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 Research Article 


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Published Date
December 01, 2016

Vol. 3, Issue 6

Cancer Antigen 125 Levels can be Used as a Tumor Marker for Monitoring Patients with Endometrial Serous Carcinoma?

MW Hegazy, Wael H Elsawy, A Tolba and M Shoukri

Corresponding author: Mohamed W Hegazy, Department of Radiation Oncology, King Faisal Specialist Hospital & Research Center, Kingdom of Saudi Arabia, PO Box 3354, Riyadh 11211 MBC 64, Saudi Arabia

Endometrial adenocarcinoma is the most common type of uterine cancer. Endometrial cancer is classified into two subtypes (I and II), which reflect general characteristics of its clinicopathological spectrum. Uterine serous adenocarcinoma (USAC) is under Type II neoplasms which are associated with more aggressive behavior than type I tumors. While they comprise 10-20% of endometrial carcinomas, they account for 40% of deaths from the disease.

Citation: Hegazy MW, Elsawy WH, Tolba A, Shoukri M (2016) Cancer Antigen 125 Levels can be Used as a Tumor Marker for Monitoring Patients with Endometrial Serous Carcinoma?. Int J Cancer Clin Res 3:075.



 Clinical Image 


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Published Date
November 26, 2016

Vol. 3, Issue 6

Massive Arterial Bleeding after Lenvatinib Therapy for Thyroid Cancer

Koichi Suyama, DaizoMurakami, Saori Fujiwara, Takashi Takeshita, Aiko Sueta, ToukoInao, Mutsuko Yamamoto-Ibusuki, Yutaka Yamamoto, Shin-yaShiraishi and Hirotaka Iwase

Corresponding author: Koichi Suyama, Kumamoto University Hospital Cancer Center, Graduate School of Life Sciences, Kumamoto University, 1-1-1, Honjyo, Chuo-ku, Kumamoto-city, 860-8556, Kumamoto, Japan

A 69-year-old woman presented with hoarseness and other symptoms of laryngeal stenosis. A palpably large tumorin her neck was shown by computed tomography (CT) to expand invasively from her upper left thyroid lobe, and to involve her left common carotid artery and internal jugular vein (Figure 1 A-1). The diagnosis of papillary thyroid cancer was based on cytological evidence from fine needle aspiration biopsy.

Citation: Suyama K, Murakami D, Fujiwara S, Takeshita T, Sueta A, et al. (2016) Massive Arterial Bleeding after Lenvatinib Therapy for Thyroid Cancer. Int J Cancer Clin Res 3:074.



 Short Review 


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Published Date
November 26, 2016

Vol. 3, Issue 6

Pigmented Paget Disease of the Nipple: A Rare Breast Cancer Presentation

Santiago Sherwell-Cabello, Antonio Maffuz-Aziz, Silvia Natalia Lopez-Hernandez, Melissa Lizeth Flores-Cortes, Veronica Bautista-Pina and Sergio Rodriguez-Cuevas

Corresponding author: Santiago Sherwell-Cabello, Instituto de Enfermedades de la Mama, FUCAM AC, Bordo 100, StaUrsula Coapa, Coyoacan 04980, Mexico City, Mexico

Institutional board approval was obtained before commencement of this study. A retrospective study was conducted in all women diagnosed with breast cancer at our institution from January 2005 to December 2013. Standard immunohistochemical breast cancer panel was performed to all patients (ER, PR, Her-2 and Ki-67) and CK-7, P63 and S-100 when the pigmented variety was presented. Patients with pigmented Paget disease were selected and demographic characteristics were established.

Citation: Sherwell-Cabello S, Maffuz-Aziz A, Lopez-Hernandez SN, Flores-Cortes ML, Bautista-Pina V, et al. (2016) Pigmented Paget Disease of the Nipple: A Rare Breast Cancer Presentation. Int J Cancer Clin Res 3:073.



