Open Access DOI:10.23937/2469-567X/1510080
Prevalence and Human Papillomavirus Genotypes Distribution among HIV-Positive and -Negative Young Women Aged 20 to 37-Years-Old with Cervical Cancer in Abidjan, Côte d’Ivoire
Nanga Yessé Zinzendorf, Cablan Mian Asher, Zaba Flore Sandrine, Apete Tahou Sandrine, Brou Kouakou Pierre, Ouassa Timotée, Dotia Agathe, Lathro Serge Joseph and Agbessi-Kouassi Bra Thérèse
Article Type: Research Article | First Published: March 12, 2022
Human papilloma virus (HPV) infection is the major etiologic agent of cervical cancer. Both human papillomavirus (HPV) and human immunodeficiency virus (HIV) are classified as carcinogens. We describe the prevalence and distribution of HPV genotypes among HIVpositive and -negative women aged 20-37 years-old in Côte d’Ivoire. Women were recruited among those who come to the gynaecology department of the Military Hospital, Abidjan with a positive acetic acid test. HIV testing was performed on t...
Open Access DOI:10.23937/2469-5769/1510090
A Text Message Intervention for Weight Management in Childhood Obesity at the Pediatric Office
Ala Elayyan, MD, MPH, FAAP, CNSC, Dipl. of ABOM
Article Type: Research Article | First Published: March 09, 2022
Childhood overweight and obesity is a major public health problem affecting one-third of children and adolescents in the United States, it has been linked to significant health risks and comorbid conditions in children and adults as it has direct associations with chronic health problems in children and adults not limited to diabetes, dyslipidemia, heart disease, non-alcoholic fatty liver disease, and many others. Childhood obesity is usually diagnosed and managed at the primary care office but ...
Open Access DOI:10.23937/2469-5769/1510089
Effectiveness of Polyethylene Glycol 3350 versus Lactulose in Management of Functional Constipation in Children
Hanin Ahmed Mansour, MD, Ali Ibrahim and Ali Mohammad
Article Type: Research Article | First Published: March 09, 2022
Constipation is one of the common problems in childhood. Recently, Polyethylene Glycol (PEG 3350) has been suggested as a good alternative laxative to Lactulose as a treatment option in pediatric constipation. The current study aimed to compare the efficacy of two laxatives (PEG 3350 and Lactulose) in the management of functional constipation and evaluate the side effects. In an open-label clinical trial, 1-13 year-old children with functional constipation according to ROME IV criteria and the p...
Open Access DOI:10.23937/2377-3634/1410154
Association between Smoking and the Switching to Insulin Therapy in Type 2 Diabetes Patients
Zuhal Aydan SAGLAM, Tayyibe SALER and Şennur KÖSE
Article Type: Original Research | First Published: March 12, 2022
Since no studies have been published on how active smoking affects switching to insulin therapy, we aimed to investigate the role of smoking on switching to insulin therapy in type 2 diabetes mellitus patients. A total of 532 type 2 diabetes mellitus patients, who started insulin treatment due to the inability to achieve glycemic control with maximum oral anti-diabetic treatment, were included in the study. The patients were divided into three groups according to their smoking status at the beg...
Open Access DOI:10.23937/2474-3674/1510141
Cardiovascular Collapse, Progressive Lactic Acidosis, Pulmonary Hypertension and Polyuria: Think Thiamine Deficiency!
Gul Sher, MBBS, Mona Nourani, DO, Kristen Beebe, PA-C, Peggy Fullenkamp Oomens, MS, RDN, CNSC, Megan Land, MD and Alexander Ngwube, MD
Article Type: Original Article | First Published: March 13, 2022
Shock is a pathological condition characterized by imbalance between oxygen demand and supply. Irrespective of the cause, shock leads to a state of energy failure due to a decrease in adenosine triphosphate (ATP) production, creation of lactic acidosis, and as a consequence, multiple organ dysfunction. Lactic acidosis is an ominous finding in critically ill patients. The severity and increased duration of lactic acidosis are associated with increased mortality. Lactic acidosis can result from hy...
