Open Access DOI:10.23937/2474-3658/1510110
Dog Scratch Fever Secondary to Capnocytophaga Species in a Patient Without Risk Factors
Linda C Klumpp, MD, Gustine Liu-Young, MD, James Craig, MD, Leonard Hamera, MD, Jeffrey Jordan, MD, Srinivas Dantuluri, DO and Sunoj Abraham, MD
Article Type: Case Report | First Published: February 12, 2020
Capnocytophaga is a rare bacteria found in the saliva of canines. C. canimorsus is present in the oral cavity of 67-86% of dogs. In vitro growth requires specialized media. Patients who are immunocompromised are at greatest risk for infection. There are no clinical trials examining the duration of antibiotics. Capnocytophaga species is a very rare fastidious, slow growing gram negative rod found in the saliva of canines and felines. It belongs to the genus flavobacteriacea, a capnophilic faculta...
Open Access DOI:10.23937/2474-3658/1510109
Aeromonas Hydrophila Infection in an Immunocompetent Patient Leading to Necrotizing Fasciitis
Asish Regmi and Pushpa Khanal
Article Type: Case Report | First Published: February 10, 2020
We present to you the case of 77 YO female with PMH of DM, A fib and recent H/O ascending cholangitis and cholecystectomy complicated by ruptured gallbladder with bile peritonitis and JP drain placement. After the discharge she was having diarrhea and was tested positive for C diff and was started on oral vancomycin. Almost about 2 weeks after the discharge she started to develop sudden onset of right leg pain, because of that she was taken to the ED of outside hospital where there was a suspici...
Open Access DOI:10.23937/2469-5718/1510157
Systematization of Functional Training Sessions to Benefit Physical Fitness for Daily Activities in Older People
Antonio Gomes de Resende-Neto and Marzo Edir Da Silva-Grigoletto
Article Type: Editorial | First Published: February 10, 2020
Tools applied today in the Functional Training (FT) have long been used in general fitness programs, but systematic use and scientific interest are recent phenomena. Thus, there are many methodological conflicts and divergences in the prescriptions of this method. For example, some studies have associated FT with the use of instability in many exercises, while others use unstable bases in a small portion of training, or simply do not use. Thus, there is still an absence of a systematic FT model ...
Open Access DOI:10.23937/2378-3419/1410132
A Novel Combined Methodology for Isolation and Detection of Circulating Tumor Cells based on Flow Cytometry and Cellular Filtration Technologies
Nikolaos G Grigoriadis, Konstantinos A Kyritsis, Melpomeni G Akrivou, Lefki-Pavlina N Giassafaki and Ioannis S Vizirianakis
Article Type: Original Article | First Published: February 08, 2020
Cancer cell presents a dynamic nature that evolves over time in its microenvironment through a complicating molecular and cellular interaction network. Despite the progress already achieved in the imaging technologies and the molecular tools used for tumor cell diagnosis and treatment approaches, metastasis still remains a major hindering factor that limits clinical outcomes. Circulating tumor cells (CTCs) present the potential in providing critical information to understand the metastasis proce...
Open Access DOI:10.23937/2378-3419/1410131
Palmoplantar Erythrodysesthesia Associated with Capecitabine, Epidemiological Mapping and Risk Factors in Morocco
Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui
Article Type: Brief Reports | First Published: January 27, 2020
A prospective cohort of a descriptive and analytical study, including sixty-one cases of Palmoplantar erythrodysesthesia in patients treated with capecitabine. The objective of this study is to determine an epidemiological mapping of Palmoplantar erythrodysesthesia in cancer patients on capecitabine treatment and to identify possible risk factors. The incidence of PPE was 64%. The median age of the patients who developed PPE was 54 years. 70% of the cohort was female, breast neoplasia represente...
Open Access DOI:10.23937/2378-3419/1410130
Hyperpigmentation Associated with Anti-Tumor Chemotherapy: A Series of 54 Cases, Demo-Topographic Aspects and Interest of the Dermatological Intervention
Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui
Article Type: Case Series | First Published: January 27, 2020
Three-year prospective study, from April 2016 to May 2019, including patients followed in oncology for malignant neoplasia, who developed hyperpigmentation following the start of antitumor chemotherapy for digestive, mammary and hematologic neoplasms, including the following molecules: 5 Fluorouracil, Tegafur, Cyclophosphamides, and Doxorubicin, in an isolated or combined mode. The study enrolled 54 patients, with an average age of 48 years and extremes ranging from 22 years to 67 years, with a ...
Open Access DOI:10.23937/2469-5866/1410033
Late-Life Alzheimer's Disease (AD) Detection Using Pruned Decision Trees
Gopi Battineni, Nalini Chintalapudi and Francesco Amenta
Article Type: Original Research | First Published: February 08, 2020
Machine Learning (ML) is a contemporary technique of artificial intelligence. These methods are exponentially rising in the medical field, especially in diagnosis and disease predictions. The present study was aimed to develop a decision tree model to predict late-life Alzheimer’s disease (AD). A dataset of 150 subjects along with 373 MRI sessions demographic values were considered in this paper. Pruned decision trees (J48) were employed to do predictive analysis on AD subjects. Model validati...
Open Access DOI:10.23937/2378-3656/1410296
Mixed Zone between Drug-Induced Hyperpigmentation and Generalized Fixed Pigmented Erythema
Tarik Hanafi, Amine Essaoudi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui
Article Type: Case Report | First Published: January 31, 2020
We report a particular case of fixed drug eruption (FDE), in its erythematous and pigmented form, as a fixed pigmented erythema (FPE), which manifests in a generalized form, evolving for three years, and discuss the imputability to piroxicam and the Ramipril/Hydrochlorothiazide combination. Indeed, chronological, semiological, bibliographic criteria, were imprecise and non-discriminatory. We ended up retaining the diagnosis of fixed pigmented erythema (FPE) of particular diffuse presentation ind...
Open Access DOI:10.23937/2378-3656/1410295
Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa in an HIV-Positive Patient
Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui
Article Type: Case Report | First Published: January 27, 2020
Hidradenitis Suppurativa (HS), also called Acne inversa, is a Chronic inflammatory, suppurative, fistulizing disease, with a risk of malignant degeneration to squamous cell carcinoma (SCC). We report an intriguing case of a patient who developed an aggressive form of HS within a very short time of nine years, indeed, the patient was infected with the human immunodeficiency virus (HIV) and human papilloma virus (HPV). We believe that the oncogenic role of HPV was increased, given the very fast de...