Open Access DOI:10.23937/2469-5769/1510129
Risk Factors for Lymph Node Metastases in Pediatric Differentiated Thyroid Cancer (DTC) - A Comprehensive Review
Vaia Karapepera, Michael Karanikas and Aliki Fiska
Article Type: Comprehensive Review | First Published: 2024/05/06
Differentiated Thyroid Carcinomas (DTC) constitutes a significant percentage of pediatric malignancies, presenting distinct histological and morphological differences from their adult counterparts. Pediatric DTCs exhibit greater aggressiveness, and are diagnosed at a more advanced stage than adult thyroid cancers, in many cases already having spread to the lymphatic system. This comprehensive review explores the risk factors for lymph node metastases (LNM) in pediatric DTC....
Open Access DOI:10.23937/2474-3631/1510038
A Retrospective Longitudinal Cohort Study: The Effect of Long-Term Use of Methadone and Associated Factors on QTc in a Maintenance Program
Julia MM Deuss, MD, Mandy MM Jansen, BSc, Monique CT Bongaerts, MD, Maurice Theunissen, PhD and Marieke HJ van den Beuken-van Everdingen, MD, PhD
Article Type: Research Article | First Published: 2024/05/05
Since the 1960s Methadone Maintenance Treatment (MMT) has led to a great improvement in health status and a decline in mortality among opioid-using patients. However, more awareness has been raised by professionals worldwide to the adverse effects and safety of MMT. This retrospective longitudinal cohort study aimed to investigate the effect of long-term use of methadone on the QTc interval in a population of MMT patients....
Open Access DOI:10.23937/2378-346X/1410151
Vision Therapy as an Early Intervention Approach in Autism Spectrum Disorder Associated with Down Syndrome: A Case Report
Nikhita Jacob, Sandhya K and Nidhi M
Article Type: Case Report | First Published: 2024/05/16
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by behavioural changes in oculo-visual, cognitive, and language factors. Down syndrome (DS) impacts visual acuity and contrast sensitivity, often manifesting sensory deficits of optical or neural origin. Early identification and a multidisciplinary treatment approach are crucial for both conditions. This case aims to explore the efficacy of vision therapy in improving eye movements in a patient with ASD associated with...
Open Access DOI:10.23937/2377-9004/1410258
Adnexal Torsion and Epiploic Appendigitis in Pregnant Women: Case Report
Oumayma Ben Rejeb, Amal Bayar, Cyrine Chelly, Wessim Elouni and Sassi Boughizane
Article Type: Case Report | First Published: 2024/05/15
Adnexal torsion is a surgical emergency that cannot be ignored in women. It is a diagnostic and therapeutic challenge. While the occurrence of adnexal torsion in pregnant women is rare, it still can present significant risks. We present the case of a 23-year-old woman, pregnant at 24 weeks of amenorrhea and consulted for an acute abdominal pain. She underwent exploratory laparoscopy, which revealed ovarian torsion caused by a functional cyst along with epiploic appendigitis. During the procedure...
Open Access DOI:10.23937/2469-5750/1510126
Sweet Syndrome Induced by AFINITOR: Case Report
Edgar Bedang Mone Keby da Costa, El khalil El Bakali, Papys Mendes, Youssef Zemmez, Rachid Frikh and Naoufal Hjira
Article Type: Case Report | First Published: 2024/05/13
This is the most common neutrophilic dermatosis and the prototype of superficial dermal acute neutrophilic dermatoses. Its incidence is rare. Sweet's syndrome predilection is for adults aged 30 to 50, but children have also been reported. There is a female predilection [1]. It is distributed worldwide, with no racial predilection. The typical picture is of a sudden-onset rash, accompanied by high fever and neutrophilic leukocytosis [2]. Recombinant granulocyte-colony stimulating factor (G-CSF) h...
Open Access DOI:10.23937/2572-3286/1510095
Magnitude of Metabolic Syndrome and its Associated Factors among Patients with Chronic Kidney Disease: Laboratory-Based Cross-Sectional Study in Northwest Ethiopia
Melaku Mekonnen Agidew, Awgchew Behaile Teklemaryam, Misganaw Asmamaw Mengstie, Addisu Melake Bayafers, Zelalem Tilahun Muche, Ediget Abebe Zewude, Teklie Mengie Ayele, Achenef Bogale Kassie, Nega Dagnaw, Muluken Walle, Kefale Mitku, Aklesya Enkobahry Haileslassie and Anemut Tilahun Mulu
Article Type: Original Article | First Published: 2024/05/11
Chronic kidney disease (CKD) is a non-communicable disorder that causes a progressive decline in kidney function, leading to complications such as metabolic disorders that can increase the risk of heart diseases. Metabolic syndrome (MetS) is a significant global health issue characterized by a combination of factors like high blood pressure, central obesity, abnormal lipid levels, and elevated blood sugar levels. As such, this research conducted in Northwest Ethiopia sought to determine the prev...
Open Access DOI:10.23937/2378-3648/1410056
Lack of Association of Mitochondrial tRNA(Leu) A3243G Mutation with Allergic Chronic Rhinosinusitis Pathogenesis in South Indian Population
Raja Meghanadh Koralla, Sunita G Kumar, Santoshi Kumari Manche, Jujjuvarapu Venkata Ramakrishna, Shehnaz Sultana, Madhavi Jangala and Pardhananda Reddy Penuguluru
Article Type: Original Research | First Published: 2024/05/11
The association between genetic variants and respiratory conditions such as allergy and chronic rhinosinusitis has been the subject of extensive research. While the mitochondrial tRNA A3243G mutation has been extensively studied in the context of mitochondrial disorders, its potential role in inflammatory conditions such as allergy and chronic rhinosinusitis is not as well understood. In this study, we aim to explore and understand the potential link between the mitochondrial tRNA A3243G mutatio...
Open Access DOI:10.23937/2377-9004/1410257
Uterine Rupture at 17 Weeks of Amenorrhoea in a Septate Uterus: A Desperate Case Report
Ouattara Adama, Ouédraogo Emmanuel, Cissé Maria, Traoré Salah Idriss and Ouédraogo Charlemagne Marie
Article Type: Case Report | First Published: 2024/05/13
A septate uterus is the most common congenital anomaly of the uterus. Pregnancy in a septate uterus may progress asymptomatically to term. However, complications may arise and threaten the obstetrical or even vital prognosis of the pregnant woman. The authors report a rare case of uterine rupture in the second trimester of pregnancy in a septated uterus....