ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3001/2/2/1033

Cognitive Impairment and the Diabetic Brain

Kurt A Jellinger

Article Type: Mini Review | First Published: October 12, 2015

Alzheimer's disease (AD) and diabetes mellitus (DM) are the two most common and devastating health problems in the elderly. DM is a known risk factor for the development of cognitive dysfunction and dementia. Epidemiological and biological evidences support a link between type 2 DM (T2DM) and AD, but the precise mechanisms involved in the development of cognitive impairment in diabetics are not fully understood. Possible pathogenic pathways include genetic factors, ageing, ApoE status, hypo- and hyperglycaemia, cardiovascular risk factors, hypertension, obesity, multimorbidity and other factor...

 Open Access DOI:10.23937/2378-3001/2/2/1032

Citicoline Treatment Improves Measures of Impulsivity and Task Performance in Chronic Marijuana Smokers: A Pilot BOLD fMRI Study

Staci A. Gruber, Kelly A. Sagar, Mary Kathryn Dahlgren, Atilla Gonenc, Nina A. Conn, Jeffrey P. Winer, David Penetar and Scott E. Lukas

Article Type: Original Research Article | First Published: September 10, 2015

Citicoline is an endogenous nucleotide that has historically been used to treat stroke, traumatic brain injury, and cognitive dysfunction. Research has also shown that citicoline treatment is associated with improved cognitive performance in substance-abusing populations. We hypothesized that marijuana (MJ) smokers who received citicoline would demonstrate improvement in cognitive performance as well as increased neural efficiency during tasks of cognitive control relative to those who received placebo....

 Open Access DOI:10.23937/2572-3235.1510004

Visualization of Vascular Anastomosis as Responsible Sites of Hemoptysis by Three-Dimensional Angiography for the Guidance of Endovascular Treatment

Kembu Nakamoto, Hiroshi Hashiyada, Toshiyuki Fujii, Motohiro Takeshige, Kazuya Yoshida and Kaido Ooishi

Article Type: Case Report | First Published: October 22, 2015

The major site of bronchial hemorrhage in inflammatory hemoptysis is vessel anastomoses (VA) between pulmonary and systemic arteries. Three-dimensional computed tomographic angiography (3D-CT angio) was applied to depict VA for accurate access in endovascular treatment (EVT) for two patients with bronchiectasis. Fusion of the images of pulmonary and systemic 3D-CT angio visualized VA of potential hemorrhagic bronchi. VA depiction allowed successful EVT for hemoptysis with exclusion of non- responsible vessels....

 Open Access DOI:10.23937/2572-3235.1510003

A Case of Spontaneous Bacterial Peritonitis after Radiofrequency Ablation of an Early Hepatocellular Carcinoma

Pierleone Lucatelli, Beatrice Sacconi, Emanuele Arcangelo d'Adamo, Carlo Catalano and Mario Bezzi

Article Type: Case Report | First Published: September 14, 2015

Radiofrequency ablation (RFA) is frequently used to treat small hepatocellular carcinoma (HCC), with similar outcome to surgery. The procedure is relatively safe, with low morbidity and mortality rates. The most common major complications are both intra-hepatic (bleeding, abscess and biliary injury) and extra-hepatic (peritoneal bleeding, gastrointestinal perforation, pleural effusion). We report a successfully managed case of spontaneous bacterial peritonitis (SBP) after RFA of a left liver lobe HCC....

 Open Access DOI:10.23937/2572-3278.1510008

Nutritional Intake and Cardiovascular Risk Factors in Saudi Subjects with Different Degrees of Atherosclerosis: A Case Control Study

Eman M Alissa and Nabeel A Alama

Article Type: Original Article | First Published: October 14, 2015

Coronary heart disease (CHD) is related to a large number of environmental and lifestyle factors including an unhealthy dietary pattern, physical inactivity and a positive smoking habit. Dietary modification has been involved in managing and reducing the risk of CHD. We aimed to assess the dietary intake of Saudi population with various degrees of atherosclerosis, and to examine the relationship between specific nutrient intakes with some classical cardiovascular risk factors. ...

