ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

4
1
9
5

Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2377-3634/1410012

Qualitative Research: A pathway to Gain an Understanding of UAE Mothers' experiences and Perceptions of Managing a Child Newly Diagnosed with Type 1 Diabetes

Jennifer Louise Cooper, Suhad Marjei, Rachel Rossiter and Sharon Brownie

Article Type: Research Article | First Published: November 25, 2014

A childhood diagnosis of Type 1 diabetes is a life changing event for both the child and his/her family. The impact is experienced strongly by mothers who most frequently fulfil the primary caregiver role for children12 yrs old and younger. Studies which have sought to understand mothers' experiences and perceptions of managing a child newly diagnosed with Type 1 diabetes are mostly questionnaire-based and few, if any, explore the issues within the uniqueness of a Middle-Eastern context. The qualitative research methods described in this discussion have been designed to gain a better understan...

 Open Access DOI:10.23937/2378-3001/1/1/1012

Randomised Clinical Trial Comparing the Efficacy of A Gluten-Free Diet Versus A Regular Diet in A Series of Relapsing-Remitting Multiple Sclerosis Patients

Rodrigo L, Hernandez-Lahoz C, Fuentes D, Mauri G, Alvarez N, Vega J and Gonzalez S

Article Type: Original Article | First Published: December 08, 2014

Objectives: To analyse the clinical efficacy of a Gluten-Free Diet (GFD) compared with a Regular Diet (RD) in Relapsing-Remitting Multiple Sclerosis (RRMS) patients. Methods: Seventy-two RRMS patients were included into a prospective study. Annual relapse rate (ARR), Expanded Disability Status Scale (EDSS) and lesional activity were compared. Patients were randomly separated according to diet: (GFD, n=36) and (RD, n=36). Follow-up study period was 5.3 1.6 years (median 4.5 years). Results: At the end of the study period, a clear improvement in the EDSS was observed in GFD (1.5 1.4) com...

 Open Access DOI:10.23937/2378-3001/1/1/1011

D-Leucine Suppresses Prion Formation in Prion-Infected Culture Cells

Kana Miyashita, Morika Suzuki, Kana Nishijima and Naomi Hachiya

Article Type: Short Communication | First Published: November 24, 2014

Prion disease is an infectious and fatal disease. The pathogen consists of an abnormal form of the prion protein; designated PrPSc. PrPSc is insoluble, highly resistant to digestion by proteases and all disinfectants. In contrast, the cellular form of prion protein PrPC is easily soluble and digested by proteases. Direct interaction between PrPSc and PrPC is believed to induce the propagation of prions; however, the molecular mechanisms underlying this step have not been clarified. Despite efforts to find molecules that can specifically interact with the prion protein conformer and thereby inh...

 Open Access DOI:10.23937/2378-3648/1410007

Variation H452Y in HTR2A Gene Effects Immediate Visual Memory

Nesli Avgan, Heidi G. Sutherland, Lauren K. Spriggens, Astrid J. Rodriguez-Acevedo, Larisa M. Haupt, David H. K. Shum and Lyn R. Griffihs

Article Type: Research Article | First Published: November 12, 2014

Serotonin and its receptors, including the 5-Hydroxytryptamine Receptor 2A encoded by the HTR2A gene, are important for learning and memory in animals and humans.Polymorphic variation in the HTR2A gene, which encodes the 5-HT2Aserotonin receptor, has previously been shown to associate with some memory traits,in particular effecting delayed verbal memory. In the current study we have examined the HTR2A His452Tyr (H452Y) substitution for association in a cohort of healthy individuals whose memory traits were assessed using a comprehensive battery of memory tests including, but not limited to, me...

 Open Access DOI:10.23937/2469-567X/1510003

Modification of Antiretroviral Therapy in a Cohort Study of HIV-Infected Patients Attending an Urban Teaching Hospital in Kenya

AO Owuor, GN Lule, CF Otieno, EO Omonge, MC Maritim and P Memiah

Article Type: Research Article | First Published: November 28, 2014

Objective: To determine the prevalence and factors associated with ART modification among HIV patients on 1st line therapy attending a large Teaching Hospital in Kenya. Methods: A retrospective cross-sectional clinical record review. All patients who commenced ART from January 2005 to June 2011 and had at least 1 follow-up visit were evaluated. Baseline data, including socio demographic and clinical variables was collected using a standard chart abstraction tool. Results: Out of 1,022 patients 658 (64.4%) were female and the mean age of study participants was 37.8years. The median CD4+ cou...

 Open Access DOI:10.23937/2469-567X/1510002

Prognostic Value of Some Acute Phase Reactants in the Management of Pulmonary Tuberculosis Disease

Akpotuzor Josephine O, Ekarika Evelyn A and Akwiwu Euphoria C

Article Type: Research Article | First Published: November 16, 2014

This study was conducted to assess the relevance of serum C- reactive protein (CRP), erythrocyte sedimentation rate (ESR), relative plasma viscosity (RPV) and fibrinogen level in the management of pulmonary tuberculosis (PTB) disease. One hundred (100) PTB patients attending the TB clinic of Dr Lawrence Henshaw Memorial Specialist Hospital Calabar, and 70 age and sex-matched apparently healthy subjects between 15-65 years of age were selected and enrolled. Standard techniques were used for the assays. Results showed significantly lower PCV (p<0.05) in PTB patients (0.35 0.07L/L) when compare...

