ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3419/1410132

A Novel Combined Methodology for Isolation and Detection of Circulating Tumor Cells based on Flow Cytometry and Cellular Filtration Technologies

Nikolaos G Grigoriadis, Konstantinos A Kyritsis, Melpomeni G Akrivou, Lefki-Pavlina N Giassafaki and Ioannis S Vizirianakis

Article Type: Original Article | First Published: February 08, 2020

Cancer cell presents a dynamic nature that evolves over time in its microenvironment through a complicating molecular and cellular interaction network. Despite the progress already achieved in the imaging technologies and the molecular tools used for tumor cell diagnosis and treatment approaches, metastasis still remains a major hindering factor that limits clinical outcomes. Circulating tumor cells (CTCs) present the potential in providing critical information to understand the metastasis process, the tumor cell and genome heterogeneity, in a way to overcome cancer therapy bottlenecks and imp...

 Open Access DOI:10.23937/2378-3419/1410131

Palmoplantar Erythrodysesthesia Associated with Capecitabine, Epidemiological Mapping and Risk Factors in Morocco

Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Brief Reports | First Published: January 27, 2020

A prospective cohort of a descriptive and analytical study, including sixty-one cases of Palmoplantar erythrodysesthesia in patients treated with capecitabine. The objective of this study is to determine an epidemiological mapping of Palmoplantar erythrodysesthesia in cancer patients on capecitabine treatment and to identify possible risk factors. The incidence of PPE was 64%. The median age of the patients who developed PPE was 54 years. 70% of the cohort was female, breast neoplasia represented 62% of all cases, 73% of these patients developed PPE. Colorectal neoplasia represented 27% of all...

 Open Access DOI:10.23937/2378-3419/1410130

Hyperpigmentation Associated with Anti-Tumor Chemotherapy: A Series of 54 Cases, Demo-Topographic Aspects and Interest of the Dermatological Intervention

Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Case Series | First Published: January 27, 2020

Three-year prospective study, from April 2016 to May 2019, including patients followed in oncology for malignant neoplasia, who developed hyperpigmentation following the start of antitumor chemotherapy for digestive, mammary and hematologic neoplasms, including the following molecules: 5 Fluorouracil, Tegafur, Cyclophosphamides, and Doxorubicin, in an isolated or combined mode. The study enrolled 54 patients, with an average age of 48 years and extremes ranging from 22 years to 67 years, with a sex ratio M/W of 1.2. The most affected phototypes were III and IV which accounted for 63% of cases....

 Open Access DOI:10.23937/2469-5866/1410033

Late-Life Alzheimer's Disease (AD) Detection Using Pruned Decision Trees

Gopi Battineni, Nalini Chintalapudi and Francesco Amenta

Article Type: Original Research | First Published: February 08, 2020

Machine Learning (ML) is a contemporary technique of artificial intelligence. These methods are exponentially rising in the medical field, especially in diagnosis and disease predictions. The present study was aimed to develop a decision tree model to predict late-life Alzheimer’s disease (AD). A dataset of 150 subjects along with 373 MRI sessions demographic values were considered in this paper. Pruned decision trees (J48) were employed to do predictive analysis on AD subjects. Model validation was conducted with cross fold (k = 10) methods. Performance measures were evaluated by accuracy, ...

 Open Access DOI:10.23937/2378-3656/1410296

Mixed Zone between Drug-Induced Hyperpigmentation and Generalized Fixed Pigmented Erythema

Tarik Hanafi, Amine Essaoudi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Case Report | First Published: January 31, 2020

We report a particular case of fixed drug eruption (FDE), in its erythematous and pigmented form, as a fixed pigmented erythema (FPE), which manifests in a generalized form, evolving for three years, and discuss the imputability to piroxicam and the Ramipril/Hydrochlorothiazide combination. Indeed, chronological, semiological, bibliographic criteria, were imprecise and non-discriminatory. We ended up retaining the diagnosis of fixed pigmented erythema (FPE) of particular diffuse presentation induced probably by piroxicam, based on clinical, histological and evolutive criteria. However, it rema...

