Is Revisional Bariatric Surgery Effective as Primary Surgery?
Hakan Seyit, MD and Halil Alis, Professor
Article Type: Research Article | First Published: February 29, 2020
The study included randomly selected 350 PS patients for control group and 35 RS patients for study group. Prospectively-collected patient data were retrospectively reviewed. To measure the efficacy of the procedure, we calculated the excess weight loss percentage (EWL%). Effective weight loss was accepted as more than 50%. The changes in the status of the comorbid diseases, complications (leakage, bleeding and stenosis), weight loss, % excessive weight loss (EWL) and mortality were recorded. To summarize the first to systematically discuss results of primary surgery versus revisional surgery ...
Does Emu Oil Have a Role in the Relief of Non-Specific Pain? A Systematic Review of Clinical Trials Involving Emu Oil
David Sherwood, DO, Benjamin Gill, DO, MBA and Derick Schirmer, MS
Article Type: Original Article | First Published: March 13, 2020
Given a previous review on emu oil from 2014, which concluded a lack of clinical trial evidence, these authors set out to summarize the literature with regard to emu oil use for non-specific pain management. Non-specific pain management was selected as Google Trend data suggest that emu oil may be commonly amongst the general population for the treatment of non-specific pain. Using PRISMA guidelines, three randomized, controlled trial studies were identified, which found either no statistically significant difference between emu oil and placebo for pain relief or used a compound, which made it...
Teaching Communication Skills in Children and Adolescents with Severe To Profound Neurodevelopmental Disorders through Aided-Alternative and Augmentative Strategies
Article Type: Editorial | First Published: March 14, 2020
Children and adolescents with severe to profound neurodevelopmental disorders (e.g., attention deficit hyperactivity disorders, autism, cerebral palsy, rare genetic syndromes) may have intellectual, motor, and sensorial delays. Additionally, they may experience communication difficulties and exhibit isolation, passivity, and withdrawal. Challenging behaviors (e.g., aggression, impulsivity, stereotypic movements, and tantrum behavior) may occur. Their clinical conditions may seriously hamper their social desirability, image, and status with deleterious outcomes on their quality of life...
Effects of TSH on Erythrocyte Osmotic Fragility: Signaling Pathway
Evelyn Mendonca-Reis, Camila Cristina Guimaraes Nobre, Artur Paes-Chagas, Leandro Miranda-Alves and Clemilson Berto-Junior
Article Type: Original Article | First Published: March 09, 2020
TSH is a peptide hormone synthetized and secreted by pituitary with fundamental importance for thyroid function. TSH receptors are found in other tissue than thyroid playing diverse roles, including erythrocyte. Based on the fact that deformability is one of the most important features of a mature erythrocyte, we aimed to verify if TSH modulates erythrocytes volume and, if does, which signaling is involved in this modulation. Using hemolysis assay, we create a hemolysis curve of erythrocyte in presence of TSH in different concentrations (1, 2, 3 and 5 mIU/L). By adding AICAR, Wortmannin and Ak...
Successful Management of Hyperosmolar Hyperglycaemic State with Oral Hypoglycaemics in a Rural Setting - A Case Report
Jeremy Kay Hock Lee, Aaron Kwun Hang Ho and Lin Ho Wong
Article Type: Case Report | First Published: February 29, 2020
Hyperosmolar Hyperglycaemic State (HHS) is a diabetic emergency which requires prompt restoration of haemodynamic stability due to high early mortality. There is currently no study which recommends the use of oral hypoglycaemics to lower blood glucose levels, due to the high efficacy of parenteral Insulin. We report a case of our management of HHS using oral hypoglycaemics (Metformin and Gliclazide) due to the absence of parenteral Insulin in a rural setting, with remission of symptoms, stabilization of vitals and a significant decline in Random Capillary Blood Glucose (RCBG) levels in our pat...
