Prevention of Frailty in the Elderly through Physical Activity and Nutrition
Brunilda Elezi, Erjona Abazaj, Marsida Kasa and Skender Topi
Article Type: Research Article | First Published: January 27, 2020
Frailty is considered often as a physical impairment in the elderly and its characteristics are weakness, weight loss, exhaustion, a decrease of the physical activity accumulating also comorbidity. It is considered the geriatric syndrome related to the aging process, declining of biological reserve that results in an increase of vulnerability for negative results including disability, hospitalization, and death. Frailty was defined as “a state of increased vulnerability on the stress factors due to the decline of the neuromuscular, metabolic, physiologic reserve and immune systems....
Albumin, Important Therapy & When to Use It in Ten Patients (Adult & Child): Case Report
Nathasia and Sukmawati Tansil Tan
Article Type: Case Report | First Published: February 03, 2020
Toxic epidermal necrolysis (TEN) is a life-threatening drug reaction that requires immediate medical treatment. Mortality due to TEN cases is quite high until now and the main cause reported is multiple organ dysfunction syndrome. A 7-year-old child, was diagnosed TEN with 86% blistered skin, after receiving Metampiron. Given 20% albumin 50 ml from the first day treated until 20 days, also fluid resucitation, steroids, antibiotics, vitamin C, neurobion, paracetamol, antihistamines, oral hygiene, steroid and antibiotic ointment for body, eye ointment, woundcare, and high nutritions....
Pre-Twin Screen - A Multi-Disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies
Hamutal Meiri, Nadav Kugler, Ran Svirsky, Oliver Kagan, Richard Nicolas Brown, Piere Miron, Antoni Borrell, Anna Gonce, Mar Bennasar, Annegret Geipel, Brigitte Strizek, Argyro Syngeleki, Kypros Nicolaides, Howard Cuckle and Ron Maymon
Article Type: Research Article | First Published: January 30, 2020
The prevalence of twin pregnancies is rising globally due to increased assisted conception and advanced maternal age in pregnancy. Twin pregnancies have 5-9 times higher frequencies of fetal chromosomal and structural abnormalities, often deliver preterm, and have high prevalence of gestational diabetes mellitus (GDM), preeclampsia (PE), and intrauterine growth restriction (IUGR) compared to singletons. Twins have special complications such as twins-to twin transfusion syndrome in mono chorionic (MC) twins. Consequently, more twins are born prematurely, suffer from low birth weight, cerebral p...
In Vivo Small Bowel Length is Longer than in Formalin-Fixed Cadavers
Randal Zhou, MD, Bruce A Orkin, MD, FACS, FASCRS, James M Williams, PhD, Anthony Serici, BS, Jennifer Poirier, PhD, Walid El-Bermani, MBChB, PhD, Ronald Bohn, PhD and Areta Kowal-Vern, MD, FCAP, FASCP
Article Type: Research Article | First Published: February 03, 2020
Surgeons require accurate ranges of normal small bowel length (SBL) to benefit patients. The relationship between cadaveric SBL and in vivo human SBL is not known. We hypothesized that cadaveric SBL is significantly different compared to human SBL. SBL was measured prospectively in 167 formalin- fixed cadavers; and studied in 118 without intestinal surgery. A standardized and reproducible method of small bowel measurement was utilized in both in vivo and cadaveric subjects. Small bowel was measured in situ from the Ligament of Treitz to the ileocecal valve. These measurements were compared to ...
A Scientometric Study of Research Pertaining to the RASopathies Conditions: Costello Syndrome, Noonan Syndrome, Cardiofaciocutaneous Syndrome, Capillary Malformation-Arteriovenous Malformation Syndrome, and Legius Syndrome
Ting Wang and Brady Lund
Article Type: Research article | First Published: February 01, 2020
RASopathies is one of the largest known groups of malformation. Which affects 1 in 1,000 individuals in general. As a critical part of the genetic disorder research and the existing gaps in current research, a bibliometric study of the existing body of RASopathies condition is needed. Online retrieval from the Web of Science (WoS) database was performed. The collected data were analyzed by the Excel and VosViewer to identify the top authors, top journals, main themes in RASopathies, and the trend in annual research productivity about the RASopathies condition....
Effect of CoQ10 Supplementation on Oxidative Stress and Muscle Bioenergetics in Type II Diabetes: A Pilot Study
Joohee Sanders, PhD, Sinclair Smith, PhD and Carsten Sanders, PhD
Article Type: Original Article | First Published: January 30, 2020
To compare oxidative stress, mitochondrial oxidative phosphorylation capacity, microvascular function, and exercise performance of type II diabetics (T2D) to that of control subjects and to determine whether Co-enzyme Q10 (CoQ10) supplementation has any effects on these measures. Noted reduction in MDA seen in healthy, older individuals suggests a positive antioxidant effect of CoQ10 supplementation. However, when PAD is present, as can be the case of T2D, two weeks of CoQ10 supplementation at 200 mg·day-1 may not be long enough or potent enough to produce similar effects....
Prevalence of Hepatitis C Virus and Other Comorbidities in Dialysis Population of Elbasan City, Albania
Elezi Brunilda, Topi Skender, Abazaj Erjona, Bolleke Erjola and Kasa Marsida
Article Type: Research Article | First Published: January 27, 2020
Hepatitis C virus (HCV) infection is associated with increased morbidity and mortality among patients on dialysis (HD). The aims of this study were to estimate the presence of HCV and other comorbidities in the dialysis population of Elbasan city, and to compare the survival outcomes of those patients who started dialysis with haemodialysis and peritoneal dialysis. In the present study, we have used a socio-demographic questionnaire to collect data from HD patients. We studied 108 dialysis patients in dialysis Centre for 1 year. Software SPSS version 20.0, were used to analyzed and evaluate th...
Pre-analytical Errors in the HIV Anti Retro Viral Therapy (ART) Laboratory of Teaching Referral Hospitals in Addis Ababa, Ethiopia
Abay Sisay Misganaw, Mulugeta Worku, Chala Bashea, Mamaru Nigus, Yisak Yoseph, and Habtamu Molla
Article Type: Brief Report | First Published: October 18, 2019
To assess the magnitude and associated factor of pre-analytical error in the Human Immunodeficiency Virus (HIV) antiretroviral therapy (ART) laboratory of a teaching referral hospitals in Addis Ababa, Ethiopia. A cross-sectional descriptive study design was used from May 1, 2018 to Jun 30, 2018 by using both quantitative and quantitative data collection approach. Data was entered, cleaned using Statistical Package for the Social Science (SPSS) version 21 for Microsoft Windows. Among the 427 specimens submitted for laboratory testing, 41 (9.6%) were not accepted for requested laboratory diagnos...
The Blood Levels of the Amino Acid Kynurenine and Indoloxigenase are Predictive of Acute Graft Versus Host Disease (aGVHD)
Ferreira DC, Silva IDCG, Lo Turco EG and Oliveira JSR
Article Type: Research article | First Published: January 25, 2020
The main barrier to the success of hematopoietic stem cell transplantation (HSCT) is acute graft versus host disease (aGVHD). The risk factors for aGVHD are mainly clinical and can be improved if additional biological factors are incorporated, such as the metabolomic profile. It is known that the levels of various metabolites measured are important in the process of immunoregulation. In our population study we investigated the systemic metabolic profile for 26 (Group I) allotransplant recipients. The metabolomics study was carried out by Targeted Mass Spectrometry. Plasma samples of the 26 pat...