Magnetic Resonance Imaging of Symptomatic Swimmer’s Shoulder
Jake T Stahnke, DO, Mari Schenk, MD and Kipling P Sharpe, MD
Article Type: Original Research | First Published: November 16, 2020
Eleven detailed magnetic resonance imaging scans of symptomatic shoulders of swimmers who had arthroscopically demonstrated labral dysplasia were obtained between 2011 and 2014. One experienced musculoskeletal radiologist and one orthopedic surgeon interpreted each scan, specifically focusing on the anteroinferior labrum (from 3 to 6 o’clock). Nine of the eleven images (axial cuts) showed a more rounded/blunted appearance with undefined features at the anterior inferior labrum. Nine of nine im...
Left Sided Inferior Vena Cava in a Patient Diagnosed with Renal Cell Carcinoma
Charalampos Fragkoulis, Ioannis Glykas, Dimitrios Moschotzopoulos, Aggeliki Leventi, Georgios Papadopoulos, Georgios Stathouros and Konstantinos Ntoumas
Article Type: Case Report | First Published: November 13, 2020
Inferior vena cava (IVC) is a major abdominal vein responsible for the transportation of deoxygenated blood from the lower extremities and the abdomen through diaphragm to the superior vena cava and eventually to the right atrium. IVC is located to the right of the midline and is an important anatomic structure in cases of operations involving the right kidney. In this paper we present a rare case of left sided IVC in a patient diagnosed with renal cell cancer who underwent open left partial nep...
A Novel Case of Maffucci Syndrome and a Likely High-Grade Lymphoma
Fleming S, Player P, Ladani S, Miall F, Goldney J and Levy MJ
Article Type: Case Report | First Published: November 16, 2020
A 54-year-old male with a history of Maffucci syndrome and Marginal Zone Lymphoma, presented with a 4-week history of headache, right-sidedptosis and diplopia. Whole-body imaging revealed a mass in the pituitary fossa that was likely lymphomatous. Despite diagnostic uncertainty, the mass was treated as transformation of Marginal Zone Lymphoma to a high-grade lymphoma. This report analyses how and why the multi-disciplinary team treated the patient without a biopsy. The case highlights a possible...
Distal Arthrogryposis Type Six and Systemic Lupus Erythematosus, in a Girl: First Pediatric Case
Houda Nassih, R El Qadiry, A Bourrahouat, and I Ait Sab
Article Type: Case Report | First Published: November 12, 2020
Arthrogryposis type six is one of the distal arthrogryposes. It associates arthrogryposis of the hands and sensorineural deafness. Male-to-male transmission was observed. No gene has been identified to date. We report a unique case of a girl presenting with congenital arthrogryposis-like hand anomaly, sensorineural deafness, and acute onset of systemic lupus erythematosus (SLE). Arthrogryposis-like hand and deafness syndrome or distal arthrogryposis type 6 (DA6) is characterized by an arthrogryp...
Nursing Intervention on Knowledge and Skills of Self-Management of Diabetes among Patients Attending Medical Out-Patient Clinic in Two Tertiary Hospitals in Ondo State
Ajibade Olapeju Oke, RN, RM, BNSc, PGDE and Salawu Rasidi Akinade, BSc (Nursing), RN, RM, PHD, FPNP Adv.Mgt., FWACN
Article Type: Clinical Study | First Published: November 25, 2020
Diabetes mellitus is one of the global health burdens associated with adequate management. Self-management is a pivot of diabetes management. It has been estimated that more than one-quarter of the admissions in Nigeria hospital is as a result of diabetes complication. The study assessed nursing intervention on knowledge and skill of self-management among diabetic patients attending medical out-patient clinics in two tertiary hospitals, Ondo State, Nigeria. This study adopted a two-group, pretes...
Changes in Mobility during COVID-19 as a Response to Government Imposed Restrictions: A Multiple Regression Analysis for the Top Five Populous U.S States
Eitan Flor, Florence George and BM Golam Kibria
Article Type: Original Article | First Published: November 14, 2020
With the rise of the COVID-19 pandemic, several changes occurred in the lifestyle and habits of human life. These include various voluntary and mandatory governmental restrictions, limiting social interaction by encompassing social distancing, travel limitations, social gatherings, personal mobility, as well as closures and reduced capacities in sectors such as retail, restaurants, and the entertainment industry. The purpose of the restrictions ideally intended to reduce the transmission rate of...
A New Two Parameter Biased Estimator for the Unrestricted Linear Regression Model: Theory, Simulation and Application
Issam Dawoud and BM Golam Kibria
Article Type: Original Article | First Published: November 11, 2020
This paper proposes a new biased estimator for estimating the regression parameters for the multiple linear regression models when the regressors are correlated. Theoretical comparisons and simulations results show that, the proposed estimator performs better than other existing estimators under some conditions in the smaller mean squares error sense. A real-life dataset is analyzed to illustrate the findings of the paper. The ordinary least squares (OLS) estimator is the best linear unbiased es...
System Biology: An Emerging Toolkit for Improved Tyrosine Kinase Inhibition Therapy for Myeloproliferative Neoplasms
Alphonsus Ogbonna Ogbuabor, PhD, Peter Uwadiegwu Achukwu, PhD, Silas Anayo Ufelle, PhD and Daniel Chukwuemeka Ogbuabor, PhD
Article Type: Review Article | First Published: November 16, 2020
Concerted efforts have been made by scientists over the last decades in elucidating the molecular mechanisms leading to myeloproliferative neoplasms. The identification of oncogenic mutations in signal transduction pathways revealed the role of specific pathways in inducing excessive proliferation of myeloid lineages. The subsequent development of mouse models carrying mutations found in patients proved that the aberrant activation of these specific pathways plays a crucial role in the pathology...
Erythrocyte Alloimmunization in Children with Sickle Cell Disease
Daniela de Oliveira Werneck Rodrigues, Lysla Cardoso Sudário, Olivia Franco dos Santos and Luiz Claudio Ribeiro
Article Type: Original Article | First Published: November 16, 2020
Alloimmunization is an immune response against red blood cell (RBC) antigens due to sensitization during RBC transfusion. RBC alloimmunization is more common in sickle cell disease (SCD) with prevalence between 18 and 47%. Retrospective chart review of a cohort of 120 children treated at Fundação Hemominas born between 1998 and 2007 and diagnosed with SCD through neonatal screening. The statistical analysis was made with the usage of Mann-Whitney’s U test, Student’s T-test and Chi-Square t...
Trans-Thoracic Echocardiography during VA-ECMO: May the Supra-Sternal Notch View Detect a Too-Proximally Watershed Area?
Enrico Giustiniano, MD and Maurizio Cecconi, MD, FRCA, FFICM, MD(Res)
Article Type: Case Report | First Published: November 19, 2020
Veno-Arterial Extra-Corporeal Membrane Oxygenation (VA-ECMO) in adults has grown over the last decades as a life-saving procedure. Trans-thoracic (TTE) and trans-esophageal (TEE) echocardiography are recommended tool to manage such cases. A 35-years-old female patient suffering from myocarditis after bone marrow transplant for lymphoblastic leukemia underwent V-A ECMO due to a severe Left Ventricle disfunction which developed abruptly. Given the rapid clinical worsening we opted for the extracor...