Open Access DOI:10.23937/2378-3656/1410385
Spontaneous Rupture of Renal Pelvis Secondary to Extrinsic Compression of Sigmoid Volvulus
Kasturi Rangan Sarathy, Arun Jain and Abdus Samee
Article Type: Case Report | First Published: February 28, 2022
Spontaneous rupture of the renal pelvis is one of the rare complications and is commonly known to occur secondary to obstructed distal ureteric calculus. Malignant ureteric obstruction and bladder outlet obstruction are few other causes that could like to rupture of renal pelvis secondary to the back pressure changes. Pregnancy is one of the non-renal extraluminal causes of the spontaneous renal fornix rupture. However, blowout of renal pelvis secondary to an obstructing bowel has not been repor...
Open Access DOI:10.23937/2378-3656/1410384
Blue Laser Imaging and Magnification Endoscopy as a Tool for the Detection of Helicobacter pylori Infected Mucosa
Ulises Leal-Quiroga, MD, Abigail Sara Kane, MD, Eduardo Mendoza-Fuerte, MD, Omar David Borjas-Almaguer, MD, Eugenia Leal, MS and Rafael Castañeda-Sepúlveda, MD
Article Type: Original Article | First Published: February 28, 2022
There are multiple diagnostic methods for the detection of H. pylori; however, because most are not cost-effective and have low sensibility and specificity, gastric biopsy remains the gold standard for diagnosis. H. pylori’s patchy distribution in the gastric mucosa requires multiple biopsy samples to accurately diagnose infection. This study’s objective is to identify the diagnostic value of using BLI-Bright with magnification endoscopy as a tool for guided biopsy sampling in patients with ...
Open Access DOI:10.23937/2378-3656/1410383
Patients with Pelvic Inflammatory Disease vs. Tuboovarian Abscess: Comparison of Follow-Up and Treatment Processes
Busra Kanyildiz, MD
Article Type: Original Research | First Published: February 24, 2022
Pelvic inflammatory disease (PID) is an infection of the upper vaginal tract in women that can be subclinical or severe, affecting any or all of the uterus, fallopian tubes, and ovaries. Tuboovarian abscess (TOA) is a common consequence of PID. The purpose of this study is to compare the demographic features, symptoms, clinical findings, and treatment techniques of patients hospitalized with the diagnosis of PID and TOA, to assess their response to treatment protocols and therapy, and to evaluat...
Open Access DOI:10.23937/2474-3682/1510198
Tuberculous Pericardial Effusion in an Immunocompromised Patient- A Lethal Combination
Nishant Patel, Abhishek Singh, Rakesh kumar and Richa Aggarwal
Article Type: Clinical Image | First Published: March 09, 2022
A 23-year-old male was diagnosed with acute myelocytic leukemia was started on induction chemotherapy but despite treatment, he did not go into remission and developed fever, cough, and respiratory distress. He tested positive for COVID-19. Further investigation revealed the presence of pulmonary tuberculosis and antitubercular treatment was started. Two days later, he developed respiratory distress and 2D echocardiography along with High-resolution computed tomography was done which showed the ...
Open Access DOI:10.23937/2643-4563/1710034
Cell Proliferation, Contact Inhibition, and Apoptosis Profiling in a Benign and Malignant Breast Lesion
Olakayode V Ekundina, Chiamaka C Ejelue, Ondokeyi P Apulu and Ore-oluwa O Ayodele
Article Type: Original Article | First Published: January 29, 2022
Monitoring and diagnosis of benign or premalignant breast lesions as it progresses to a malignant condition is very necessary for its ability to predict or curb the progression of a breast lesion to the malignant condition and Immunohistochemistry has been proven to be a useful tool in achieving this as immunohistochemical markers are corresponding and specific in nature. The primary objective of this case-control study is to study the expression of KI67, E-cadherin, and P53 in normal breast tis...