| Research Article |
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August 19, 2016
|Vol. 3, Issue 1|
Protease Biosensors Based on Peptide-Nanocellulose Conjugates: From Molecular Design to Dressing Interface
J Vincent Edwards, Krystal R Fontenot, Nicolette T Prevost, David Haldane, Nicole Pircher, Falk Liebner, Alfred French and Brian D Condon
Corresponding author: J Vincent Edwards, Cotton Chemistry and Utilization Research, United States Department of Agriculture, 1100 Robert E. Lee Blvd, New Orleans, LA 70124, USA
The development of point of care diagnostic protease sensors applied to wound healing has received increased interest in chronic wound treatment as an interface for chronic wound dressings. Biosensor technology and the use of nanomaterials have grown exponentially in recent years. A biosensor is fundamentally a biomolecule (functioning as a transducer) attached to a transducer surface, which is activated by a biochemical property that prompts a detection signal specific to a target biomarker. For instance, nanomaterials are often derivatized with a biomolecule that provides selectivity and sensitivity for diagnostic biomarkers.
Citation: Edwards JV, Fontenot KR, Prevost NT, Haldane D, Pircher N, et al. (2016) Protease Biosensors Based on Peptide-Nanocellulose Conjugates: From Molecular Design to Dressing Interface. Int J Med Nano Res 3:018.