Open Access DOI:10.23937/2469-5718/1510197

Reevaluation of Diagnostic Criteria for Exertional Rhabdomyolysis in Collegiate Wrestlers: A Case Series and Review

James Geiselman, DC, MS, DACBN, CCSP, ICSC, CES, CNC, NREMT, EMT-P and R. Darin Thomas, DO, MS

Article Type: Case Series | First Published: August 09, 2021

Rhabdomyolysis is a common and potentially fatal condition encountered by athletic trainers, coaches, primary care physicians and sports medicine physicians. Benign, or physiological, Exertional Rhabdomyolysis (ER) may resemble Delayed Onset Muscle Soreness (DOMS) and becomes clinically significant when accompanied by other morphologies including severe muscle pain and swelling, and myoglobinuria. ER is often characterized by a triad of symptoms including 1) Muscle pain, 2) Muscle swelling, and ...

 Open Access DOI:10.23937/2378-346X/1410128

Effectiveness of Topical Chemotherapy in Pigmented and Squamous Lesions of the Ocular Surface: Literature Review

Alejandra Lozano Bustillo, Mariel Eunice Amador-Rosa and Rocío Mitchell Banegas Erazo

Article Type: Review Article | First Published: July 31, 2021

The standard of care for the treatment of ocular surface lesions seems to have changed from surgery to topical chemotherapeutic agents as supplements to it or even as sole therapy, despite the scarcity of long-term studies in the published literature. A search in the academic search engines of PubMed, Google academic and Cochrene, of articles published in English language from the years 1997 to 2020 on chemotherapeutic management of ocular surface diseases. Topical or perilesional chemotherapy a...

 Open Access DOI:10.23937/2378-3001/1410113

Small Fiber Neuropathy Associated COVID-19: A Common or Uncommon Complication?

Milena Luisa Schulze, Letícia Caroline Breis and Marcus Vinícius Magno Gonçalves, MD, PhD

Article Type: Non-Systematic Review | First Published: August 05, 2021

The spectrum of neurological manifestations of COVID-19 range from anosmia and dysgeusia to myopathy and encephalitis. With the persistence of COVID-19 pandemic and the increase of infected subjects, new acute manifestations and sequels are being discovered. Lately, a new important neurological complication has been reported: Small Fiber Neuropathy (SFN). The existing literature reports cases of dysautonomia, orthostatic intolerance, and hyperesthesia manifestations, until the moment. Several ne...

 Open Access DOI:10.23937/2377-3634/1410146

Oral Semaglutide: A Novel Oral Preparation of GLP-1 Receptor Agonist

Priya Mohan Babu and Vinay Eligar

Article Type: Review Article | First Published: August 07, 2021

The glucagon-like peptide-1 (GLP-1) is an endogenous hormone produced by the L cells in the intestine. It is released in response to the intake of food and intestinal dilatation. It stimulates the pancreatic beta-cell to secrete insulin which is dependent upon ingestion of food. GLP-1 acts to slow down gastric motility and suppress appetite through the GLP-1 receptors in the satiety center. It is neutralized by the dipeptidyl peptidase-4 (DPP-4) enzyme very quickly. Hence the endogenous GLP-1 ha...

 Open Access DOI:10.23937/2377-3634/1410145

Effect of Educational Intervention Programme on Self- Management Practices of Individuals with Type 2 Diabetes Mellitus in South-East, Nigeria

Christiana Nkiru Okafor, PhD, Pauline Ojinaka Ezenduka, PhD, Chinedu Charles Onyenekwe, PhD, Kenneth Umezulike Ani, BMR (PT), M.Sc, Chika Chioma H Odira, PhD, Adaobi Maryann Ibekwe, PhD and Vera Ijeoma Onyekaonwu, M.Sc

Article Type: Original Research Article | First Published: July 31, 2021

Diabetes mellitus (DM) is a chronic disease that has great impact on health and affects quality of life of DM sufferers. Despite its chronic nature, DM is also a self managed disease that requires adequate knowledge of DM self management, in order for the sufferers to actively participate in their self care. The study was aimed at determining the effect of educational intervention programme on the selfmanagement practices of persons with type 2 diabetes (T2DM) in South East, Nigeria. A quasi ex...