 Open Access DOI:10.23937/2572-3278.1510007

The Importance of Nutritional Control and Diet Care in Huntington's Disease

Nieves Gonzalez

Article Type: Editorial | First Published: September 28, 2015

The first descriptions of chorea, from the Greek word 'dance', date back to the middle ages. The condition 'Saint Vitus dance' was initially considered a curse, and was named so, because afflicted individuals were 'cured' when they touched churches, which enshrined Saint Vitus relics. In 1872, Dr. George Huntington published a report entitled 'On chorea', where he characterized the Huntington's disease (HD) as a genetic condition, which specifically causes degeneration in neurons of the striatum, resulting in a triad of symptoms, and also including emotional alterations and motor impairments.....

 Open Access DOI:10.23937/2572-3278.1510006

Active Hexose Correlated Compound Activates Immune Function to Decrease Chlamydia trachomatis Shedding in a Murine Stress Model

Tesfaye Belay, Chih-lung Fu and Anthony Woart

Article Type: Original Article | First Published: September 15, 2015

A cold-induced stress mouse model for investigating chlamydia genital infection and immune response analysis was established in our laboratory. Previous results showed that cold-induced stress results in suppression of the immune response and increased intensity of chlamydia genital infection in the mouse model. The purpose of the present study was to evaluate the potential therapeutic value of active hexose correlated compound (AHCC) against chlamydia genital infection in mice. AHCC is an extract of mushroom commonly used as a dietary supplement is known to boost the immune system. Mice were ...

 Open Access DOI:10.23937/2572-407X.1510003

Hypercalcemia, an Uncommon Presentation of Hyperthyroidism

Fathimabeebi PK, Noor Bader Al Busaidi and Mohamed Al Lamki

Article Type: Case Report | First Published: October 13, 2015

Background: Moderate to severe hypercalcemia associated with hyperthyroidism is not very common and can raise a diagnostic challenge to the treating physician. Objective: To present a case of thyrotoxicosis manifested with symptoms of hypercalcemia and resolution of symptoms after rendering euthyroid. Method: We report the case of a 61 year old Omani gentleman, who presented with symptoms of hypercalcemia like weight loss (10 kg) with poor appetite, constipation and depression as first manifestation of hyperthyroidism....

 Open Access DOI:10.23937/2572-407X.1510002

Growth-Differentiation Factor-15 at Risk Stratification in Diabetes Patients: Usefulness, Discrepancies, and Hype

Alexander E. Berezin

Article Type: Mini Review | First Published: September 17, 2015

Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine, which belongs to super family of the transforming growth factor beta. GDF-15 is widely presented in the various cells (macrophages, vascular smooth muscle cells, adipocytes, cardiomyocytes, endothelial cells, fibroblasts), tissues (adipose tissue, vessels, tissues of central and peripheral nervous system) and organs (heart, brain, liver, placenta) and it plays an important role in the regulation of the inflammatory response, growth and cell differentiation....

 Open Access DOI:10.23937/2378-3664/1410012

Bio-Active Designer Materials and Dentures: from Design to Application

V Tamara Perchyonok, John Souza, Shengmiao Zhang, Desigar Moodley and Sias Grobler

Article Type: Research Article | First Published: November 02, 2015

The bio-active modified polymethyl methacrylate denture resins (PMMA) were prepared by dispersion of the corresponding component in glycerol and acetic acid with the addition of chitosan gelling agent. The release behaviors at physiological pH and also under acidic conditions and stability of the antioxidant-chitosan were also evaluated. Mechanical performance such as tensile strength and compressive strength were measured as well bio-adhesive studies were investigated in order to assess the suitability of these designer materials....

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Role of Oxidative Stress and Apoptosis in the Hepatic Toxicity Induced by Cerium Oxide Nanoparticles Following Intratracheal Instillation in Male Sprague-Dawley Rats

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