Open Access DOI:10.23937/2469-567X/1510025
The Monitoring of Lymphocyte Populations may be Optional in Patients with Suppressed Viremia: A Two Years Observational Study
Carlos Tornero, Marina Llopis, Julian Diaz and Mariangeles Martinez
Article Type: Commentary | First Published: July 25, 2016
The determination of lymphocyte populations (LPs) traditionally has been included in the routine follow-up of HIV-infected patients as an indicator of the degree of immune suppression and of the need to start treatment, select the type of therapy, or prescribe preventive measures against opportunistic infections. However, the variability of the technique produces variations in patients with undetectable viremias that have no clinical consequences but which nevertheless generate uncertainty among...
Open Access DOI:10.23937/2474-3658/1510015
Dengue Fever: Historical Perspective and the Global Response
Tyler Warkentien and Rebecca Pavlicek
Article Type: Review Article | First Published: July 02, 2016
Dengue fever remains an important mosquito-borne viral illness resulting in substantial human and economic costs. Despite rising incidence rates in recent decades, there is cause for hope, particularly in light of recent advancements in dengue vaccine and vector control research. This article reviews past dengue control efforts and discusses current and future strategies for dengue control....
Open Access DOI:10.23937/2378-2951/1410086
Coronary-Cameral Fistula Presenting as Worsening Refractory Heart Failure
Dhruti Mankodi, Ashish Sharma, Fulvia Banu, Sameer Shaharyar, Pedro Martinez-Clark and Ali Bazzi
Article Type: Case Report | First Published: August 12, 2016
Coronary-cameral fistula (CCF) is a rare condition most commonly caused by an embryologic developmental anomaly. Fifty-five percent of CCFs originate from the right coronary artery, 35% from the left coronary artery, and 5% from both. More than 90% of them drain into the venous system and low pressure sites such as the right ventricle (41%), right atrium (26%), pulmonary artery (17%) and only 3% drain into the left ventricle or atrium....
Open Access DOI:10.23937/2469-5696/1410023
Polycythemia Vera with High Erythropoietin Level: Case Report
Rami Nassabein, Mariam al khatib, Marie Helen Abbas, Marie youssef, Daniel Amer and Jaafar Wazni
Article Type: Case Report | First Published: August 30, 2016
Polycythemia Vera (PV) is a myeloproliferative disorder of bone marrow stem cells characterized by erythrocytosis. Elevated erythropoietin level strongly indicates secondary erythrocytosis and excludes PV diagnosis. However, patients with PV who co-present with Budd-Chiari syndrome (BCS) have been documented with elevated serum erythropoietin levels provided that JAK2 mutation is positive....
Open Access DOI:10.23937/2469-5769/1510024
Developing a Culturally Sensitive Training Program for Recognition of Hypoxic Ischemic Encephalopathy in Rural India
Atul Malhotra, Michael C Fahey, Suzanne L Miller, Graham Jenkin, JV Singh, Pawankumar Patil, Vishwajeet Kumar and Euan M Wallace
Article Type: Research Article | First Published: August 24, 2016
Background: Birth asphyxia is a major cause of neonatal deaths in the developing world. The management of an asphyxiated infant includes effective resuscitation at birth and treatment of subsequent hypoxic ischemic encephalopathy (HIE). HIE is frequently under recognized in this setting and this contributes to early infant mortality and morbidity.
Methods: We present the evolution of a HIE recognition training program for rural India. The development of this program involved close community int...
Open Access DOI:10.23937/2469-5769/1510023
A Valuable Tool to Determine Supraventricular Tachycardia in Children: Trans-Esophageal Electrophysiological Study
Seyma Kayal, Ilker Ertugrul, Vehbi Dogan, Senem Ozgur, Utku Arman Orun and Selmin Karademir
Article Type: Original Article | First Published: August 22, 2016
A total of 132 patients who underwent TEEPS at our institution were included. Demographic features and symptoms of patients were evaluated and the patients were divided into three groups to compare the inducibility of tachycardia: Symptom group was consisting of 91 patients who had symptoms of arrhythmias, Wolf Parkinson White group was consisting of 18 patients who had Wolf Parkinson White pattern on surface electrocardiogram, and Tachycardia group was consisting of 23 patients who had previous...
Open Access DOI:10.23937/2469-5769/1510022
Endogenic Intoxication and Kidney
Yurieva Eleonora Alexandrovna, Vozdvizhenskaya Ekaterina Sergeevna, Kushnareva Maria Vasilievna and Novikova Natalia Nicolaevna
Article Type: Review Article | First Published: August 19, 2016
The following information about the endogenous intoxication in children (from 2 up to 17 y.o.) with nephrological diseases was presented. Endogenous intoxication as multisystemic pathological condition occurs as the result of action on the organism of toxic substances of endogenous or exogenous origin. It is characterized by the following: a) violation of the barrier function of the organism against toxins, b) violation of transport mechanisms of toxic substances to the organs of their transform...
Open Access DOI:10.23937/2469-5858/1510014
Type 2 Diabetes in the Elderly: Challenges in a Unique Patient Population
David Bradley and Willa Hsueh
Article Type: Review Article | First Published: September 08, 2016
In the older patient population, rates of Type 2 Diabetes (T2D) and obesity are reaching epidemic proportions. In fact, older patients will soon constitute the majority of patients with T2D in most developed countries. The higher prevalence of T2D in older individuals is seen in both men and women and across racial and ethnic groups. However, certain ethnic groups are disproportionately affected and successful strategies must account for these fundamental differences....
Open Access DOI:10.23937/2572-3243.1510019
A Longitudinal Study of the Prediction of Pathologic Spinal Fractures in Multiple Myeloma with Trabecular Microarchitecture and CT-Based Finite Element Analyses
Miyuki Takasu, Chihiro Tani, Yoko Kaichi, Baba Yasutaka, Chikako Fujioka, Masao Kiguchi, Kumi Oshima, Yoshiaki Kuroda, Akira Sakai, Tatsuo Ichinohe and Kazuo Awai
Article Type: Original Research | First Published: August 16, 2016
A total of 22 vertebral bodies from 14 patients with multiple myeloma were examined by 64-detector row CT prior to follow-up CT that showed new pathologic spinal fractures. Tissue bone mineral density (tBMD), trabecular parameters, and mechanical properties were calculated for three vertebrae, comprising a vertebra that would become fractured and the two adjacent vertebrae. Areas of lytic lesions were also obtained in the axial images containing the largest lytic lesions....