Open Access DOI:10.23937/2469-5807/1510118
Prevalence of Incidental Thyroid Nodules at Necropsies Performed at a Division of Postmortem Inspection in Brazil
Gilberto Mendes Menderico Jr, PhD, MD, Leonardo Salgado Alves, MD, Layla Riva Ismail, MD, Pedro Estefan Otaviani Bernis, MD, Larissa Cichello Benassi, MD, and Rodrigo Lopes Pessoa da Silva, MD
Article Type: Original Article | First Published: March 08, 2021
Thyroid nodules are prevalent in the general population, especially in women and the elderly. Often, the diagnosis of nodular lesions is incidental, representing a very common finding, and usually these lesions are not clinically important since few of them carry a malignant neoplasm. Despite the low incidence of malignancy, it is imperative to exclude the presence of thyroid carcinoma. This report aims is to identify the prevalence of thyroid nodules in the population of Baixada Santista (a geo...
Open Access DOI:10.23937/2469-5734/1510127
Oral Biofilm and Its Impact on Oral Health, Psychological and Social Interaction
Gedif Meseret Abebe
Article Type: Review Article | First Published: March 12, 2021
Oral health can be act as “mirror” that indicate and reflect the overall health condition, life style and oral hygiene. Oral cavity harbours arrays of microorganisms that interact with diet, oral environment, and host. This complex dynamic interaction results in microbial colonization and the subsequent oral biofilm formation. Oral biofilms are highly ordered, surface-associated assemblages of microorganisms embedded in an extracellular matrix. These surface-attached microbial communities ar...
Open Access DOI:10.23937/2378-346X/1410124
Pars Plana Vitrectomy for Symptomatic Vitreous Floaters: Another Look
Tayab C Waseem, PhD, Evan R DaBreo, MD, Jiang Douglas, MS, Yousef Hasanzadah, BS, Rebecca Clawson, BS, Alan L Wagner, MD, FACS and Kapil G Kapoor, MD, FACS
Article Type: Original Research | First Published: March 22, 2021
Historically, pars plana vitrectomy (PPV) has been considered a controversial treatment for elective removal of primary symptomatic vitreous opacities (floaters) due to the possibility of extreme and even blinding side effects of the procedure. The purpose of this study is to determine the safety and patient satisfaction level for those who undergo PPV for removal of vitreous floaters. This was a retrospective study of 54 eyes in 51 patients (average age 68) who underwent 23 gauges PPV between 2...
Open Access DOI:10.23937/2378-3001/1410108
Multiple Mononeuropathy in Churg-Strauss Syndrome Presenting as a Subacute Ascending Polineuropathy: A Case Report
Michele Pistacchi, Manuela Gioulis, MD, Sergio Ferrari, MD, Tiziana Cavallaro, MD and Sandro Zambito Marsala, MD
Article Type: Case Report | First Published: March 13, 2021
Multiple mononeuropathy is not unusual in Churg-Strauss Syndrome. Presenting symptoms may be subacute and the differential diagnosis became complicated, particularly when neuropathy is the sole manifestation of disease. We report a clinical case of an adult man hospitalized complaining symptoms of subacute neuropathy successively recognized as multiple mononeuropathy. Histological examination of sural nerve showed the evidence of systemic necrotizing vasculitis with eosinophils infiltration, con...
Open Access DOI:10.23937/2643-3885/1710052
Use of a Second Ray Amputation for Foot Salvage in a Collegiate Athlete with Proteus Syndrome
Ethan R Harlow, MD, Pranav Khambete, BS, Jason Ina, MD, and Shana Miskovsky, MD
Article Type: Case Report | First Published: February 22, 2021
Our patient is a 20-year-old female, NCAA Division II collegiate soccer player, who presented to the office with progressive deformity and pain of the right foot and second toe that has been worsening over one year. At age 5, she was diagnosed with PS with the right foot overgrowth as the presenting symptom. Her symptoms progressed to the point where prolonged standing would cause her pain and thus rendered her unable to continue her athletic endeavors, limited her shoe wear, and began to affect...
Open Access DOI:10.23937/2378-3419/1410148
Metastatic Tfe3-Overexpressing Renal Cell Carcinoma: Case Report and Literature Review
Paulo Victor Zattar Ribeiro, Leonora Zozula Blind Pope, Beatriz Granelli, Milena Luisa Schulze, Andréa Rodrigues Cardovil Pires and Mateus da Costa Hummelgen
Article Type: Case Report | First Published: March 19, 2021
Renal cell carcinoma (RCC) associated with Xp11.2 translocation/TFE3 gene fusion (Xp11.2 RCC) is a rare subtype of RCC which is delineated as a distinct entity in the 2004 World Health Organization renal tumor classification. To highlight a rare case, with few publications on the topic, in addition to providing scientific explanations about it. This is a case report of a 58-year-old white male with the diagnosis of renal clear cell carcinoma (RCC). The immunohistochemistry was performed and show...
Open Access DOI:10.23937/2378-3419/1410147
Triple Chemotherapy (DOX) in Patients with Advanced Gastro- Esophageal Adenocarcinoma - A Phase II Study
Tarpgaard LS, Jensen M, Schønnemann KR, Jensen HA, Yilmaz M and Pfeiffer P
Article Type: Original Research | First Published: March 19, 2021
Triple chemotherapy improves efficacy in patients with advanced gastro-esophageal (GE) cancer. In a phase I dose- finding trial including 23 patients we established a recommended dose of triple chemotherapy with docetaxel (D), oxaliplatin (O), and capecitabine (X) (DOX). We found promising activity and here we present efficacy data from the succeeding phase II trial. Patients and Methods: All patients had histologically confirmed GE adenocarcinoma. Therapy was docetaxel (51 mg/m2 as a 60 minutes...