Open Access DOI:10.23937/2469-5823/1510082

Determination of Changes in the Brain in Bipolar Disorder by Imaging Methods and its Reflections in Nursing Care

Özlem Kaştan and Gülşah Acar

Article Type: Review Article | First Published: September 23, 2017

Bipolar disorder is a chronic brain disease characterized by lifelong repetition and remissions and emotional state fluctuations that vary from deep depression to extreme happiness. Although there are many studies on the neurobiological basis of bipolar disorder, its pathophysiology is not fully known....

 Open Access DOI:10.23937/2469-5823/1510081

Hepatitis E Virus Infection in a Student Healthcare Worker: A Case Report

Antoon De Schryver, Inge Wijnants, Paolo Bonanni, Ramona Hambach, Marc van Sprundel and Guido François

Article Type: Case Report | First Published: September 23, 2017

Against the background of hepatitis prevention and control in Belgium, an important focus is on healthcare and occupational medicine settings. Most Belgian healthcare workers in training are administered a combined hepatitis A/B vaccine by occupational health services. ...

 Open Access DOI:10.23937/2469-5807/1510061

Pancreatic Adenocarcinoma: Role of the Site-Specific of Metastases

Vitorino Modesto dos Santos and Lister Arruda Modesto dos Santos

Article Type: COMMENTARY | First Published: October 26, 2017

Pancreatic adenocarcinoma is a severe malignant condition with a median survival lower than one year, and a five-year survival rate of about 30%, including tumors resected at early stage. Recurrences within two years occur in up to 80% of the resected tumors. More than two thirds of advanced pancreatic adenocarcinomas have single site of metastases, mainly affecting the liver, lungs, bones and brain, by decreasing order of frequency....

 Open Access DOI:10.23937/2469-5807/1510060

Empty Sella and Sagittal Sinus Thrombosis in a Woman with Subaortic Stenosise

Vitorino Modesto dos Santos, Rafaela Pinheiro Weiber, Rosana Aparecida Rodrigues Cardoso, Mariely Fernanda da Silva Helbingen and Bruno César Rodrigues do Amaral

Article Type: Case Report | First Published: October 25, 2017

Cerebral venous thrombosis is not a frequent condition and may follow unsuspected, with unspecific manifestations. Neuroimaging studies are mandatory in differential diagnosis, which includes arterial strokes and other benign and malignant causes of intracranial hypertension, headaches, seizures, and hemiparesis....

 Open Access DOI:10.23937/2469-5807/1510059

Decrease of Nitrergic Innervation in the Esophagus of Patients with Chagas Disease: Correlation with Loss of Interstitial Cells of Cajal

Rodolfo Duarte Nascimento, Patrícia Rocha Martins, Jacqueline Garcia Duarte and Débora d'Ávila Reis

Article Type: Research Article | First Published: October 13, 2017

The pathogenesis of megaesophagus in chronic Chagas disease, which is caused by infection with the parasite Trypanosoma cruzi is compelling. Individuals with megaesophagus often present achalasia and disturbances of peristalsis and neuronal loss....

 Open Access DOI:10.23937/2469-5807/1510058

Malignant Melanoma Arising in Association with Sinonasal Melanosis: A Case Report and Review of the Literature

Eric Ewing, Jeffrey B Jorgensen, Benjamin F Erhardt and Lester J Layfield

Article Type: Case Report | First Published: September 02, 2017

Malignant melanomas of the nasal mucosa represent approximately 1% of all melanomas and reported examples often arise in areas of pigmentation of the nasal mucosa. Melanin pigmentation has been reported to occur in the nasal glands and dendritic cells but melanomas arising from areas of pigmented (melanocyte containing) nasal glands have not been reported to our knowledge....

 Open Access DOI:10.23937/2378-2951/1410105

The Heart Remembers: Anterior T wave inversions in a Patient with Intermittent Left Bundle Branch Block

Janaki Rami Reddy Manne

Article Type: Case Report | First Published: October 11, 2017

Even though the new onset of T wave inversions on the electrocardiogram is always an alarming finding, but they are not always pathognomonic of myocardial ischemia. Many cardiac and non-cardiac conditions have been described in association with T wave inversions on the electrocardiogram....

 Open Access DOI:10.23937/2378-2951/1410104

Giant Right Atrium or Ebstein Anomaly?

Hacer Kamalı, Abdullah Erdem, Cengiz Erol and Atıf Akçevin

Article Type: Case Report | First Published: October 09, 2017

Many acquired and congenital pathologies could cause enlargement of Right Atrium (RA). In rare pathologies we couldn't find an obvious reason for enlargement of RA. Sometimes it leads to misdiagnosis if we try to explain an unknown pathology with well known pathology....

 Open Access DOI:10.23937/2378-2951/1410103

Endothelial Function for Cardiovascular Disease Prevention and Management

Minako Yamaoka-Tojo

Article Type: Review Article | First Published: September 27, 2017

Endothelium is a layer of the endothelial cells lining to the lumen of blood vessels, lymphatic vessels, the heart and other organs. Vascular endothelium is considered to be the largest endocrine organ in human body. Its total weight is about 1.5 kg, and it is responsible for maintaining homeostasis of the living body by exerting various functions....

 Open Access DOI:10.23937/2378-2951/1410102

A Feasibility Pilot Study to Assess the Efficacy of NavX Guided Detection of Pulmonary Vein Electrograms during Atrial Fibrillation Ablation [NavX Guided Detection of Pulmonary Vein Electrograms]

Yaariv Khaykin, Pouria Alipour, Meysam Pirbaglou, Paul Ritvo, Zahra Azizi, Zaev Wulffhart, Bonnie Whaley, David Giewercer, Kellie Winger and Atul Verma

Article Type: Research Article | First Published: September 25, 2017

Pulmonary Vein Antrum Isolation (PVAI) targeting PV triggers is an established treatment for paroxysmal Atrial Fibrillation (AF). Ablation lesions are typically delivered around the entire circumference of each individual PV. This study tested a strategy where electrical inputs to the PVs were mapped using the NavX system and selectively targeted before ablation....