Molecular Detection of Human Papilloma Virus Type 16 among Conjunctival Intraepithelial Neoplasia Patients in Khartoum State, Sudan
Hala H Ahmed, Aya A Almtry, Isra M Aidrous, Sara M Ali, Mohamed H Arbab and Ali M Badri
Article Type: Research Article | First Published: February 29, 2020
Many factors like exposure to UV radiation, climatic conditions, genetic predisposition, immunological state and, more recently, the presence of HPV have been implicated in the genesis of some lesions of the conjunctiva, especially the carcinoma. The study was carried out to detect Human Papilloma Viruses HPV type 16 in conjunctival intraepithelial neoplasia patient in Khartoum state, Sudan during the period from March to July 2019. A total of 50 Formalin-fixed paraffin- embedded Samples were collected from conjunctival intraepithelial neoplasia patients attending the Radiation-Isotopes Centre...
A Plausible "Penny" Costing Effective Treatment for Corona Virus - Ozone Therapy
Robert Jay Rowen, MD and Howard Robins, DPM
Article Type: Commentary | First Published: March 06, 2020
Many viruses require reduced sulfhydryl groups for cell fusion and entry. Corona viruses, including SARS-CoV-2 (the cause of the condition now named coronavirus disease 2019 or COVID-19), are rich in cysteine, which residues must be intact for viral activity. Sulfhydryl groups are vulnerable to oxidation. Ozone therapy, a very inexpensive and safe modality may safely exploit this critical vulnerability in many viruses, inclusive of SARS-CoV-2. Mainstream medicine has little in its arsenal for viral disease, and its therapies for bacterial infections are waning as well. Coronaviruses have abund...
Deferring Antibiotic Prescribing in Nursing Home Residents with Asymptomatic Bacteriuria: A Pilot Educational Intervention
Emilie Kennedy, DNP, CRNP, FNP-C
Article Type: Clinical Research Article | First Published: March 04, 2020
Unnecessary antibiotic use in nursing home patients leads to negative outcomes including the emergence of multi-drug-resistant bacteria, adverse drug events, polypharmacy and higher health care costs. The purpose of this study was to develop and assess the effects of a pilot clinical staff educational intervention on best practices for the management of asymptomatic bacteriuria (ASB) in nursing home residents. A multi-faceted educational intervention program on ASB was provided to Emergency Department clinical staff at Butler Memorial Hospital-a non-profit organization and independent communit...
Idiopathic Large Pericardial Effusion and Cardiac Tamponade in Children with Down Syndrome
Numra Aleem, MD, Amna Qasim, MD and Ashraf M Aly, MD, PhD
Article Type: Case Report | First Published: February 26, 2020
Pericardial effusions (PE) in patients with Down syndrome (Trisomy 21) have been associated with hypothyroidism, viral infections and malignancies (particularly leukemia). The PE is usually not large enough to cause cardiac tamponade. We report two cases of idiopathic large PE with one of them progressing to develop a cardiac tamponade that required an urgent pericardiocentesis. A 3-year-old female with Trisomy 21 was seen at cardiology clinic for follow up of a small secundum ASD. Patient has been asymptomatic from the cardiac standpoint and the parents denied any recent fever or other acute ...
Cannabinoid Use and Depression: Comparison of Natural and Synthetic Cannabinoids
Serap Akdeniz Gorgulu, MD and Can Sait Sevindik, MD
Article Type: Original Article | First Published: February 29, 2020
Patients who predominantly used marijuana (natural cannabis) and patients who predominantly used synthetic cannabinoids in their history were evaluated as two separate groups in our study which aimed to compare the sociodemographic characteristics and depressive symptoms of these two groups. The sample of our study consisted of those patients who referred to the Polyclinic of Psychiatry at Ardahan State Hospital and were diagnosed with substance addiction. 30 polyclinic patients who defined predominant use of marijuana and 20 polyclinic patients who defined predominant use of synthetic cannabi...