Open Access DOI:10.23937/2378-3664/1410001
Boron Neutron Capture Therapy of Cancer as a Part of Modern Nanomedicine
Alexander V. Safronov
Article Type: Editorial | First Published: August 16, 2014
Boron neutron capture therapy (BNCT) is a method of cancer therapy with a simple idea behind it. Positioning a certain amount of 10B-enriched boron-containing compounds into tumor cells with subsequent irradiation of the tumor tissue by thermal or epithermal neutrons causes tumor damage and death. The mechanism of the tumor cell damage during BNCT is based on the capture-fission reaction between the boron-10 nucleus and a neutron resulting in an α-particle release inside the cell. A success...
Open Access DOI:10.23937/2378-3419/1/1/1001
International Journal of Cancer and Clinical Research- Commited to Ensure Quality Publication in Cancer Research
Sulma I. Mohammed
Article Type: Editorial | First Published: August 20, 2014
With great pleasure we welcome you to the inaugural issue of the International Journal of Cancer and Clinical Research. We envision this journal to provide a platform for all cancer researchers around the world to publish their high quality findings in cancer and clinical research as well as a venue to nurture researchers and young investigators in developing countries. The journal aims to accelerate the pace of research, discovery and innovation in clinical research around the globe....
Open Access DOI:10.23937/2377-4630/1004
Intrathecal Dexmedetomidine or Meperidine for Post-spinal Shivering
Mohamed Hamdy Ellakany
Article Type: Research Article | First Published: September 11, 2014
Background: Shivering occurs frequently during the perioperative period. A prospective, randomized, double-blind study was done to compare between intrathecal dexmedetomidine (5mcg) and intrathecal meperidine (0.2mg/kg) for decreasing the incidence and intensity of shivering after spinal anesthesia for lower abdominal operations.
Methods: Seventy five patients scheduled for lower abdominal operations under spinal anesthesia were randomly allocated to three groups. Spinal anesthesia consisted o...
Open Access DOI:10.23937/2378-3656/1410001
Validity of Creatine Kinase as an Indicator of Muscle Injury in Spine Surgery and its Relation with Postoperative Pain
Domingo Lombao Iglesias, Joan Bago Granell, Teresa Vilor Ribero
Article Type: Research Article | First Published: September 10, 2014
Injury to the paraspinal muscle during posterior spinal surgery has been related to the intensity of postoperative pain. The aim of the study was to confirm the validity of serum postoperative creatine kinase (CK) values as an indicator of muscle lesion as well as to assess the relationship of CK with variables indicating surgical invasiveness and investigate the association between CK values and excessive postoperative pain.
Material and Method: The study included 96 patients (mean age 62.8 y...
Open Access DOI:10.23937/2377-4630/1005
Anaesthetic Management in a Patient with Glomus Jugulare Tumour for Ankle Surgery
Monu Yadav, R Gopinath, B Rajesh Kumar, Shibani Padhy, A Anand Ram and Suresh Kumar Chintha
Article Type: Case Report | First Published: September 11, 2014
Anaesthesia has special considerations in any case of intracranial space occupying lesions. Not much of literature is available about anaesthetic considerations in a patient with Glomus jugulare tumour requiring surgery for non neurosurgical procedure. Glomus jugulare tumours arise from the glomus body within the adventitia of the jugular bulb. Glomus bodies are histologically similar to carotid bodies. They are composed of epitheloid cells embedded in capillary net work. Occasionally these tumo...
Open Access DOI:10.23937/2378-3648/1410001
Extremely High Carrier Frequency of the GJB2 Splice Site IVS1+1G>A Mutation in Eastern Siberia is Comparable to the Carrier Frequency of the Sickle Cell Anemia in Africa
Nikolay A. Barashkov, Aisen V. Solovyev, Fedor M. Teryutin, Vera G. Pshennikova1, Leonid A. Klarov, Georgii P. Romanov, Sergey S. Nakhodkin, Kyunney E. Savvinova, Nyurgun N. Gotovtsev, Natalya A. Solovyeva, Andrei A. Kozhevnikov, Lena M. Vasilyeva, Elvira E. Fedotova, Maria V. Pak, Sargylana N. Lekhanova, Elena V. Zakharova, Adyum M. Rafailov, Nikolay V. Luginov, Anatoliy N. Alexeev, Olga L. Posukh, Lilya U. Dzhemileva, Elza K. Khusnutdinova and Sardana A. Fedorova
Article Type: Research article | First Published: September 01, 2014
This study presents data on the carrier frequencies of IVS1+1 G>A mutation in GJB2 gene, causing by autosomal recessive form of deafness among various ethno-geographical groups of Yakut population and in a random sample of the Yakuts. 350 DNA samples of hearing individuals from various ethno-geographical groups of Yakut population: Central (n=60), Vilyui (n=60), Northern (n=60) and random samples of Yakuts (n=170) were obtained from the DNA Bank of the Department of Molecular Genetics of Yakut R...
Open Access DOI:10.23937/2377-4630/1003
MOCA - 'Improving Home Improvement'
Semyon Fishkin
Article Type: Editorial | First Published: August 13, 2014
ABA requires re-certification for all Diplomates of the Board who passed oral exam after 1999. This process called MOCA and designed as a 10 years cycle of activities, which results in re-certification. Anesthesiology is not unique in this process - other 23 specialty Boards require maintenance of the certification program. The goal is to assure continuous improvement, so physicians keep up with growing body of medical knowledge and skills....
Open Access DOI:10.23937/2377-4630/1002
Postoperative Respiratory Complications
Rudin Domi, Myzafer Kaci, Herion Dredha, Artan Bodeci, Hektor Sula, Ilir Ohri, Sokol Paparisto, Gjergj Andrea and Enton Bollano
Article Type: Review | First Published: August 04, 2014
The incidence of postoperative pulmonary complications (PRC) it is recently considered to be up to 5%. In the high-risk group, the incidence may reach or even exceed 20%. The mortality associated with PRC can be ranged 10-25%. Fleischman et al found that the incidence of PRC was higher than perioperative cardiac events, considered to be a common postoperative problem. Other authors reported that PRC is associated with a high morbidity profile....