Open Access DOI:10.23937/2378-3001/1410067

Nuclear Localization of Apolipoprotein E4: A New Trick for an Old Protein

Troy T Rohn and Zachary D Moore

Article Type: Mini Review | First Published: July 31, 2017

One of the most important genetic risk factors for late-onset Alzheimer’s Disease (AD) is harboring the APOE4 allele. Much is known regarding the functions of the ApoE4 protein including cholesterol transport in the CNS and a critical role in clearing beta-amyloid deposits in the AD brain....

 Open Access DOI:10.23937/2469-5807/1510057

Endometrioid Adenofibroma: A Case of This Uncommon Benign Tumor of the Ovary Not Associated to Borderline or Endometrioid Carcinoma

Santiago Ortiz and Francisco Tortosa

Article Type: Clinical Images | First Published: June 16, 2017

Endometrioid adenofibroma is a benign epithelial and stromal tumor with an endometrioid epithelial component. Less than 20% of the surface epithelial tumors of the ovary have endometrioid differentiation. The majority of endometrioid ovarian neoplasms are carcinomas and the benign form is rarely find....

 Open Access DOI:10.23937/2469-5734/1510044

Effect of Antibiotic Prophylaxis on Serum CRP Level Immediately Following Periodontal Treatment: An Experimental Clinical Study

Basak Boduroglu, Nilsun Bagis, Cem A Gurgan and Hamit S Bostanci

Article Type: Research Article | First Published: June 08, 2017

The immediate rise in serum C-reactive Protein (CRP) levels associated with the delivery of the subgingival instrumentation and the associated bacteremia and tissue damage was shown shortly after periodontal treatment was delivered....

 Open Access DOI:10.23937/2469-5734/1510043

An Alternative Strategy to Manage a Large Perforation of the Schneiderian Membrane by Staged Re-entry into the Maxillary Sinus: Observed Clinical and Histological Changes of the Regenerated Schneiderian Membrane

Cameron YS Lee

Article Type: Review Article | First Published: June 07, 2017

Maxillary sinus membrane perforation or tear is the most common complication of the sinus grafting procedure. Repair of the sinus membrane is usually accomplished at the time of the sinus graft procedure and often results in uneventful postoperative complications....

 Open Access DOI:10.23937/2469-5793/1510059

Cost of Growing up in Dysfunctional Family

Basem Abbas Al Ubaidi

Article Type: Review Article | First Published: July 31, 2017

The definition of a family dynamic is the scheme of family members' relations and interactions including many prerequisite elements (family arrangements, hierarchies, rules, and patterns of family interactions). Each family is unique in its characteristics....

 Open Access DOI:10.23937/2572-4010.1510018

Prevalence of Prediabetes in Overweight and Obese Children from the Pediatric Consultation of a Second Level Hospital

Jaime Valle Leal, Cecilia C Morales Alvarado and Lucia Alvarez-Bastidas

Article Type: Research Article | First Published: August 03, 2017

Childhood obesity represents a global public health problem, with Mexico occupying the first place in the prevalence of this pathological condition. In our country, this combined prevalence: Obesity and overweight, is reported by up to 39.4% in adolescents, being the most affected age group....

 Open Access DOI:10.23937/2572-4010.1510017

Riopelle Fat Type Level: A Simpler Way for Men to Understand Body Shape and Health Risks

Donna Riopelle and Paulina Van

Article Type: Review Article | First Published: August 03, 2017

Obesity is recognized as a disease entity due to the damage that dysfunctional abdominal visceral fat can cause. Body shape and fat distribution are more predictive of future disease than Weight and Body Mass Index (BMI)....

 Open Access DOI:10.23937/2572-4061.1510007

Accuracy of Admission Glasgow Coma Scale to Predict Aspiration Pneumonia in Poisoned Patients

Sebastien Champion and Vincent Spagnoli

Article Type: Short Commentary | First Published: August 01, 2017

Glasgow Coma Scale (GCS) assesses the need and guides tracheal intubation in trauma patients. GCS provides a practical method for assessment of impairment of conscious level in response to defined stimuli. GCS is the sum of 3 sub-scores for eye opening (1 to 4), verbal (1 to 5), and best motor (1 to 6) response to stimulations....

 Open Access DOI:10.23937/2378-2951/1410100

Why Cardiac Resynchronization Therapy (CRT) is Usually Prescribed along with Automatic Implantable Defibrillation (AID)? Is it a Sensible Decision? Historical Perspective

Max E Valentinuzzi

Article Type: Critical Review | First Published: July 26, 2017

The objective of this paper tries to answer the questions posed in the title, that is, why Cardiac Resynchronization Therapy (CRT) is usually prescribed along with Automatic Implantable Defibrillation (AID)? Is it a sensible decision? For that matter....

 Open Access DOI:10.23937/2378-3648/1410031

Deriving Transition Probabilities and Evolutionary Distances from Substitution Rate Matrix by Probability Reasoning

Xuhua Xia

Article Type: Review Article | First Published: July 27, 2017

Substitution rate matrices are used to correct multiple hits at the same sites, which requires the derivation of transition probabilities and evolutionary distances from substitution rate matrices. The derivation is essential in molecular phylogenetics and phylogenomics....