba A, et al. (2016) Role of Tissue Doppler, Strain and 3D Echocardiographic Parameters in Pulmonary Hypertension. Int J Respir Pulm Med 3:053.



 Case Report 


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Published Date
August 22, 2016

Vol. 3, Issue 3

Diffuse Alveolar Hemorrhage as a Initial Manifestation of Henoch-Schonlein Purpura in Adults

Carmen Carrasco Cubero and Chamizo Carmona

Corresponding author: Carmen Carrasco Cubero, Service of Rheumatology, Hospital Infanta Cristina, Avenida Damian Tellez Lafuente, Badajoz, Spain

Henoch-Schonlein purpura (HSP) is a systemic vasculitis that affects small-sized vessels, characterized by non-thrombocytopenic purpura, along with other clinical manifestations such as arthritis, abdominal pain, gastrointestinal bleeding and renal disease. Although the presence of subclinical alterations of pulmonary function has been noticed, the appearance of diffuse alveolar hemorrhage (DAH) is a rather an unusual symptom. We report a case of HSP with DAH as initial manifestation.

Citation: Cubero CC, Carmona C (2016) Diffuse Alveolar Hemorrhage as a Initial Manifestation of Henoch-Schonlein Purpura in Adults. Int J Respir Pulm Med 3:052.



 Original Article 


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Published Date
August 16, 2016

Vol. 3, Issue 3

Extubation Outcome using Cough Expiratory Flow in Surgical Patients: An Observational Study

Ming-Shian Lu, Tsung-Ming Yang, Cheng-Chih Chang, Chien-Chao Lin, Yao-Kuang Huang and Ying-Huang Tsai

Corresponding author: Dr. Ying-Huang Tsai, Division of Pulmonary and Critical Care Medicine, Chang Gung Memorial Hospital at Chia Yi, ChiaYi County, Taiwan

We conducted a one-year prospective observational study of adult post-surgical patients admitted to the surgical intensive care unit and mechanically ventilated for more than 24 hours. Forced cough peak expiratory flow (FCPEF) was assessed by using a digital peak flow meter placed in-line with the endotracheal before extubation after passing previously a spontaneous breathing trial.

Citation: Ming-Shian L, Tsung-Ming Y, Cheng-Chih C, Chien-Chao L, Yao-Kuang H, et al. (2016) Extubation Outcome using Cough Expiratory Flow in Surgical Patients: An Observational Study. Int J Respir Pulm Med 3:051.



 Case Report 


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Published Date
July 11, 2016

Vol. 3, Issue 3

An Unusual Case of Recurrent Post-Obstructive Pneumonia from Spontaneous Granulation Tissue Formation

Georges Al-Helou, Sripooja Satya, Brian Senisi, Robert Maximos and Jalil Ahari

Corresponding author: Georges Al-Helou, MD, Pulmonary and Critical Care Division, George Washington University Hospital, 2150 Pennsylvania Ave NW, Washington DC, 20037, USA

A 63-year-old man known to have human immune-deficiency viral (HIV) infection was referred for evaluation following three episodes of left upper lobe pneumonia. He was well controlled on his anti-retroviral medications. Physical exam showed left upper lobe wheezing. No evidence of obstruction could be seen on chest X-ray or computed tomography (CT). Bronchoscopy was done and showed an obstructing lesion that was biopsied then ablated. It was found to be due to a spontaneous formation of granulation tissue with no identifiable cause.

Citation: Al-Helou G, Satya S, Senisi B, Maximos R, Ahari J (2016) An Unusual Case of Recurrent Post-Obstructive Pneumonia from Spontaneous Granulation Tissue Formation. Int J Respir Pulm Med 3:050.



 Original Article 


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Published Date
June 30, 2016

Vol. 3, Issue 2

Objective Quantitative CT Evaluation using Different Attenuation Ranges in Patients with Pulmonary Fibrosis: Correlations with Visual Scores

Shin Matsuoka, Tsuneo Yamashiro, Shoichiro Matsushita, Atsuko Fujikawa, Kunihiro Yagihashi and Yasuo Nakajima

Corresponding author: Shin Matsuoka, MD, Department of Radiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-Ku, Kawasaki, Kanagawa, 216-8511, Japan

Objective quantitative evaluation for the extent of fibrosis has been introduced using CT densitometry in patients with interstitial lung diseases, however, there have been no definitive attenuation cut-off values to evaluate the extent of ground-glass opacity and fibrosis separately. This study was conducted to investigate the relationships between quantitative CT measurements using different attenuation ranges and visual CT scores, and to determine whether the different attenuation ranges can estimate the extent of ground-glass opacity and fibrosis separately in patients with pulmonary fibrosis.

Citation: Matsuoka S, Yamashiro T, Matsushita S, Fujikawa A, Yagihashi K, et al. (2016) Objective Quantitative CT Evaluation using Different Attenuation Ranges in Patients with Pulmonary Fibrosis: Correlations with Visual Scores. Int J Respir Pulm Med 3:049.



 Original Research Article 


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Published Date
May 23, 2016

Vol. 3, Issue 2

Prevalence of Chronic Obstructive Pulmonary Disease in Southwestern Taiwan: A Population-Based Study

Su-Lun Hwang, Yu-Ching Lin, Su-Er Guo, Miao-Ching Chi, Chiang-Ting Chou and Chieh-Mo Lin

Corresponding author: Su-Lun Hwang, Assistant Professor, Department of Nursing, Chang Gung University of Science and Technology, Chiayi Campus, Chiayi County 61363, Taiwan

Objective: Chronic obstructive pulmonary disease (COPD) poses a substantial burden of illness in the Asia-Pacific region, as it does worldwide. However large-scale and community-based epidemiology studies of COPD in Taiwan are limited. This paper conducted a population-based study to investigate the prevalence of COPD in southwestern Taiwan. Methods: Data were conducted using a subset of medical claims data from the National Health Insurance Research database (NHIRD) from 2008 to 2010. The prevalence of COPD was calculated for the population aged 40 years and older in southwestern Taiwan. The relative risks (RRs) of prevalence for COPD was estimated using a multiple linear regression model.

Citation: Su-Lun H, Yu-Ching L, Su-Er G, Miao-Ching C, Chiang-Ting C, et al. (2016) Prevalence of Chronic Obstructive Pulmonary Disease in Southwestern Taiwan: A Population-Based Study. Int J Respir Pulm Med 3:048.



 Original Research Article 


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Published Date
May 09, 2016

Vol. 3, Issue 2

Outcome Predictors of Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Role of Inflammatory Biomarkers

Hanaa Shafiek, Nashwa Abd-elwahab, Manal Baddour, Akram Degady, Mohamed El-hoffy and Yehia Khalil

Corresponding author: Hanaa Shafiek, MD, PhD, Chest Diseases Department, Faculty of Medicine, Alexandria University, El-Khartoom Square, Alexandria 21526, Egypt

Objective: To assess the value of interleukin-6 (IL-6), interleukin-8 (IL-8) and C-reactive protein (CRP) in predicting the outcome of acute respiratory failure (ARF) on top of COPD. Patients and methods: Serum samples were collected from 33 COPD patients presented with ARF for IL-6, IL-8, and CRP analysis on admission, after 72 hours and after 14 days. Sputum samples were taken for microbiological evaluation.

Citation: Shafiek H, Abd-elwahab N, Baddour M, Degady A, El-hoffy M, et al. (2016) Outcome Predictors of Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Role of Inflammatory Biomarkers. Int J Respir Pulm Med 3:047.



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