Treatment of Different Types of Bone Defects with Concentrated Growth Factor: Four Case Reports
Ceren Gokmenoglu, Mustafa Cihan Yavuz, Elif Sadik, Varol Canakci and Cankat Kara
Article Type: Case Series | First Published: June 03, 2016
Various techniques have been attempted in the past to truly regenerate the lost bone structures. Owing to its stimulatory effect on angiogenesis and epithelialization, concentrated growth factor (CGF) is an excellent material for enhancing bone healing. The purpose of these case series is to document the beneficial role of CGF in the healing of different bone defect areas. This report describes four female patients presented with (lateral cyst on tooth 22; periimplantitis on mandibular left firs...
Comparısıon Success Rate of Immedıate Implants at Fresh Extractıon Sockets and Conventıonal Implants
Article Type: Original Article | First Published: May 29, 2016
Immediate implant placement has gained popularity because it can reduce treatment time, number of surgeries and post-extraction bone loss. Following tooth extraction, socket area shows series of physiologic processes, during the recovery time that passes between tooth extraction and the placement of the implant, the majority of the amount of bone resorption and gingival remodeling is confirmed, which is usually the cause of biological, aesthetic and functional damage....
Medial Epicondylitis and Medial Elbow Pain Syndrome: Current Treatment Strategies
Christina Brady and Anil Dutta
Article Type: Review Article | First Published: June 03, 2016
Medial elbow pain is a common complaint in the active population. The most frequent muscular or tendinous condition to cause medial elbow pain is Medial Epicondylitis (ME). The disorder is classically described as Golfer's elbow due its association with elbow pain caused by excessive eccentric force across the common flexor origin encountered during the golf swing. In the working population, the condition is frequently associated with repetitive use and is seen in manual laborers who require for...
Regenerative Therapy in Osteoarthritis of the Knee
Jonathan Theo and Edward Pang
Article Type: Literature Review | First Published: May 21, 2016
Osteoarthritis (OA) is the most common joint disorder in the world. It commonly affects the knee and current treatment options are limited, focusing mainly on symptom relief. It is now known that OA is the result of both mechanical and biological events that disrupt anabolic and catabolic processes in the joint. Recently, research in regenerative therapies has been gaining interest because of its potential to restore normal structure and function following tissue injury. The goal is to use the b...
Sedaghatian-Type Spondylometaphyseal Dysplasia: A Case of Rapid Demise with Evidence of Myocardial Injury
Mehmet Sah Ipek and Alper Akin
Article Type: Case Report | First Published: June 02, 2016
Sedaghatian-type spondylometaphyseal dysplasia (SSMD) is a lethal neonatal form of spondylometaphyseal dysplasias that is reported rarely. The case of a female infant demonstrating a clinical phenotype consistent with a diagnosis of SSMD was presented. She died with acute evidence of myocardial injury. In SSMD, certain organ systems including the central nervous, cardiac, and skeletal systems, are clearly involved. Although the exact cause of the uniform fatality remains unclear, cardiac involve...
A Perspective on the Algorithms Predicting and Evaluating the RNA Secondary Structure
Giulia Fiscon, Giulio Iannello and Paola Paci
Article Type: Review Article | First Published: May 20, 2016
Investigating the RNA structure contributes greatly to understand RNA roles in cellular processes. Indeed, functional RNAs show specific instrumental sub-structures for their interaction with other molecules. The RNA structure prediction will provide fundamental insights into developing hypothesis connecting function to structure, but it is a challenging and unsolved task yet. We aim at discussing the current status of the widespread RNA folding tools and comparing their performances on RNA fami...
Effect of Elasticity on Flow Characteristics Inside Intracranial Aneurysms
Ryuhei Yamaguchi, Gaku Tanaka and Hao Liu
Article Type: Review Article | First Published: May 25, 2016
Many medical and bioengineering researchers have investigated flow behavior inside intracranial aneurysms using computational fluid dynamics. The majority of these studies assume to be rigid wall, but blood flows through a deformable elastic vessel. A few researchers have tried to simulate using fluid-structure interaction because an elastic wall implicates the decrease of wall shear stress inside the aneurysms. The current experimental model with the elastic wall has been carried out using part...
Developmental Venous Anomaly Adjacent to Aqueduct of Sylvius
Kenichi Nishiyama and Akira Hasegawa
Article Type: Case Report | First Published: May 13, 2016
A 15-year-old boy presented to our hospital with headache after head trauma caused by a traffic accident. T2-weighted axial MR-images demonstrated the deep medullary veins of the cerebellum converging on the roof of the fourth ventricle. These veins drained into the subependymal vein, which then drained into the precentral cerebellar vein (Figure 1). MR-cisternography with 3D Fourier transformation constructive interference in steady state (CISS), which can depict the venous anatomy when it is s...
Association of Severe Obesity with the Metabolic Profile of Adolescents and Adults
Jessica Socas Teixeira, Aline Bull, Silvia Elaine Pereira, Carlos Saboya and Andrea Ramalho
Article Type: Original Article | First Published: May 30, 2016
Objective: To evaluate, in adolescents and adults, the association of severe obesity with the extent of the metabolic changes shown. Methods: This is an observational comparative study with a population consisting of adolescents with severe obesity and adults with class III obesity. The patients underwent anthropometric, biochemical and clinical evaluations. We evaluated the lipid profile (total cholesterol, LDL-c, HDL-c and triglycerides), C-reactive protein (CRP) and fasting glucose. Insulin s...