Open Access DOI:10.23937/2643-3885/1710063

Primary Rosai-Dorfman Disease in 39-Year-Old Female with Osseous Tibial Lesion Manifestion: A Case Report and Literature Review

Jasmin Mansoori, DPM, Ivana O Akinyeye, Michael A Sobolevsky, DPM and Robert H Quinn, MD

Article Type: Case Report | First Published: December 02, 2021

Rosai-Dorfman disease (RDD) otherwise known as sinus histiocytosis with massive lymphadenopathy (SHML), is a very rare and benign disorder of unknown etiology with < 10% bone involvement. The following is a case seen at our hospital of a patient presenting with several months’ onset unspecified non traumatic ankle pain. There was no physical mass or lymphadenopathy appreciated on exam. Plain radiographs and MRI demonstrated an osteolytic lesion at the medial malleolus. Biopsy revealed the dia...

 Open Access DOI:10.23937/2643-3885/1710062

Bilateral Peroneal Tendon Subluxation of an Adolescent Female with MRI Correlations

Daniel R Barr, MSc, Nicholas L Newcomb, BS and McCall G McDaniel, MD

Article Type: Case Report | First Published: December 01, 2021

Peroneal subluxation is relatively rare and commonly misdiagnosed as an ankle sprain. Due to its rarity, the incidence of subluxation is unknown, but it has been seen most often in young adults. Peroneal subluxation in pediatric patients is very rare and bilateral subluxation is even rarer. We present a pediatric case of bilateral peroneal tendon subluxation caused by minimal trauma with no known risk factors. Based on a literature review, this is the first reported case of acquired bilateral pe...

 Open Access DOI:10.23937/2378-2951/1410243

Draw your Heart Disease: A Graphic Assessment of the Knowledge of Congenital Heart Disease of Patients and their Parents

Paula Mariño García, Ángeles Fuertes Moure, Isaac Martínez Bendayán, Vanesa Balboa Barreiro and Fernando Rueda Núñez

Article Type: Descriptive Cross-Sectional Study | First Published: December 03, 2021

Patients with congenital heart disease are a chronically ill population. Knowledge of the disease is a key factor in promoting an appropriate attitude towards health. The aim of this study is to evaluate the understanding of heart involvement by describing the heart disease and drawing a picture of the heart by patients and parents. Descriptive cross-sectional study over an 8-month period in a tertiary pediatric cardiology center, involving 201 parents and 123 patients, of whom 74 were between 8...

 Open Access DOI:10.23937/2469-5696/1410070

Echelons of Some Haemoparasites among Blood Donors in Port Harcourt, Rivers State, Nigeria

Evelyn Mgbeoma Eze, Serekara Gideon Christian, Ransom Baribefii Jacob, Barinaaziga Sunday Mbeera, Beatrice Wobiarueri Moore-Igwe and Angela Tornubari Mbari

Article Type: Original Article | First Published: December 04, 2021

Although the therapeutic application of whole blood and blood components can be life-saving, inadequate screening of these products could pose life-threatening problems to the recipient. The aim of this study was to determine the echelons of some haemoparasites (malaria parasite, microfilaria and babesia species) among blood donors in Port Harcourt, Rivers State, Nigeria as well as quantifying their densities. A total of one hundred (100) prospective blood donors from the participating blood ban...

 Open Access DOI:10.23937/2377-4630/1410128

Consensus Reached on How to Recognise and Manage Sepsis and Septic Shock by Intensivists in Northeast Nigeria Held at the University of Maiduguri Teaching Hospital, Borno State Nigeria

Adamu A Sadiq, Ballah Abubakar, Shehu U Panda, Hassan MA, Buma GB, Dakum Longji, Jimoh L Mufutau and Alfa Ndakotsu

Article Type: Case Report | First Published: December 04, 2021

Worldwide, sepsis is a serious health threat and is among the leading cause of death in patients admitted into Intensive Care Units in hospitals across Nigeria and northeastern Nigeria, in particular. Patients of all sexes and ages are affected. However, the vulnerable groups such as extremes of ages (neonates and elderly), pregnant women, the immune-compromised, and those with underlying chronic medical conditions are more at risk. As a low income country, sepsis is a major burden to our health...