 Open Access DOI:10.23937/2474-3674/1510126

COVID-19 Pneumonia: Guiding the Decision to Intubate Based on Work of Breathing Assessment Independent of Oxygenation

Amin Nadeem, Philip Fanapour, Mylene Apigo, Sunyoung Kim, Sanish George, Muhammad Khan, Azib Shahid, Charmi Patel, Ria Carnate and Raúl J Gazmuri

Article Type: Original Article | First Published: August 04, 2021

In most patients, COVID-19 pneumonia initially causes significant hypoxemia but without substantial impairment of lung compliance that would increase the work of breathing (WOB). Once adequate oxygenation is established, a tool to determine WOB independent of oxygen needs can guide the decision to intubate for invasive mechanical ventilation (IMV). We monitored oxygen requirements and WOB in 10 patients admitted with severe COVID-19 pneumonia (radiographic evidence of extensive lung disease with...

 Open Access DOI:10.23937/2469-5866/1410038

Long-Term Survival (23 Years) in a 26-Year-old Male after Antineoplaston Therapy for a Progressive, Diffuse Intrinsic Pontine Glioma: A Case Report

Stanislaw R. Burzynski, Gregory S. Burzynski, Tomasz Janicki and Samuel Beenken

Article Type: Case Report | First Published: August 08, 2021

Individuals suffering from diffuse intrinsic pontine glioma (DIPG) face a dismal prognosis with a median overall survival of approximately 11 months, and a 2-year survival rate of 10%. Long-term survival is very rare. To date, radiotherapy remains the standard of care at diagnosis, but offers a survival benefit of approximately 3 months. Chemotherapy has not shown to be effective. There is no Standard of Care for progressive DIPG after radiation therapy (RT). The purpose of this case report is t...

 Open Access DOI:10.23937/2377-4630/1410123

Comparison of the Effects of Target-Controlled Propofol Infusion and General Anesthesia with Desflurane on Postoperative Cognitive Functions in Controlled Hypotensive Anesthesia

Ayse Altun Gezgel, Fatih Dogu Geyik, Yucel Yuce, Ibrahim Gezgel, Banu Cevik and Kemal Tolga Saracoglu

Article Type: Clinical Study | First Published: August 13, 2021

We evaluated anesthesia depth, cerebral oxygenation and postoperative cognitive functions with NIRS and BIS monitoring and Mini-Mental State Examination (MMSE) score. We studied 60 patients with American Anesthesiologists Association (ASA) I-II, over 18 years of age, with a preoperative MMSE test score of 23 and above. Hemodynamic parameters, BIS and bilateral NIRS values were recorded. The mean arterial pressure (MAP) value was kept between 55-65 mmHg. MMSE test was repeated 1 hour before and 2...

 Open Access DOI:10.23937/2643-4512/1710060

Supporting the Frontline Workers during COVID-19 Pandemic: The Role of Non-Clinicians and Lessons Learned

Bhavana K, MD, Puneet Khanna, MD and Abhishek Singh, MD

Article Type: Short Communication | First Published: August 05, 2021

In a population of health care workers with a soaring level of burnout, this pandemic had the effect of rubbing salt to wound. The frontline workers were not only required to take this extra load, but their numbers had dwindled by illness, quarantine, and death. Though most of the focus during the pandemic has been related to clinical information, morbidity, mortality, and treatment strategies, there have been only a few reports highlighting the critical roles played by organizational leaders wh...

 Open Access DOI:10.23937/2572-407X.1510024

The Incidence and Predictors of Poor Glycemic Control among Adults with Type 2 Diabetes Mellitus in Ambulatory Clinic of Mettu Karl Referral Hospital, South Western, Ethiopia: A Prospective Cross Sectional Study

Gudisa Bereda and Gemechis Bereda

Article Type: Research Article | First Published: August 11, 2021

Diabetes mellitus refers to a grouping of metabolic diseases involving prolonged hyperglycemia caused by the inadequate secretion of insulin, poor insulin action, or a combination of the two. Poor glycaemic control is a major public health problem among patients with type 2 diabetes mellitus. To expose the incidence and predictors of poor glycemic control among adults with type 2 diabetes mellitus in ambulatory clinic of Mettu Karl Referral Hospital. An institutional based prospective cross-sect...