 Open Access DOI:10.23937/2378-3648/1410006

Identification of Ten Novel Mutations in Factor VIII Gene: A Study of A Cohort of 52 Haemophilia A Patients

Rosa Santacroce, Angelica Leccese, Roberta Trunzo, Giuseppe Lassandro, Paola Giordano, Cosimo Ettorre, Stefano Antoncecchi, Isabella Cantori, Alfredo Dragani, Donata Belvini, Roberta Salviato and Maurizio Margaglione

Article Type: Research Article | First Published: October 14, 2014

Introduction: Haemophilia A (HA) is the most common X-linked recessive genetic disease caused by mutations in the gene coding for coagulation factor VIII (FVIII) resulting in spontaneous bleeding. Aim: The aim of our study is to provide additional information about the genetic causes of HA describing the correlation between the observed mutations and the clinical phenotype in a cohort of 52 patients suffering from HA to different degrees. Methods: First we performed a search of inversion 22 (IVS22) and of the intron 1 (IVS1) for severe HA patients; inversions negative and moderate/mild HA ...

 Open Access DOI:10.23937/2377-4630/1/3/1013

Allergy to General Anesthetics: Evaluation of Patients Profile

Carla Irani, C. Saade, C. Dagher and P.Yazbeck

Article Type: Original Article | First Published: November 02, 2014

8 millions procedures requiring anesthesia are performed yearly in France with 75% of them being general anesthesia. In 45% of those procedures, a NMBA (neuromuscular blocking agents) is used. Th incidence of allergy to general anesthetics ranges between 1/20000 in Australia and 1/350 in Great-Britain. Th incidence of peranesthestic allergic reactions estimated in 1996 in France was 1/9000, all drugs confounded and the incidence of allergic reactions to NMBA was evaluated to be 1/6500 anesthesia. Allergic reactions can be benign or fatal in some cases (6%), presenting with urticaria /angioedem...

 Open Access DOI:10.23937/2377-3634/1410011

Assessment of Learning Guides Improvement in Diabetes Education Program: A QI Initiative for Type I Diabetes Mellitus in Children and Adolescents

Manmohan K. Kamboj, Kathryn J. Stephens, Richard J. Brilli, Heather L. Yardley, Jeff Lewis, Richard E. McClead, Jr. and David R. Repaske

Article Type: Research Article | First Published: November 17, 2014

Aims: To develop objective assessment tools to evaluate proficiency of well-day (WD) and sick-day (SD) diabetes knowledge and management skills in families of pediatric type 1 diabetes patients and to utilize this information to modify our diabetes education (DE) program to improve learning of the desired knowledge and skills. Methods: Vignette-based assessment quizzes were developed to evaluate WD and SD diabetes knowledge and management skills. Vignettes assessed basic knowledge and skills including calculation of insulin doses, treatment of hypoglycemia, and management of hyperglycemia an...

 Open Access DOI:10.23937/2377-3634/1410010

Type 2 Diabetes and Lifestyle- A Prospective Population-Based Cohort Study among Rural Men

Anders Thelin and Sara Holmberg

Article Type: Research Article | First Published: November 16, 2014

The risk of type 2 diabetes (T2D) is related to lifestyle but less is known about how lifestyle factors interact and how they impact the risk when combined. This study was performed to analyze how lifestyle factors relate to the cumulative incidence of T2D in a Swedish rural population. Outcomes were generated from national registers and from two surveys. Two hundred sixty men (11%) with diabetes were found in the registers, and 193 men with T2D were identified in the surveyed population (9.8%). Physical activity (OR for high physical activity=0.55 (95% CI 0.31-0.97) and meal quality (OR for h...

Why ClinMed?

Preservation of author's rights
Global followership
Noncommercial objectives
Neutral and unbiased publishing process
Reprints issued accross the world
Timely submission for indexing
Published with CrossMark® policy

