The Effects of Vitamin E on Non-proliferative Diabetic Retinopathy in Type 2 Diabetes Mellitus
En Yng Ng, Yilynn Chiew, Sonia Chew Wen Phang, Yeek Tat Ng, Gerald Chen Jie Tan, Uma D Palanisamy, Badariah Ahmad and Khalid Abdul Kadir
Article Type: Research Article | First Published: May 23, 2021
Vitamin E, which exhibits anti-oxidant, anti-inflammatory, and anti-thrombogenesis properties, has been shown to improve retinal blood flow in diabetic retinopathy. This study aim to investigate the effects of Vitamin E (Tocovid) on retinal microhaemorrhages and diabetic macular edema (DME) in diabetic retinopathy. A total of 30 participants were randomly allocated to the treatment group or placebo group. The participants in the treatment group (n = 19) received 200 mg Tocovid twice daily while ...
Systematic Review with Meta-analysis: Denosumab in Glucocorticoids Induced Osteoporosis
Mariya M El Akkawi and Ashish Shrestha
Article Type: Meta Analysis | First Published: May 17, 2021
American College of Rheumatology recommends Bisphosphonates as the first choice drug for Glucocorticoids Induced Osteoporosis (GIOP). But denosumab is the promising drug that is recommended as the first choice for post-menopausal osteoporosis. This study was conducted to light up the efficacy and safety of denosumab compared to bisphosphonates in GIOP. Randomized Controlled Trials (RCTs), retrospective, prospective observational Studies, conference abstracts were searched in PubMed, Web of Scien...
Clinical Characteristics of Suspected COVID-19 in Pediatric Patients
Heather Yerdon, BS, Lauren Mutter, MD, Rick Tivis, MPH, Trevor Olsen, PhD and Anna Suessman, DO
Article Type: Case Report | First Published: May 20, 2021
This study reviews patients aged 21 and younger, who presented to the Ochsner Medical Center’s Pediatric Emergency Department during the COVID-19 pandemic. A retrospective analysis was completed comparing demographics, symptomology, and laboratory analysis between COVID positive and negative patients. This study examined pediatric patients presenting to the Pediatric Emergency Department at Ochsner Medical Center between March 11 and May 20, 2020. All children included in the study underwent C...
Evolution of Pediatric Cardiology over the Last 50 Years - Part III
P Syamasundar Rao, MD
Article Type: Review Article | First Published: May 14, 2021
The author has just written a book on the evolution of the specialty of Pediatric Cardiology over the last 50 years. The intent of this review is to present a summary of this book. Because of large amount of this material, the review is separated into four parts. In these first and second parts, transcatheter interventions (balloon angioplasty/valvuloplasty procedures and percutaneous occlusions) were appraised. In this paper, electrocardiography, echocardiography, and cardiac catheterization wi...
An Audit of Paediatric Trauma Management in the Already Established Adult Trauma System
Nadeem Haider, Nijamudeen Kabeer, Kamil Vallabh, Zeyn Mahommed, Marcus Larsson and Fawzi Al Ayoubi
Article Type: Original Article | First Published: May 26, 2021
To study the joint management of paediatric trauma by adult and paediatric surgeons, in an adult trauma system with an embedded paediatric component. We looked at the trauma registry data from January 2019 to June 2020 at Sheikh Khalifa Medical City in Ajman, United Arab Emirates (UAE). The medical records, radiology findings and post discharge outpatients visits records were studied. We had total of 137 paediatric trauma patients (excluding burns). These ages range was between 6 weeks to 16 yea...
The Opinions of Patients Diagnosed Diabetes on Medical Nutrition Therapy: A Phenomenological Study
Leyla Muslu, Melek Ardahan and Ilhan Gunbayi
Article Type: Qualitative Study | First Published: May 20, 2021
For patients with type 2 diabetes mellitus, medical nutrition therapy is one of the most essential components of a healthy life. The aim of this study was to investigate participants’ perceptions of the process of medical nutrition therapy. In this study, a qualitative phenomenological approach was adopted in order to explore in depth the experiences of patients with type 2 diabetes mellitus during the medical nutrition therapy process, which is the most important component of diabetes treatme...
Development and Validation of Qualitative and Quantitative Analytical Method for Identification and Analysis of Amphetamines by Gas Chromatography
Esther Ricci Adari Camargo, Rodrigo Martins P.O. da Trindade, André Augusto R. Felgueiras, Marcella Zaim, Mônica Novaes Ferreira, Juliana Weckx Peña Muñoz, Helenice de Souza Spinosa, Lorena de Paula Pantaleon, Paula A. Faria Waziry and André Rinaldi Fukushima
Article Type: Research Article | First Published: May 22, 2021
During the last few years there has been an increase in consumption of psychostimulants, substances that augment brain activity, in Brazil and around the world. It’s noted that the utilization of these substances involves not only medical need, but also recreational purposes, being the latter identified as indication of substance abuse. Among these stimulants, there are anorexigenics, such as amphetamines and derivatives. Amphetamines are drugs that stimulate the central nervous system, capabl...
Spontaneous Proximal Tibiofibular Joint Ganglion Cyst as a Rare Cause of Acute Foot Drop: A Case Report
Nirguna Thalla, MD, MBA, W Daniel White, MD, J Taylor Mansfield, DO, Jason M Souza, MD and Matthew E Miller, MD
Article Type: Case Report | First Published: May 10, 2021
Fibular neuropathy has several well understood causes. An extraneural ganglion cyst is a poorly understood cause of this clinically important neuromuscular condition. We report a case of a 50-year-old male who developed acute foot drop caused by a compressive ganglion cyst infiltrating the common fibular nerve at the proximal tibiofibular joint. Intraneural ganglion cysts or synovial cysts development affecting the deep fibular nerve has been reported in the literature. To our knowledge, an extr...
Seropositive Prevalence of Antibodies against SARS-CoV-2 in Rural Harnett County, North Carolina
Anita Subramanian, MD, Gualberto B Morco VI OMS IV, Piper Olmsted DO, Qinfeng (Sarah) Liu, PhD and Asif Zia MD, MPH, FACP
Article Type: Epidemiological Survey | First Published: May 03, 2021
Reported infections of SARS-CoV-2 likely underestimate the prevalence of infection in affected communities. Seroprevalence studies allow us to understand how the virus is spreading through this local community and help us to identify people with previous infections known or unknown. This study is an epidemiologic survey to evaluate seroprevalence data in a rural community. Participants were tested between September 2020 to March 2021 using a Biohit SARS-CoV-2 IgM/IgG quick test. The positive fin...
Clinical Efficacy of Ceftaroline Fosamil in Patients with Severe Pneumonia in Intensive Care Unit
María José Pérez-Pedrero Sánchez-Belmonte, Marcelino Sánchez Casado, Roman Hervey Piza Pinilla, Marta Fernández Arevalo and Maria José Sánchez Carretero
Article Type: Clinical Study | First Published: April 24, 2021
Severe community acquired pneumonia is entity with high mortality, it needs effective and early antibiotic therapy, and often the patients need admission in intensive care unit to receive respiratory support. Appearance of new antibiotics have been expanding the therapeutic efficacy, that approves of Ceftaroline fosamil to treat community acquired pneumonia have allowed to use it as a part of usual therapeutic arsenal and it have shown an earlier clinic response and higher cure rate. The goal of...