Open Access DOI:10.23937/2469-5718/1510187
First Rib Fracture Nonunion Treated With Bone Marrow Aspirate Concentrate in a Division 1 Collegiate Baseball Player
Kanjiya S, Gambardella RA and Moon CN
Article Type: Case Report | First Published: April 17, 2021
Fractures of the first rib have historically been described in major trauma with a high prevalence for cardiothoracic and musculoskeletal fractures. However, there have been several case reports describing first rib fractures in athletes. The vast majority of these patients return to play with conservative management. Unfortunately, some patients may develop fracture nonunion. Patients that develop a nonunion may remain asymptomatic. In the rare case that a patient is symptomatic or develops tho...
Open Access DOI:10.23937/2378-3516/1410152
Efficacy of Initial Large-Volume Thoracentesis for Malignant Pleural Effusions
Victor E Prado, MD, Shasha X Chen, MD, Shashvat Sukhal, MD, Sean B Smith, MD and Sanjay A Patel, MD
Article Type: Research Article | First Published: March 31, 2021
Large malignant pleural effusions (MPE) are common and can cause respiratory distress. Large-volume thoracentesis (LVT) is the most readily available initial procedure, but its efficacy for large MPE with acute respiratory symptoms is unknown. We reviewed LVT for MPE causing ≥ 50% opacification of the hemithorax who presented with acute respiratory symptoms. LVT was defined as draining ≥ 1.5 liters (L). We catalogued volume removed and percent opacification of the hemithorax after LVT in ord...
Open Access DOI:10.23937/2378-3516/1410151
Extensive Pneumomediastinum in COVID-19 Pneumonia
Adetiloye Oluwabusayo Adebola, MD, Beketova Tatyana, MD, Williams Tabatha, NP and Agarwal Sanket, MD
Article Type: Case Report | First Published: March 31, 2021
Pneumomediastinum, defined as the presence of air in the mediastinum often occurs due to trauma, mechanical ventilation or surgical procedure. It may also occur spontaneously due to predisposing lung diseases such as asthma and Chronic obstructive pulmonary airway disease (COPD). In this report, we present a case of a patient with COVID-19 pneumonia without any underlying lung conditions or usual risk factors for pneumomediastinum who developed extensive pneumomediastinum with pneumopericardium ...
Open Access DOI:10.23937/2378-3516/1410150
Incidence of Post-Procedural COVID-19 at an Urban Academic Medical Center during High Prevalence Months
Joanne Szewczyk, MD, Dao M Nguyen, MD, MSc, Prem R Warde, MSIE, Bhavarth Shukla, MD, MPH, Tanira Ferreira, MD, Dipen J Parekh, MD and Hayley B Gershengorn, MD
Article Type: Research Article | First Published: March 31, 2021
In the beginning of the pandemic, after elective procedures resumed in Florida, we tested all patients for COVID-19, nasal pharyngeal swab PCR 72 hrs prior to any procedure. We conducted a retrospective cohort to see the incidence of COVID-19 post-procedural. We conducted a retrospective cohort study of all adult cases of same day or hospital-based procedures at the University of Miami Hospital and Clinics from April 1-September 23, 2020 who were COVID-19-negative (by SARS-CoV-2 polymerase chain...
Open Access DOI:10.23937/2378-3516/1410149
Etiology of Pleural Effusion among Adults in Three University Hospitals in Beirut: A One-Year Retrospective Cross Sectional Analytical Study
Ali IBRAHIM, Amrou RIDA, Ibrahim MALASS and Loubna Tayara
Article Type: Research Article | First Published: March 31, 2021
Pleural effusion, the pathological accumulation of fluid in the pleural space, is very common. It has a wide differential diagnosis, and a delayed etiological diagnosis can be associated with markedly higher morbidity and mortality. It is divided into two main types: Transudative and Exudative, depending on the mechanism of fluid accumulation. The most common causes of pleural effusion are: Congestive heart failure, infections, malignancy, liver and kidney failure. Thoracentesis may be indicated...
Open Access DOI:10.23937/2643-4571/1710029
Defining a Growing and Maturing Skeleton and its Relevance in Diseases that Affect Skeletal Growth, Such as X-Linked Hypophosphataemia (XLH)
Signe Beck-Nielsen, Nella Augusta Greggio and Lars Hagenӓs
Article Type: Review Article | First Published: April 17, 2021
The human skeleton is composed of bone, a living tissue that undergoes constant development throughout life. It is well established that changes in bone metabolism during the developmental stages of growth, modelling and remodelling determine long-lasting physiological parameters, such as final height achieved, peak bone mass, bone quality and bone health. A complex interplay of environmental, genetic, nutritional, physiological and behavioural factors plays a role in these processes. These modi...
Open Access DOI:10.23937/2643-4563/1710028
On the Impact of Premature Termination of Chemotherapy on Relapse of Breast Cancer
Heidrun Männle, Karsten Münstedt, Felix Momm and Jan Willem Siebers
Article Type: Original Article | First Published: March 15, 2021
Some breast cancer patients receive a recommendation for adjuvant chemotherapy if necessary. In some cases, patients refuse this recommendation. In other cases, they start with chemotherapy, but then discontinue it. The question raised here are the effects of patients’ rejection or premature termination of recommended chemotherapies. 1916 patients, who received a recommendation for chemotherapy, were analyzed between 1997 and 2017. The analyses included descriptive analyses and Kaplan- Meier s...