 Open Access DOI:10.23937/2377-4630/1410127

Rapid Progression of Neonatal Respiratory Distress from Laryngeal Cleft Type I: A Case Report

Yumi Doi, MD, PhD and Eiji Nishijima, MD

Article Type: Case Report | First Published: December 02, 2021

A one-month-old boy showed cyanosis and severe retraction on crying. He underwent diagnostic rigid bronchoscopy under general anesthesia, maintaining spontaneous ventilation. Rigid bronchoscopy revealed laryngeal cleft type I and excessive mucosa in the interarytenoid space that protruded into the subglottic area, very unusual findings in laryngeal cleft. His clinical condition quickly deteriorated and tracheotomy was performed to prevent complete airway obstruction in the few days until surgica...

 Open Access DOI:10.23937/2690-3164/1710011

Mitochondrial Dysfunction and Insulin Resistance: Topic of High Interest in Research

Ivan Lozada Martinez, Daniela Torres Llinás, Jaine Anaya Rivera, Jennifer Jiménez Valverde and Milena Castro Berrio

Article Type: Commentary | First Published: December 06, 2021

Insulin resistance is a condition derived from the disorder in the use of substrates for metabolic activities. It can be caused by chronic hyperinsulinemia, inflammation, and long-term use of corticosteroids. In vivo and in vitro models have revealed that this process is secondary to the excessive production of mitochondrial oxidants, a product of mitochondrial dysfunction, even in cases where mitochondrial respiration is conserved. Insulin increases the number of type 4 glucose transporters (GL...

 Open Access DOI:10.23937/2643-4512/1710071

Susceptibility Profile among Isolates of S. marcescens Obtained from Clinical and Non-Clinical Sources, Ile-Ife, Osun State, Nigeria

Awoderu BO and Omololu-Aso J

Article Type: Research Article | First Published: December 08, 2021

This study investigated the antibiogram profile of Serratia marcescens among hospitalized individuals, hospital environments and halls of residence of Obafemi Awolowo University in Ile Ife, Osun state with a view to provide key information on resistance factors that are of therapeutic importance among the understudied pathogen. Two hundred and twenty samples from clinical and nonclinical sources were collected with ethical clearance approval (ERC/2018/09/02) from the hospital advisory committee....

 Open Access DOI:10.23937/2643-4512/1710070

Covid-19 Pandemic: Perspectives of Preclinical Medical Students and Effects on Their Lifestyles

Nevin Yılmaz, Ayşe Mısırlı, Dilara Kısaçam, Ecem Ersözlüoğlu, Görkem Becer and Sıdıka Nur Kardaş

Article Type: Original Article | First Published: December 06, 2021

COVID-19 has appeared in Wuhan in December 2019. It has become an epidemic, leading to the transition to online education in medical schools, and students have been affected in some way by the pandemic. This study aimed to investigate perspectives of Eastern Mediterranean University (EMU) preclinical medical students on COVID-19 and its effects on their lives. The novel coronavirus has appeared at the end of December of 2019, in Wuhan city of China. It spread rapidly and affected other regions o...

 Open Access DOI:10.23937/2378-3656/1410374

Acute Wound with Varicose Vein in Rural Setting: The Challenge and Importance of Comorbidity Management

Agustini Song, MD, Kevin Leonard Suryadinata, MD and Nabila Viera Yovita, MD

Article Type: Case Report | First Published: November 30, 2021

Acute wound healing with comorbidities, such as a varicose vein, may be impaired and result in prolonged healing and unsightly scar if comorbidity identification and management are not done properly. We aimed to present the alternative comorbidity diagnosis and treatment for better outcome in rural setting. A 59-year-old woman was admitted to the ED with an open wound on the dorsolateral side of her left foot with comorbidity of uncontrolled hypertension and varicose vein. After wound closure wi...