ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2378-346X/1410029

Treatment of a Pseudoxanthoma Elasticum Patient Initially Presented with Choroidal Neovascularisation Secondary to Angioid Streaks

Muhammed Sahin, Alparslan Sahin, Harun Yuksel, Umit Peker and Fatih Mehmet Turkcu

Article Type: Case Report | First Published: July 20, 2015

Pseudoxanthoma elasticum (PXE) is a rare, systemic disease with typical ophthalmological findings including angioid streaks (AS) (represent breaks in the Bruch's membrane). A serious and common complication of AS is the development of choroidal neovascularization (CNV), which can result in significant and irreversible vision loss. The introduction of intravitreal agents that inhibit vascular endothelial growth factor (VEGF) has improved outcomes in patients with CNV. In this paper we aimed to present a 33-years-old woman with PXE. The patient had CNV in the left eye secondary to AS and was tre...

 Open Access DOI:10.23937/2469-5718/1510014

Effect of Hypercapnic Severity on Plasma Ammonia Accumulation and Respiratory Exchange Ratio during Incremental Exercise

Takahide Kato, Takaaki Matsumoto, Atsuko Tsukanaka, Masataka Nakano, Ryo Ito, Masato Amano, Marc Cole and Stanley M Yamashiro

Article Type: Original Investigation | First Published: July 20, 2015

Blood lactate (La) and ammonia (Am) concentrations are widely accepted markers of metabolism not only in clinical studies but also during exercise. Elevations from normal resting levels of both are observed in exercise and associated with deleterious effects such as fatigue. A decrease in blood La concentration during exercise under hypercapnic conditions was previously reported, and La threshold (LT) was unchanged by hypercapnia....

 Open Access DOI:10.23937/2378-346X/1410028

Acute Ophthalmic Artery Occlusion as Initial Manifestation of Acquired Immunodeficiency Syndrome

Gowtham Jonna, Matthew SJ Katz, David M Rubaltelli, David C Gritz and Peter L Gehlbach

Article Type: Case Report | First Published: July 20, 2015

Purpose: To report the first case of acute ophthalmic artery occlusion as initial manifestation of Acquired Immunodeficiency Syndrome (AIDS) in context of marked Human Immunodeficiency Virus-1 (HIV-1) viremia and otherwise negative work-up. Methods: Report of a 25 year-old previously healthy man who presented to a hospital-based tertiary care referral center with acute, monocular vision loss. Complete ophthalmologic examination, fluorescein angiography, and full systemic evaluation were performed....

 Open Access DOI:10.23937/2469-5734/1510010

Immediate Implant Placement in the Infected Site with Presence of a Pre-Existing Cyst: Report of Two Cases

Binbin Yu, Chun Fan, Ximei Xiao, Jiajia Song, Chenglong Ji and Chunyang Zhang

Article Type: Case Report | First Published: July 24, 2015

This report showed that the placement of immediate implants in presence of a pre-existing infected cyst may not be necessarily contraindicated if appropriate clinical procedures like antibiotic administration, meticulous cleaning, and alveolar debridement are performed before implant surgical procedure. Immediate placement of implants for replacement of teeth with the pre-existing infected cysts is a predictable treatment and can be indicated for replacing teeth lost. This report regards the immediate placement of an implant into a residual cyst; some anatomical, surgery techniques, clinical a...

 Open Access DOI:10.23937/2378-3516/1410023

Chronic Rhinosinusitis is Associated with Airflow Obstruction in Japanese Never-Smokers without Asthma

Keita Matsumoto, Tomotaka Kawayama, Takashi Kinoshita, Shuwa Minami, Kazuko Matsunaga, Masako Nagafuchi, Tomoaki Hoshino and Toru Rikimaru

Article Type: Original Article | First Published: July 22, 2015

Background: The relationship between chronic rhinosinusitis (CRS) and airflow obstruction is still unclear. This cross-sectional study was conducted to investigate whether CRS is an independent risk factor for airflow obstruction in never-smokers without asthma. Methods: One hundred fifty-eight subjects aged ≥ 40 yr without asthma were divided into 4 groups: 22 never-smokers with CRS, 27 smokers with CRS, 69 never-smokers without CRS, and 40 smokers without CRS. Subjects with airflow obstruction were compared among the groups, and the correlation between CRS severity and airflow obstruct...

