Open Access DOI:10.23937/2643-4474/1710096
Treatment of Familial Hypercholesterolemia with Intracranial Xanthoma: Case Report
XiaoBo Kou, MS, LunXin Liu, MD and LiangXue Zhou, MD
Article Type: Case Report | First Published: February 05, 2022
Intracranial xanthoma is a rare benign intracranial tumor. It often occurs in patients with hyperlipidemia. Intracranial xanthomas grow slowly, and clinical symptoms only appear when the mass compresses the surrounding tissues, so early diagnosis of the disease is difficult. A 25-year-old female complained of right-sided facial paralysis and hearing loss for 4 years, and an intracranial mass was found for 1 week. The patient had a history of FH and excision of the left elbow mass; positive sign:...
Open Access DOI:10.23937/2572-4193.1510113
Smallest Missed Foreign Body in Neck: A Case Report
Veerasigamani Narendrakumar
Article Type: Case Report | First Published: February 05, 2022
Foreign body impaction in the head and neck region may result from either a traumatic or an iatrogenic injury. Penetrating neck injuries with impacted foreign bodies are of special concern as the neck contains many vital structures. Hence, early detection and removal of the foreign bodies is imperative to prevent life threatening complications. Here, we report a 50-year-old male patient with a very small sharp metallic foreign body impacted in the soft tissue of the neck. The patient underwent w...
Open Access DOI:10.23937/2474-3658/1510249
What are the Missed Opportunities in Prevention Interventions for HBV, HCV and HIV among Key Populations along the Northern Transport Corridor in Kenya?
Joseph Mwangi, Timothy Muasya, Eva Mwai, Joyceline Kinyua, Dama Olungae, Rency Lel, Lihana Raphael, Judy Chege, Alex Maiyo, Nancy Lagat, Lucy Kanyara, Oira Robert, Sheila Kageha, Vincent Okoth, Elijah Songok and Khamadi Samoel
Article Type: Original Article | First Published: February 05, 2022
Viral infections including HIV, HBV and HCV are important public health concern. Due to shared risk factors, mode of transmission and chronicity, prevention of these infections is likely to reduce morbidity and mortality associated with the viruses. While a number of prevention interventions are available and have been rolled out globally, a number of factors account for continued transmission of these three viral infections. Estimates indicate that close to 600 million people are infected with ...
Open Access DOI:10.23937/2474-3658/1510248
Black Fungus Development in SARS-COVID-19 Patients
Danilo Coco and Silvana Leanza
Article Type: Review Article | First Published: February 04, 2022
Mucormycosis refers to a fungal infection resulting from fungus that belong to the order Mucorales and was first described in 1885 by Paltauf. Being the third most prevalent opportunistic fungal infection after candidiasis and aspergillosis, it causes significant endothelial damage by invading the vascular wall. Multiorgan failure and sepsis develop owing to its spread toward the brain. It usually has poor prognosis and it is impacted by the time it takes to diagnose and most significantly the p...
Open Access DOI:10.23937/2474-3658/1510247
Post-COVID 19 and Neuropathic Pain
Sinan ELIAÇIK, Funda UYSAL TAN and Aysel KOCAGÜL ÇELIKBAŞ
Article Type: Original Article | First Published: February 03, 2022
In this study, we compared neuropathic pain in post-COVID patients with a healthy control group who did not have COVID-19. We aimed to draw attention to neuropathic pain in the post-COVID period. A total of 169 individuals participated in the study. 89 cases constituted the post- COVID group and 80 cases constituted the control group. In our case series, patients were in the post-COVID period and the control groups were assessed with the Douleur Neuropathique 4 (DN4) and Self-Leeds Assessment of...
Open Access DOI:10.23937/2474-3658/1510246
Cholera Scourge in Nigeria: Promoting Environmental Sanitation Practice to Achieving Good Health for All
Olajide Mariam Olaitan, Tajudeen Kaosarat Oluwatobi, Popoola Victor Oluwaseun, Onyeanusi Sandra Adaobi, Makinde Abubakar Abiodun, Oladapo Rasaq Kayode, Onyinyechi Patience Obidiro, Oyetola Afeez Babatunde, Adekunle Olajide and Akinrinde Barakat
Article Type: Commentary | First Published: January 31, 2022
The present surge in cholera cases in Nigeria especially among the vulnerable is quite worrisome and alarming. Several factors account for the prevalence of cholera in Nigeria, which includes but is not limited to poor living conditions, lack of potable water, sanitation, and hygiene (WASH) services. Interestingly, Environmental sanitation has been identified as integral in achieving a healthy environment. It involved controlling all the factors in man’s physical environment which may cause ha...
Open Access DOI:10.23937/2474-3658/1510245
Persistence Viral Shedding of SARS-CoV-2 in Feces and Potential Transmission
Mauro MV, Greco S, Vitiritti M, Elia N, Mastroianni A and Greco F
Article Type: Original Article | First Published: January 30, 2022
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths worldwide. Despite the recent availability of vaccines, with the ongoing and rapid spread of SARS-CoV-2 worldwide, laboratory testing remains the cornerstone of public health containment and mitigation strategies. Also, although not used routinely in many laboratories, detecting SARS-CoV-2 RNA from stool is possible in the pres...
Open Access DOI:10.23937/2474-3658/1510244
COVID-19: SARS-CoV-2 Seroprevalence in a Blood Bank in Southern Brazil
Maria Augusta Bogo, Djulia Adriani Frainer, Luisa Pisacane, Paulo Henrique Condeixa de França and Luiz Henrique Melo
Article Type: Original Article | First Published: January 14, 2022
To determine the seroprevalence of antibodies to SARS-CoV-2 in asymptomatic individuals in a blood bank in southern Brazil. 1015 serological analyses were performed between November 2020 and March 2021 in Joinville, Brazil, to detect IgG and IgM antibodies against SARSCoV- 2, and the results were correlated with the participants' age, gender, city and neighborhood. The seroprevalence of total antibodies was 40.4%, with reagent IgM detected in 9.4% of cases, IgG in 18.5% and both immunoglobulins ...
Open Access DOI:10.23937/2643-461X/1710056
Analysis of IgG Responses to P. falciparum Antigens MSP1, MSP4-20 and MSP4-40 during Severe Malaria in Dakar, Senegal
Bruce Shinga Wembulua, Kalilou Diallo, Folly Mawulolo Gaba, Babacar Mbengue and Louise Fortes
Article Type: Original Article | First Published: February 07, 2022
Antibodies to merozoite surface antigens (MSPs), the primary targets of malaria vaccine research, are associated with low malaria morbidity. However, few studies have looked at the implications of their variations on the evolution of clinical-biological forms of severe malaria. This cross-sectional, prospective, and analytical study evaluates by ELISA the IgG responses directed against the antigens MSP1, MSP4-20 and MSP4-40 of P. falciparum during severe malaria in patients hospitalized in the i...