Open Access DOI:10.23937/2469-567X/1510069
Virologic Response among Key Populations Living With HIV following a Switch to Dolutegravir-Based Regimen in Southern Nigeria
Moses Katbi, Adefisayo O Adedoyin, Maryam Bello, Adeoye Adegboye, Oluwatosin Adeoye, Abiye Kalaiwo, Kent Klindera, Iyiola Faturiyele, Tolu Alamu, Homsuk Swomen, Bartholomew Ochonye, Michele Russell, Abdulmalik Abubakar and Babatunji Odelola
Article Type: Original Research | First Published: September 05, 2020
Achieving optimal virologic suppression among key population groups is essential to HIV epidemic control. The recommendation to transition HIV positive key populations from efavirenz-based regimen (Tenofovir, Lamivudine, Efavirenz (TLE)) to dolutegravir-based regimen (Tenofovir, Lamivudine, Dolutegravir (TLD)) considered the effectiveness of dolutegravir in achieving suppressed viral loads within a short period of time. The aim of this study was to investigate the virologic outcome of key popula...
Open Access DOI:10.23937/2469-5734/1510112
Influence of Retention Procedures on the Percentage of Occlusal Loads for Single Implant-Supported Crowns and Tooth-Supported Crowns
Gao Wu, DDS, Lizong Liang, DDS, Jie Ran, DDS and Jianxiang Tao, PHD
Article Type: Research Article | First Published: August 31, 2020
The purpose of this study was to investigate the influence of retention procedures on the percentage of occlusal loads experienced by single implant-supported crowns and tooth-supported crowns within the mouths of carefully selected human test subjects. Thirty subjects were selected: 20 received a single implant and full crown restoration; and 10 received a single crown restoration on a natural tooth. The percentage of occlusal loads on crowns was recorded before and after cementation or after h...
Open Access DOI:10.23937/2378-2951/1410200
Therapeutic Strategy for a Patient with Advanced Heart Failure and Schizophrenia without Cardiac Replacement Therapies
Masakazu Hori, MD, Teruhiko Imamura, MD, PhD, Makiko Nakamura, MD, PhD, Masaki Nakagaito, MD, PhD and Koichiro Kinugawa, MD, PhD
Article Type: Case Report | First Published: September 03, 2020
Despite considerable improvement in the cardiac replacement therapy including durable left ventricular assist device and heart transplantation, some patients are not good candidates for such intensive therapies given their comorbidities. We had a 58-year-old patient with advanced heart failure who was assigned to INTERMACS profile 2 with progressive end-organ dysfunction refractory to inotropes. Following the detailed discussion, he decided not to receive cardiac replacement therapy dominantly g...
Open Access DOI:10.23937/2378-2951/1410199
Multi-Modality Imaging of a Case of Multiple Intra-Cardiac Aneurysms Complicated by Mitral Valve Leaflet Perforation
Ruchika Meel, PhD, Liam Lorentz, FCRAD, Ricardo Goncalves, Bongane Ngutshane, MD and Shungu Mogaladi, MMED
Article Type: Case Report | First Published: September 03, 2020
Intra-Cardiac aneurysms are a rare entity. In the past case reports and series have described the entity of "annular sub-valvular left ventricular aneurysms" in patients of African descent. These authors proposed the aforementioned aneurysms to be of congenital aetiology. Majority of the time the aneurysms were located in the sub-mitral or sub-aortic positions and were diagnosed by echocardiography and ventriculography. Multiple discrete left ventricular aneurysms complicated by mitral valve per...
Open Access DOI:10.23937/2378-2951/1410198
Primary Percutaneous Coronary Intervention (pPCI) Using Right Fossa Radialis (Dorsal Transradia) Approach
Santosh Kumar Sinha, Puneet aggarwal and Umeshwar Pandey
Article Type: Case Report | First Published: August 31, 2020
Haematoma, dissection, local site granuloma, and persistent radial artery occlusion are few of the complications of conventional transradial access. The distal radial artery located in the fossa radialis or anatomical snuffbox on the dorsal side of the hand may be an attractive alternative to conventional radial stick. Here, we report a case of a 47-year-old diabetic male who presented with retrosternal chest pain and sweating of 2-hours duration, and diagnosed as acute inferior wall myocardial ...
Open Access DOI:10.23937/2469-5696/1410056
Laboratory Blood Coagulation in Sudanese with Falciparum Malaria: A Glance of Change Outcomes
Bashir Abdrhman Bashir and Mohamed Seed Ahmed
Article Type: Original Research | First Published: September 03, 2020
Malaria is a potentially life-threatening disease caused by infection of erythrocytes with one of five different types of protozoan parasites of genus plasmodia. Falciparum species is an aggressive type associated with multiple alterations in hemostasis. A cross-sectional descriptive study was undertaken to screen the effect of malaria infection on coagulation test results in adults with the falciparum malaria parasite. Forty- eight consecutive adults with falciparum malaria were studied along w...
Open Access DOI:10.23937/2690-263X/1710006
Haematological Changes in Alcohol and Substance Use Disorders- An Overview
Raka Jain, Aishwariya Brigit George and Shubham Narnoli
Article Type: Mini Review | First Published: August 31, 2020
Alcohol and Substance use remains a worldwide social problem. There is an increasing awareness that alcoholics and substance abusers do show some haematological abnormalities (e.g., hemoglobin, white blood cells count, mean corpuscular volume, mean corpuscular haemoglobin concentration, red blood cells count, hematocrit). Consequences of these haematological abnormalities can result in serious medical complications. The aim of this paper is to present an overview of haematological changes in alc...
Open Access DOI:10.23937/2643-4466/1710027
A Potential Non-Invasive Therapy to Treat COVID-19, As Yet Unrecognized in the Medical Literature
Benjamin J Scherlag, PhD, Ronald A Scherlag, BS, MBA and Sunny S Po, MD, PhD
Article Type: Commentary | First Published: September 05, 2020
As the pandemic rages across the globe, we await the proven safe and effective vaccine that will turn the tide against the novel coronavirus SARS-CoV-2 (a.k.a. COVID-19) spread. In the meantime, a number of pharmaceutical agents have been the subject of studies including, Hydroxychloroquine, Remdesivir, Dexamethasone, among others with varying degrees of clinical efficacy. Hidden from the medical literature is the evidence gathered by investigators for more than a decade that negative air ions c...
Open Access DOI:10.23937/2378-3656/1410317
Acute Upper Limb Ischemia in a Patient with COVID-19 Pneumonia
Roaa Alosaimi, MD, Ahood A Albajri, MD and Roaa M Albalwi, MD
Article Type: Case Report | First Published: August 31, 2020
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped RNA beta coronavirus. It is a novel coronavirus responsible for the current global pandemic and poses a critical threat to global health worldwide. While SARS-CoV-2 is known to cause significant pulmonary disease, including pneumonia and acute respiratory distress syndrome (ARDS), clinicians have observed many extrapulmonary manifestations of COVID-19 particularly thrombosis...
Open Access DOI:10.23937/2572-4061.1510034
Psychological Impact of Medical Professionals Handling COVID-19 Patients in Hospitals
Anirban Biswas, Saroni Biswas and Arijit Bhowmik
Article Type: Research Article | First Published: August 22, 2020
COVID-19 pandemic became a death troll and cause of unbearable psychological pressure for all and the pandemic situation has been considered as a national disaster in India. Present study identified the mental health status of the medical professionals in different hospitals handling COVID-19 patients. We collected psychological data of medical professional using online questionnaire and identified their psychological status following three tools namely, Generalized Anxiety Disorder (GAD), Depre...