ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.



  Last Updated: January 16, 2021

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2643-4474/1710049

Orbital Apex Syndrome and Carotid Artery Injury Associated with Transorbital Stab Injury

Dimitri Laurent, MD, Brian Corlis, MD and Gregory JA Murad, MD

Article Type: Case Report | First Published: December 09, 2020

Transorbital penetrating injuries are particularly rare in the adult population. We present a case of TOPI sustained in an assault using a ballpoint pen-with concomitant transmaxillary injury due to a pencil stab wound-and a review of the literature. Transorbital penetrating injuries (TOPI) are particularly rare in the adult population, accounting for 0.096% of all head injuries. In the setting of TOPI, there should be a high index of suspicion for damage to the intracranial vascular and neural ...

 Open Access DOI:10.23937/2469-5726/1510088

CTGF Signaling in Skeletogenesis, Articular Cartilage, and Osteoarthritis Development

Eduardo Branco de Sousa and Diego Pinheiro Aguiar

Article Type: Review Article | First Published: December 21, 2020

CTGF/CCN2 is involved in many cellular events related to proliferation and migration. Its main physiological role is related to the promotion of endochondral ossification, besides regeneration, protection of bone and articular cartilage, and angiogenesis. Skeletogenesis, the process by which bone and articular elements are formed, comprises endochondral and intramembranous ossification. However, the signaling pathways that mediate CTGF/CCN2 expression in chondrocytes have not been fully understo...

 Open Access DOI:10.23937/2572-4193.1510096

Retrograde Air Flow through the Lacrimal Drainage System with Valsalva Maneuver

Swati Malik, B.A., Mohammad Javed Ali, F.R.C.S., Miel Sundararajan, M.D. and Harsha S. Reddy, M.D.

Article Type: Case Report | First Published: December 14, 2020

We present a series of three clinical videos of retrograde air flow through the lacrimal system with Valsalva maneuver that illustrate the hypothesized dysfunctions at various points within the lacrimal valvular system. Under normal physiologic conditions, the lacrimal excretory system has a series of valves that prevent retrograde flow of fluid and air. Therefore, while performing the Valsalva maneuver, increased intranasal pressure is not transmitted to the nasolacrimal system; however, trauma...

 Open Access DOI:10.23937/2572-3243.1510089

Musculoskeletal Pain and Postural Abnormalities among Smartphone-Using Digital Natives

Adesola C Odole, Dorcas A Olutoge, Oluwagbohunmi Awosoga, Chidozie E Mbada, Clara Fatoye, Olufemi O Oyewole, Ruth I Oladele, Francis A Fatoye and Aderonke O Akinpelu

Article Type: Original Article | First Published: December 16, 2020

The younger generations are labeled “digital native” among whom smartphone penetration and adoption is high. However, the health consequences of intense utilization of smartphones as a contributor to the increasing prevalence of musculoskeletal disorders in young adults are less explored. This study investigated patterns of musculoskeletal pain, postural abnormalities, and smartphone usage among undergraduate university students. Four hundred (200 males and 200 females) two-staged sampled un...

 Open Access DOI:10.23937/2474-3658/1510181

Personal Protection Equipment Utilization and Hand Hygiene Practice during COVID-19 Pandemic: A Narrative Review

Azmeraw Bekele and Yimenu Yitayih

Article Type: Review Article | First Published: December 16, 2020

Personal protective equipment and instant hand hygiene found the most effective preventive measures during coronavirus disease-19 and their utilization should depend upon contact-droplet exposure. The aim of the review was to evaluate when, where, and how the personal protective equipment utilized and hand hygiene practiced during SARS-CoV-2 infection. The following databases were searched using keywords and related browsing terms: PubMed Central, Ovid Medline via PubMed, Cochrane database, WHO ...

 Open Access DOI:10.23937/2474-3658/1510180

Hybrid Autopsy Virology Laboratory Experimental Platform

Izak B Dimenstein, MD, PhD, HT (ASCP)

Article Type: Commentary | First Published: December 11, 2020

The SARS-CoV-2 aerosols’ transmission route is not still settled. Along with epidemiology data, there is an urgent necessity for reliable reproducible experimental methods for virus aerosolization studies. The autopsy table can form part of a hybrid autopsy virology laboratory as an investigative platform equipped with the necessary instruments for SARS-CoV-2 aerosolization studies. Wide open mucosa surfaces COVID-19 deceased can be a field for studying under experimental manipulations of air ...

 Open Access DOI:10.23937/2474-3690/1510053

The Cardio-Vascular and Metabolic Treatments in Canada: Assessment of Real-Life Therapeutic Value Registry (CV-CARE): Registry Description and Baseline Patient Demographics

Goldenberg Ronald, Cheng Willoon, Bell Alan, Burrows Melonie Blavignac Jessica, Paron Emilia, Nadège Fils-Aimé and Barakat Maxime

Article Type: Research Article | First Published: December 12, 2020

Bausch Health Canada cardiovascular and metabolic treatment portfolio has been shown to be safe and effective in clinical trials. However, in clinical trials, data is collected in selective populations under ideal conditions, making inference to the real-world problematic. Well executed patient registries are required to provide evidence of the benefits of therapeutic agents under routine, real world conditions. The ‘Cardio-Vascular and metabolic treatments in Canada: Assessment of REal-life t...

 Open Access DOI:10.23937/2378-3648/1410052

Y Chromosome Sequences in Turner Syndrome: Multiplex PCR, a New Method for Diagnosis

Lene Garcia Barbosa Maria Anunciação Souza, Adriana Aparecida Siviero-Miachon, Magnus Régius Dias-da-Silva and Angela Maria Spinola-Castro

Article Type: Brief Report | First Published: December 02, 2020

Turner’s syndrome is characterized by the partial or complete absence of one of the sex chromosomes in women in association with one or more clinical exposures. Molecular techniques such as polymerase chain reaction (PCR) are useful when it comes to complementing the genetic approach, as they present greater sensitivity in recognizing mosaicism. Considering the high percentage of mosaicism and the possible clinical impact of the presence of Y chromosome in these patients, we proposed in this s...

 Open Access DOI:10.23937/2572-3286.1510060

The Effects of the Symptoms Experienced by Patients Undergoing Hemodialysis Treatment on their Comfort Levels

Rukiye Demir Dikmen and Hakime Aslan, PhD

Article Type: Original Article | First Published: December 17, 2020

This is cross-sectional study. The population of consisted of patients aged over 18 who received treatment at three hemodialysis centers in Elazig province and two in Bingol province. Sampling method was not used as it was aimed to reach the whole population. The research was carried out with 363 patients (84% of the population) meeting the research criteria. The data was collected between June-October 2019. Personal Information Form, Hemodialysis Comfort Scale (HDCS), and Dialysis Symptom Index...

 Open Access DOI:10.23937/2469-567X/1510072

The Transformation of Burnet’s Immune Surveillance Cells into Natural Killer Cells and its Circumstances

Joseph Geza Sinkovics and Joseph Csaba Horvath

Article Type: Case Report | First Published: December 17, 2020

In 1969 it was very difficult to explain the sudden unexpected appearance of some finely granulated large lymphoid cells that had been hidden in the human blood for over a full century, as they suddenly revealed themselves in our laboratory at M.D. Anderson Hospital, Houston TX. At first, the hematopathologists considered these cells to be of monocytoid (M) derivation; by accidental misprint, instead of monocytoid noted as “macrophagic” in the legends. These new cells appeared clearly distin...

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