Open Access DOI:10.23937/2469-5734/1510001

Editor's Note: Inaugural Issue of the International Journal of Oral and Dental Health

James L. Borke

Article Type: Editorial | First Published: February 23, 2015

It is my distinct honor and pleasure to have my remarks included in the inaugural issue of The International Journal of Oral of Dental Health. With the accelerated rate of change brought on by global connectivity and the rapid advance of new technologies, the birth of this 21st century journal addressing current issues in oral and dental health is a welcome addition to the field for clinicians and researchers alike....

 Open Access DOI:10.23937/2469-5696/1410008

Thrombophilia: Demographics and Clinical Presentation in United Arab Emirates

Fatma H Sajwani and Moza A Khuzam

Article Type: Research Article | First Published: February 20, 2015

Thrombophilia is a group of disorders that increases the patient's risk of thrombosis. Inherited causes of thrombophilia are challenging to diagnose and once diagnosed may subject the patient to prolonged treatment. The extent of the condition is not well established in UAE and data on prevalence and demographics are lacking. This study aimed at setting a baseline data on the prevalence, demographics and clinical presentation of thrombophilia in UAE....

 Open Access DOI:10.23937/2378-3656/1410015

Spindle Cell Carcinoma of the Oral Cavity: A Case Report

Ezulia T, Saim L, Primuharsa Putra Sha and MS Kenali

Article Type: Case Report | First Published: January 30, 2015

Spindle Cell Carcinoma (SpCC) also known as sarcomatoid carcinoma is a rare biphasic malignant neoplasm that occurs mainly in the upper aerodigestive tract. It has spindled or pleomorphic tumor cells which simulate a true sarcoma but of epithelial origin. WHO classification has placed this tumour under a highly malignant variant of squamous cell carcinoma and labelled it spindle cell carcinoma. It is known for propensity for recurrence and metastases....

 Open Access DOI:10.23937/2469-5696/1410007

HemoCue versus Complete Blood Count for Hemoglobin Measurement in Adults with Vaso-occlusive Crisis due to Sickle Cell Disease

Michael Bursey, Kane Curtis, Robert Gibson, Hongyan Xu and Matthew Lyon

Article Type: Research Article | First Published: February 17, 2015

Hemoglobin (Hgb) measurement is an important risk-stratification tool for patients presenting to the Emergency Department with vaso-occlusive crisis (VOC) from sickle cell disease (SCD). Point-of- care (POC) Hgb testing such as the HemoCue device decreases time to identification of significant anemia. However, there are no studies evaluating the accuracy of HemoCue testing in patients with SCD and VOC. The purpose of this study was to evaluate the correlation of Hgb measurements from HemoCue com...

 Open Access DOI:10.23937/2469-5726/1510004

Non-Operative Treatment of Knee Osteoarthritis: Fear the Future?

Eduardo Branco de Sousa

Article Type: Editorial | First Published: February 23, 2015

Non-operative treatment of knee osteoarthritis has gained special interest between patients and orthopedic surgeons, not only to alleviate pain and improve function, but also to postpone joint replacements. Projections showed an increase of 673% in the number of arthroplasties to be performed in the United States through 2030....

 Open Access DOI:10.23937/2469-5726/1510003

Differential Diagnosis in Upper Back Pain

Nihal Ozaras

Article Type: Editorial | First Published: February 21, 2015

Upper back pain (UBP) is the pain experienced at the thoracic spine region. Spinal pain prevalence is 66 per 100 people and15% them is UBP. Although it is so frequent, it is less studied than neck or low back pain.It can be seen at any period of life, from childhood to elderly.This article briefly describes differential diagnosis in UBP....

 Open Access DOI:10.23937/2572-4010.1510002

The Pivotal Role of Microbiota in Obesity

L. Bonfrate and P. Portincasa

Article Type: Editorial | First Published: February 25, 2015

In general, obesity is a complex disease that results from the interplay between several determinants. From time to time, a role for host genetics, environment, biological factors, pregnancy and lactation history in mothers, social and cultural influence, and imbalance between energy intake and expenditure has been advocated. Dietary factors modulate the composition of the gut microbiota....

 Open Access DOI:10.23937/2572-4142.1510001

Bring New Advances of Basic Medical Research Closer to Patient Care

Xiaoming Yang

Article Type: Editorial | First Published: February 25, 2015

With great pleasure, I welcome you to the inaugural issue of the International Archives of Translational Medicine. The rapid progress in basic medical research is constantly reframing the paradigm how we prevent, diagnose and treat human diseases....

 Open Access DOI:10.23937/2378-3001/2/1/1021

Long-Term Deep Brain Stimulation for Parkinson's Disease is Associated with Progressive Reduction in Medication Utilization and Cost

Chandler E. Gill, Elyne N. Kahn, Aaron Bowman, Thomas L. Davis, Lily Wang, Yanna Song, Justin R. Smith and David Charles

Article Type: Research Article | First Published: February 23, 2015

Patients with Parkinson's Disease (PD) treated with Deep Brain Stimulation (DBS) typically reduce anti-PD medication use by 25-50% within 6 months of device placement, but whether the reduction is maintained long-term is less clear. We performed a medical record review of 18 patients with PD treated with DBS and 18 matched control patients treated with medications alone and compared their patterns of medication use....

 Open Access DOI:10.23937/2377-3634/1410022

Self-Care among Diabetic Amputee

David Berbrayer

Article Type: Research Article | First Published: February 23, 2015

Background: Diabetic amputees are at increased risk for receiving a second amputation, which may be prevented by proper selfcare. Although existing literature suggests self-care is inadequate among diabetic patients, self-care behaviour after an amputation is unknown. This study aims to identify strategies used by diabetic patients who received a lower-extremity amputation to prevent further amputation. Method: A cross-sectional survey was conducted on patients over 18 years of age who were regi...