 Open Access DOI:10.23937/2572-3278.1510004

Differences in Dietary Components and Oxidative Stress Markers between Cervical Cancer Patients and Matched Controls

Gabriela Gutierrez-Salmean, Mayra Acosta, Fabiola Arellano, Karolina Alvarez Altamirano, Veronica Ruiz-Manon, Guillermo M Ceballos-Reyes and Vanessa Fuchs Tarlovsky

Article Type: Review Article | First Published: July 03, 2015

Cervical cancer is a leading cause of death among women in developing countries. Diet has been suggested to play an important role in the pathophysiology of malignant tumors as an imbalance between dietary antioxidant intake and free radical production-from the inflammatory state results in oxidative stress, which may contribute to both initiation and progression of carcinogenesis. The aims of the present study were to assess the difference regarding dietary intake and oxidative stress plasmatic markers differences between cervical cancer patients and matched controls....

 Open Access DOI:10.23937/2378-3516/1410022

Management of a Refractory Malignant Pleural Effusion in a Patient with Small Cell Lung Cancer: A Case Report

Maria M Wilczynska and Helen E Davies

Article Type: Case Report | First Published: July 20, 2015

Malignant pleural effusion (MPE) is a common presenting feature of underlying malignancy and frequently results in debilitating symptoms. In chemosensitive malignancies, such as lymphoma, small cell lung or ovarian cancers, chemotherapy is often considered the fist line treatment, however if unsuccessful, pleural intervention to achieve fluid control is required. This may include therapeutic thoracentesis, chest drain insertion, thoracoscopy, chemical pleurodesis, and use of an ambulatory indwelling pleural catheter (IPC) or a combination of the above procedures....

 Open Access DOI:10.23937/2378-3516/1410021

Reference Values of Pulmonary Function Tests for Rural Canadians

Chandima P Karunanayake, James A Dosman, Louise Hagel, Donna C Rennie, Joshua A Lawson, Punam Pahwa and Saskatchewan Rural Health Study Group

Article Type: Original Research Article | First Published: June 22, 2015

Background: Pulmonary function tests are used routinely to evaluate patients with respiratory diseases and those who are at risk of developing respiratory diseases. Lung function prediction equations are generally developed for urban populations and whether these differ on rural population is not well studied. There is limited information on prediction equations for rural populations. Objective: The purpose of the present study was to derive prediction equations for commonly used pulmonary function tests in a rural Canadian Caucasian population and to examine whether results of tests were comp...

 Open Access DOI:10.23937/2377-9004/1410050

Diagnosis and Management of Embryonal Rhabdomyosarcoma in a Woman with Prolapsing Cervical Mass

Elizabeth V. Connor and Paul A. Disilvestro

Article Type: Case Report | First Published: July 10, 2015

Background: Cervical rhabdomyosarcoma is very rare, comprising less than 1% of cervical cancers in adult women. Less than 40 cases of cervical rhabdomyosarcoma have been reported in adult women in the last 50 years. Due to the rarity of this disease, management guidelines are non-existent. Case: We present a 36-year-old woman who presented with pelvic pain and a vaginal mass. The mass was excised, and pathology confirmed poorly differentiated embryonal type rhabdomyosarcoma....

 Open Access DOI:10.23937/2378-3001/2/2/1029

Clock Drawing Test (CDT): is Qualitative Analysis of the CDT Better to Screen Mild Cognitive Impairment than Quantitative Analysis?

Ji Hee Lee, Eung Seok Oh, Eun Hee Sohn and Ae Young Lee

Article Type: Original Article | First Published: July 06, 2015

Mild cognitive impairment (MCI) was originally used to describe a transitional state between normal condition and dementia. Revised and extended definition of MCI has been proposed that covers a broader range of cognitive impairment, distinct from normal ageing and from Alzheimer's disease. Despite the existence of reports regarding analyses of the Clock Drawing test (CDT) in Alzheimer's disease and vascular dementia, those focusing on MCI subjects are still lacking. The purpose of this study was to assess the characteristics of CDT and compare the results of quantitative and qualitative analy...

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