Editors' Picks

Can Genetic Testing Provide Information to Develop Customized Nutrigenomic..
Pubmed ID:26225358 | PMC ID:PMC4516390
Acute Ovarian Insufficiency and Uterine Infarction Following Uterine Artery..
Pubmed ID:26523290 | PMC ID:PMC4623578
Challenges of Fertility Sparing Ovarian Surgery Imposed by Krukenberg..
Pubmed ID:26366440 | PMC ID:PMC4563814
Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral..
Pubmed ID:27398405 | PMC ID:PMC4936830
Hypothesizing that a Pro-Dopaminergic Regulator (KB220z™ Liquid Variant)..
Pubmed ID:29034323 | PMC ID:PMC5638455
Titanates and Titanate-Metal Compounds in Biological Contexts..
Pubmed ID:26430701 | PMC ID:PMC4587770
MyHEART: A Non Randomized Feasibility Study of a Young Adult..
Pubmed ID:28191544 | PMC ID:PMC5300088
Exenatide Effects on Cardiometabolic Risk and Weight in Adolescents..
Pubmed ID:27182560 | PMC ID:PMC4864000
A New Animal Model to Study Endogenous Cardiotonic Steroids and the Progression..
Pubmed ID:26457335 | PMC ID:PMC4599712
Common Genetic Variation in Circadian Rhythm Genes and Risk of..
Pubmed ID:26807442 | PMC ID:PMC4722961
Active Hexose Correlated Compound Activates Immune Function to Decrease..
Pubmed ID:27790645 | PMC ID:PMC5079436
The Extraction, Anticancer Effect, Bioavailability, and..
Pubmed ID:27790646 | PMC ID:PMC5079443
Kyphosis and Sleep Characteristics in Older Persons: The Rancho..
Pubmed ID:28480455 | PMC ID:PMC5419044
Suppression of Experimental Arthritis through AMP-Activated Protein..
Pubmed ID:26120598 | PMC ID:PMC4479345
Aspirin-Triggered Resolvin D1 Versus Dexamethasone in the Treatment of..
Pubmed ID:27110599 | PMC ID:PMC4841619
Elder Mistreatment and its Subtypes across Different Sociodemographic and..
Pubmed ID:26973979 | PMC ID:PMC4786076
Balance and its Clinical Assessment in Older Adults - A Review..
Pubmed ID:26942231 | PMC ID:PMC4773046
Caregiver Abuse of Chicago Chinese Older Adults in a Community..
Pubmed ID:27606358 | PMC ID:PMC5008847
The Relationship of Older Adults' Physical Pain to Depression and..
Pubmed ID:27642644 | PMC ID:PMC5023019
Sphingosine 1-Phosphate Receptor 2 Regulates the Migration,..
Pubmed ID:27275017 | PMC ID:PMC4888913
Mammary Epithelial Cell Lineage Analysis via the Lyon's Hypothesis..
Pubmed ID:27453956 | PMC ID:PMC4957014
Epigenetic Loss of MLH1 Expression in Normal Human Hematopoietic Stem Cell..
Pubmed ID:27570841 | PMC ID:PMC4996274
Long-Term Function, Pain and Medication Use Outcomes of Radiofrequency..
Pubmed ID:26005713 | PMC ID:PMC4440581
Caspase Cleaved Tau in Alzheimer's Disease: A Therapeutic Target..
Pubmed ID:25639474 | PMC ID:PMC4308811
Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?..
Pubmed ID:26550607 | PMC ID:PMC4634668
Differences in ME and CFS Symptomology in Patients with Normal and..
Pubmed ID:28713856 | PMC ID:PMC5510614
Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive..
Pubmed ID:26005715 | PMC ID:PMC4440485
A Derivative of Differentiation-Inducing Factor-3 Inhibits PAK1..
Pubmed ID:26688830 | PMC ID:PMC4682050
Overcoming Endocrine Resistance in Hormone-Receptor Positive Advanced..
Pubmed ID:26726315 | PMC ID:PMC4697745
Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate..
Pubmed ID:26878064 | PMC ID:PMC4751054
Electron Microscopic Analysis of Silicate and Calcium Particles..
Pubmed ID:27158665 | PMC ID:PMC4858188
Effects of chest physical therapy in patients with non-tuberculous mycobacteria
Pubmed ID:28804763 | PMC ID:PMC5552049
A Community-Based Exercise and Support Group Program Improves Quality..
Pubmed ID:26640827 | PMC ID:PMC4667740
Four Weeks of Balance Training Does Not Affect Ankle Joint Stiffness in Subjects..
Pubmed ID:27642647 | PMC ID:PMC5025258
Social Ecology and Diabetes Self-Management among Pacific Islanders..
Pubmed ID:28736764 | PMC ID:PMC4516390
Examining Characteristics of Hospitalizations in Heart Failure Patients: Results..
Pubmed ID:28736765 | PMC ID:PMC5517048

Featured Articles


Role of Oxidative Stress and Apoptosis in the Hepatic Toxicity Induced by Cerium Oxide Nanoparticles Following Intratracheal Instillation in Male Sprague-Dawley Rats

Siva K Nalabotu, Nandini DPK Manne, Madhukar B Kolli, Geeta Nandyala, Radha K Para, Kevin M Rice, Cynthia B Jones and Eric R Blough

DOI: 10.23937/2572-4061.1510026



Hyponatremia in Children with Systemic Inflammatory Response Syndrome Presenting to the Emergency Department

Osama El-Assal, MD, PhD1, Sarah A Marzec, MD, Michael L Forbes, MD, Michael Bigham, MD, Ryan Reichert, MD, Jeffrey D Solomon, MD and Miraides F Brown, MS

DOI: 10.23937/2474-3674/1510085



Five Fruit and Vegetable a Day Does Not Reflect the Upward Trend of Obesity in the U.S.

Yilin Yoshida, Chester L Schmaltz, Jeannette Jackson-Thompson, Adam Bouras, Esmaeel Rahmani and Eduardo J Simoes

DOI: 10.23937/2572-3278.1510038


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin