Open Access DOI:10.23937/2469-5769/1510141

Haemoglobin Profile of Newborns Using the SC Haemotype Test at the Kpalimé Prefectural Hospital Centre, Togo

Mawouto Fiawoo, Mensa Amblasso, Hèzouwè Magnang, Mazama Pakoudjare, Sofako Egloh, Ayoko Agbodaze, Ahoéfa Vovor and Nadiedjoa Kokou Douti

Article Type: Original Article | Publication Updated: January 07, 2026

Introduction: Sickle cell disease is a monogenic disease due to the substitution of a glutamic acid by a valine at position 6 in β-globin leading to the production of abnormal S hemoglobin. The objective was to determine the hemoglobin profile of newborns at Kpalimé hospital. Methods: This was a prospective cross-sectional study conducted from 1 July to 30 September 2024 at the maternity ward of the Kpalimé Prefectural Hospital Centre, focusing on newborns and their parents....

 Open Access DOI:10.23937/2469-5769/1510140

Ecoepidemiology of Child-Adolescent Cancer Mortality in Argentina

Laura De Gracia, Florencia Molinatti, Sergio Montico and Alejandro Oliva

Article Type: Original Article | Publication Updated: January 05, 2026

The relationship between arsenic and agrochemicals exposure with cancer is a controversial issue, which depends on the world’s populations and regions, as well as on the periods under analysis. This study aims at analyzing the possible association between child-adolescent cancer mortality and the environmental conditions of one of the most agriculturally developed regions of Argentina that accounts for a high percentage of the population exposed to elevated levels of arsenic....

 Open Access DOI:10.23937/2572-4037.1510076

Feeling Good Vs. Living Well: A Deeper Look at Human Flourishing

Aman Aher, MBBS and Manisha Jaywant Aher, MBBS, DGO, MA

Article Type: Original Article | Publication Updated: January 04, 2026

Happiness and well-being are frequently conflated in both academic and public discourse, yet they constitute distinct psychological constructs with unique theoretical and practical implications. While happiness is typically operationalized as transient affective states or global life satisfaction [1], well-being encompasses more enduring aspects of psychological functioning, including purpose, personal growth, and social connectedness....

 Open Access DOI:10.23937/2572-4037.1510075

Cognitive Science: The Dependence of Sensory Perception

Theofilidis Antonis and Katsarou Dimitra

Article Type: Research Article | Publication Updated: January 02, 2026

Decades before the Fodor-Churchland controversy, Gibson (1947) had pointed out that perception is not a passive recipient of external processes with an instantaneous onset but an active process of exploration of the organism that seeks and obtains information from the environment in a flow of continuous interaction (Sensation, Perception, Experience, Representation). How we go from one step to the next is not clear. Eysenck [1] believes that perception is influenced mainly by information that co...

 Open Access DOI:10.23937/2378-3656/1410472

When Stones Speak: E. Coli Sepsis Leading to the Diagnosis of Hyperparathyroidism

Mandeep Kaur

Article Type: Clinical Case | Publication Updated: December 30, 2025

We describe a 64-year-old woman with hypertension and gastroesophageal reflux disease who presented with fever, chills, and abdominal discomfort. Evaluation revealed an obstructive right-sided ureteral stone with sepsis due to Escherichia coli bacteremia. Urological intervention with cystoscopy and ureteral stent placement was performed. The case was further complicated by hypercalcemia secondary to primary hyperparathyroidism, likely contributing to recurrent nephrolithiasis, and sepsis-associa...

 Open Access DOI:10.23937/2378-3656/1410471

Incidental Finding of Primary Ovarian Malignancy at Cesarean Section: A Case Report

Emily Ensley, Danielle Pischullaa, Ashley Barra, Scarlett Bloodworth, Katelyn Jo Light and Hector Chapa

Article Type: Case Report | Publication Updated: December 30, 2025

The prognosis of cancer is highly dependent on its stage at diagnosis, with early diagnosis strongly correlating with better treatment outcomes. The incidence of discovering cancer during pregnancy has steadily increased over the years, with 1/2000 cases reported in the 1960s to 1/1000 cases currently reported.1 However, these diagnoses are primarily driven by patients experiencing symptoms that prompt their healthcare team to investigate the possibility of cancer. Incidental findings of cancer ...

 Open Access DOI:10.23937/2378-3656/1410470

Platypnea-Orthodeoxia Syndrome: A Clinical Presentation Associated with Patent Foramen Ovale

Bereket T. Lodebo, Sunny Patel, Noah Williams and David Watson

Article Type: Case Report | Publication Updated: December 30, 2025

We report a 90-year-old male with persistent hypoxemia, suggestive of POS. Transesophageal echocardiography revealed a large PFO with right-to-left shunting. The PFO was closed percutaneously using the GORE CARDIOFORM septal occluder. Remarkably, the patient demonstrated significant improvement in oxygenation after the procedure....

 Open Access DOI:10.23937/2378-3656/1410469

Thalassemia in the 21st Century: Challenges, and Solutions, a Review Article

Suad M. Jatal, Sawsan J. Harfouch and Rim M. Harfouch

Article Type: Case Report | Publication Updated: December 30, 2025

Thalassemia is among the most common inherited hemoglobin disorders worldwide, caused by mutations that impair the production of alpha or beta globin chains, resulting in chronic hemolytic anemia and significant morbidity. Advances in supportive care, such as regular blood transfusions and iron chelation therapy, have dramatically improved survival, yet iron overload, cardiac failure, endocrine dysfunction, and infections remain major complications. This review summarizes the current understandi...

 Open Access DOI:10.23937/2378-3656/1410468

Perforated Richter’s Femoral Hernia in a Geriatric Patient: An Uncommon Cause of Intestinal Obstruction. Case Report and Literature Review

Alejandra Carrera Holguin and Cecilia Estefania Estrada Chacon

Article Type: Case Report | Publication Updated: December 30, 2025

Richter's hernia is a rare subtype of femoral hernia in which only the antimesenteric portion of the bowel wall becomes incarcerated, potentially leading to ischemia and perforation without complete luminal obstruction. We present the case of a 90-year-old woman with hypertension who developed abdominal distension, pain, and intolerance to food....

 Open Access DOI:10.23937/2469-5807/1510165

Comparative Performance Evaluation of FDA-Cleared Whole Slide Imaging Scanners: A Scientific Review

Bradford Kuhlman, Takenori Fukumoto, and Ram Bedi

Article Type: Review Article | Publication Updated: November 22, 2025

Digital pathology systems are revolutionizing histopathological diagnostics by enabling automated analytics from high-resolution digital images of the entire tissue specimen placed on the surface of a glass slide. Novel applications such as remote diagnosis or workload balancing in large hospitals are becoming a reality. Although there are many manufacturers who market whole slide imaging (WSI) scanners, only six devices to date have undergone the rigorous U.S. Food and Drug Administration (FDA)...