Open Access DOI:10.23937/2469-5696/1410002

Pharmacological Treatment may Impair Mineral Status in Blood

Joanna Suliburska

Article Type: Editorial | First Published: July 31, 2014

Some medicines may interact with mineral, with the result that changes occur in the concentration of minerals and other blood parameters that are associated with mineral status. Interpretation of the results of morphological and biochemical blood analyses therefore needs to take into account the drugs used by patients....

 Open Access DOI:10.23937/2469-5696/1410001

The Progress of Oncolytic Reovirus in Hematologic Malignancies: Can we Combat Blood Cancer with the Cold?

Jun Gong

Article Type: Editorial | First Published: July 30, 2014

Oncolytic reovirus continues to pick up momentum as a novel agent in the treatment of cancer. Since the initial discovery of the virus' tendency to preferentially replicate in transformed cell lines from studies in the late 1970s, reovirus has rapidly progressed from preclinical to clinical trials evaluating its efficacy across a spectrum of malignancies, including hematologic....

 Open Access DOI:10.23937/2469-567X/1510001

Therapeutic Targeting of Structural RNA Motifs in Viral RNA Genomes

Joanna Sztuba-Solinska

Article Type: Editorial | First Published: July 19, 2014

Viral RNA genomes have evolved functional motifs, which act at different stages of their life cycle. These unique structural domains, their interactions and association with host proteins and ligands, together orchestrate the multifunctionality of viral RNA genomes. Often, long-range RNA-RNA interactions bring regulatory elements into proximity, changing our view of a functional viral RNA genome from a linear molecule to one whose three-dimensional structure is an important contributor during th...

 Open Access DOI:10.23937/2377-3634/1410001

The Role of OSA on Metabolic Disorders

Patrizio Tatti

Article Type: Editorial | First Published: October 01, 2014

Obstructive Sleep Apnea (OSA) is a frequent disorder in the general population, and even more common in the diabetic population, with incidences reported ranging from 17 to 48%, although these figures are probably an underestimation. As this disorder is so widespread, it is often accepted and dismissed. Patients themselves, often omit mentioning that they suffer from sleep apnea to the doctor. In extreme cases various surgical interventions have used, however with not great success, some reports...

 Open Access DOI:10.23937/2378-2951/1410001

Treatment of Dyslipidemia in Diabetics

Wilbert S. Aronow

Article Type: Editorial | First Published: September 01, 2014

Dyslipidemia in diabetics should be treated with lifestyle measures. Statins are the only lipid-lowering drugs that have been demonstrated to lower the incidence of cardiovascular events and mortality in patients with diabetes mellitus. This review article will discuss the treatment of dyslipidemia in diabetics and the current guidelines supporting the use of statins in the treatment of diabetics....

 Open Access DOI:10.23937/2377-4630/1001

Anesthesia and Critical Care: Profession or Art?

Giustiniano Enrico

Article Type: Editorial | First Published: July 10, 2014

If I ask to a man on the street about Medicine and its progress, only few events came to his mind. Antimicrobial therapy, vaccinations, surgical therapy of cancer and continuous surgical innovations, to cite only some instances, did ameliorate human health. But most of the people forget that many surgical innovations and the care of a lot of infectious disease were due to the birth and upgrading of an often neglected branch of Medicine: Anesthesia and Intensive Care. Furthermore, if I ask to a m...