 Review Article 


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Published Date
November 19, 2016

Vol. 3, Issue 6

Colorectal Cancer Aggressiveness is Related to Fibronectin Over Expression, Driving the Activation of SDF-1:CXCR4 Axis

Sofia Gouveia-Fernandes, Tania Carvalho, Germana Domingues, Renata Bordeira-Carrico, Sergio Dias and Jacinta Serpa

Corresponding author: Jacinta Serpa, Centro de Estudos de Doencas Cronicas (CEDOC), NOVA Medical School, Universidade NOVA de Lisboa Campo Martires da Patria 130, 1169-056 Lisbon, Portugal

Cancer hallmarks result from dynamical interactions between tumor cells and tumor microenvironment, including normal cells, growth factors and extracellular matrix (ECM) components. Fibronectin (FN) is a high molecular weight, multidomain glycoprotein, present as a soluble form in body fluids, such as plasma (plasma FN), and as an insoluble form in ECM (cellular FN).

Citation: Gouveia-Fernandes S, Carvalho T, Domingues G, Bordeira-Carrrico R, Sergio Dias, et al. (2016) Colorectal Cancer Aggressiveness is Related to Fibronectin Over Expression, Driving the Activation of SDF-1:CXCR4 Axis. Int J Cancer Clin Res 3:072.



 Case Report 


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Published Date
November 16, 2016

Vol. 3, Issue 6

Prolonged Use of Aprepitant in Metastatic Breast Cancer and a Reduction in CA153 Tumour Marker Levels

Mark Lee, Matthew McCloskey and Stephanie Staples

Corresponding author: Mark Lee, St Benedict's Hospice, St Benedict's Way, Ryhope, Sunderland SR2 0NY, UK

Nausea and vomiting are common problems in patients with advanced cancer. This case report describes a patient whose refractory nausea and vomiting improved significantly with the use of Aprepitant, a highly selective neurokinin 1 receptor antagonist. This improvement led to prolonged daily administration, during which time no chemotherapy or hormone therapy was administered. CA153 tumour markers were noted to have fallen during administration.

Citation: Lee M, McCloskey M, Staples S (2016) Prolonged Use of Aprepitant in Metastatic Breast Cancer and a Reduction in CA153 Tumour Marker Levels. Int J Cancer Clin Res 3:071.



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International Journal of Cancer and Clinical Research (ISSN: 2378-3419)
International Journal of Clinical Cardiology (ISSN: 2469-5696)
Journal of Clinical Gastroenterology and Treatment (ISSN: 2469-584X)
Clinical Medical Reviews and Case Reports (ISSN: 2378-3656)
Journal of Dermatology Research and Therapy (ISSN: 2469-5750)
International Journal of Diabetes and Clinical Research (ISSN: 2377-3634)
Journal of Family Medicine and Disease Prevention (ISSN: 2469-5793)
Journal of Genetics and Genome Research (ISSN: 2378-3648)
Journal of Geriatric Medicine and Gerontology (ISSN: 2469-5858)
International Journal of Immunology and Immunotherapy (ISSN: 2378-3672)
International Journal of Medical Nano Research (ISSN: 2378-3664)
International Journal of Neurology and Neurotherapy (ISSN: 2378-3001)
International Archives of Nursing and Health Care (ISSN: 2469-5823)
International Journal of Ophthalmology and Clinical Research (ISSN: 2378-346X)
International Journal of Oral and Dental Health (ISSN: 2469-5734)
International Journal of Pathology and Clinical Research (ISSN: 2469-5807)
International Journal of Pediatric Research (ISSN: 2469-5769)
International Journal of Respiratory and Pulmonary Medicine (ISSN: 2378-3516)
Journal of Rheumatic Diseases and Treatment (ISSN: 2469-5726)
International Journal of Sports and Exercise Medicine (ISSN: 2469-5718)
International Journal of Stem Cell Research & Therapy (ISSN: 2469-570X)
International Journal of Surgery Research and Practice (ISSN: 2378-3397)
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International Journal of Virology and AIDS (ISSN: 2469-567X)
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