 Open Access DOI:10.23937/2378-3656/1410295

Squamous Cell Carcinoma Complicating Hidradenitis Suppurativa in an HIV-Positive Patient

Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Case Report | First Published: January 27, 2020

Hidradenitis Suppurativa (HS), also called Acne inversa, is a Chronic inflammatory, suppurative, fistulizing disease, with a risk of malignant degeneration to squamous cell carcinoma (SCC). We report an intriguing case of a patient who developed an aggressive form of HS within a very short time of nine years, indeed, the patient was infected with the human immunodeficiency virus (HIV) and human papilloma virus (HPV). We believe that the oncogenic role of HPV was increased, given the very fast degeneration and propose a surgical cure at an earlier stage, particularly when a very close follow-up...

 Open Access DOI:10.23937/2378-3656/1410294

Non-Typhoidal Salmonella Meningitis in an Adult Patient with HIV Infection: The Hostage-Taking Situation. Is There Any Solution?

Tarik Hanafi, Hicham Titou, Hasna Kerrouch, Rachid Frikh, Naoufal Hjira and Mohammed Boui

Article Type: Case Report | First Published: January 25, 2020

We report a case of Non-Typhoidal Salmonella meningitis (NTS) in adult HIV patient with many relapses despite well-conducted treatment, we compare this situation to a hostage-taking situation, perpetrated by NTS, taking the body of HIV patient as a hostage who cannot get rid of this germ. This is a clinical alert to discuss the efficiency of prolonged oral administration of Trimethoprim/Sulfamethoxazole in preventing relapse and a whistleblower for the urgency of developing a vaccine....

 Open Access DOI:10.23937/2474-3682/1510141

Hemorrhagic Telangiectasia

Rkiouak, M Zaizae, I El Kassimi, N Sahel and Y Sekkach

Article Type: Image Article | First Published: February 13, 2020

A 45-year-old woman came to the internal Medical School A of Mohammed V Military Hospital, complaining of mild recurrent epistaxis related to telangiectasia at the nasal septum and chronic iron deficiency anemia requiring frequent blood transfusions with iron infusions. During his physical exam, we noticed telangiectasia lesions spread throughout her lower lip, tongue (Figure 1A), face, soft palate (Figure 1B) and outer ear (Figure 1C). Doing anterior rhinoscopy, we noticed hematic points on her septal mucosa and her right middle turbinate....

 Open Access DOI:10.23937/2474-3658/1510108

An Acute Gastroenteritis Outbreak Caused by Astrovirus Serotype 4 in a School of Shenzhen City, China, 2017

Luo Li, Li Yuan, Gao Zhiyong, Zeng Jinshui, Lian Yiyao, Song Wentao, Lv Bin, Chen Qi, Liu Na, Jin Miao, Liao Qiaohong, Wu shuyu, Li Zhongjie, Shi Guoqing and Ran Lu

Article Type: Research Article | First Published: January 29, 2020

Human astrovirus (HAstV) was first detected by Appleton and Higgins in 1975 in association with an outbreak of acute gastroenteritis in a maternity ward in England, and the same year named by Madeley and Cosgrove because of its star-like appearance. Astrovirus along with rotavirus, norovirus and sapovirus, is recognized as a common cause of viral acute gastroenteritis in adults and children. Similarly, with other enteric pathogens, the main clinical symptoms of astrovirus are vomiting, diarrhea, abdominal cramps and nausea. However, incubation period varies within those common enteric viruses ...

 Open Access DOI:10.23937/2474-3658/1510107

Influence of Land Cover and Host Species on Trypanosome Infection in Cattle and its Socio-Economic Impacts to Pastoralists of the Maasai Steppe, Tanzania

Kelvin Ngongolo, Gabriel Shirima, Emmanuel A Mpolya, Anna B Estes, Peter J Hudson and Paul S Gwakisa

Article Type: Research Article | First Published: January 29, 2020

We undertook a cohort field study in three villages of the Maasai Steppe: Sukuro, Kimotorok and Oltukai. The study took place in July 2017 and October 2017 and utilized 50 cattle from each village. Pastoralists were asked questions during each visit when blood sampled were taken to seek their viewpoint on the relative abundance of wildlife, habitat types and cultivation observed in the areas their cattle grazed. In addition, the percentage cover of cultivated land and habitat types in the grazing areas were determined during field visits and participatory mapping with pastoralists. A systemati...

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Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

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International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

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International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

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International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

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Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

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International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin