ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

4
1
9
5

Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2469-5769/1510056

Intervention for Non-verbal and Minimally-Verbal Individuals with Autism: A Systematic Review

Lynn Kern Koegel, PhD, Katherine M Bryan, BA, Pumpki Su, MA, Mohini Vaidya and Stephen Camarata, PhD

Article Type: Review Article | First Published: September 27, 2019

Most children diagnosed with ASD will present with late onset verbal communication, and at least one third of these children will remain minimally or completely nonverbal throughout their lifespan, speaking few or no words. Challenges with verbal language can negatively affect many areas, including socialization, academics, independent living and employment. The objective of this paper was to systematically review interventions for the treatment of nonverbal and minimally verbal individuals with ASD. This review exclusively selected studies that targeted verbal communication in minimally and n...

 Open Access DOI:10.23937/2469-5807/1510102

Mathematical Hegselmann-Krause (HK) Model Predicts Chemotherapeutic Resistance to Cisplatin in Human Cervical Cancer Cell Lines

John Zihou Chen, Rong Wu, Henry Simpkins, Zhendong Sun and Jianli Chen

Article Type: Original Research Article | First Published: September 25, 2019

Solid tumors usually have a complex cellular components and intercellular interactions in a complex tumor microenvironment. We used a mathematical HK model to predict the change of drug resistance to cisplatin in a mixed sensitive and resistant human cervical cancer cell population and then employed a cytosensitivity assay to evaluate if biological findings could confirm this change predicted by HK model. We used the HK model to predict the resistance to cisplatin in the mixed cell population. To confirm this prediction, we mixed the sensitive and resistant cancer cells and studied their resis...

 Open Access DOI:10.23937/2469-5807/1510101

A Mathematical Method to Easily and Accurately Measure the Tumor Volume of Prostate Cancer on Pathological Slides

John Zihou Chen, Monika Wrzolek, Lynne Opitz and Jianli Chen

Article Type: Original Research Article | First Published: September 21, 2019

For decades, it has been a big challenge to directly and accurately measure an irregularly shaped area for a tumor volume evaluation of prostate cancer. All current methods are not ideal for different reasons. An objective, practical, accurate, and reliable method for measuring of prostate cancer volume is needed, in particular in modern precision medicine setting, pursuing accuracy and quality of health care. In this study, we applied a mathematical method - the Gauss area calculation formula to the evaluation of irregular shape of prostate cancer areas on H&E slides. To simplify the calculat...

 Open Access DOI:10.23937/2378-3001/1410091

Neuromodulation for Drug-Refractory Epilepsy and Chronic Heart Failure: Targets, Delivery, Composition and Titration

Inder S Anand, MD, FRCP, DPhil (Oxon), Marvin A Konstam, MD, Jeffrey L Ardel, PhD3, Imad Libbus, PhD, Lorenzo A DiCarlo, MD and Douglas L Mann, MD

Article Type: Original Articl e | First Published: September 23, 2019

Vagus nerve stimulation (VNS) is used currently in the management of drug-refractory epilepsy (DRE), and is in development for treating chronic heart failure (HF). HF is accompanied by autonomic nervous system (ANS) dysfunction, consisting of sustained sympathetic hyper-activation and withdrawal of parasympathetic tone, and associated with progressive worsening of cardiovascular (CV) function and increased morbidity and m ortality. We sought to compare how VNS is utilized for DRE and may potentially be employed for HF. Neuromodulation for the treatment of epilepsy and HF is not a one-size-fits...

 Open Access DOI:10.23937/2377-3634/1410112

Diabetes in Latin America: Prevalence, Complications, and Socio- Economic Impact

L Sinisterra-Loaiza, A Cardelle-Cobas, AG Abraham, MN Calderon, MA Espinoza, LG Gonzalez- Olivares, M Gotteland, A Pazos-Sierra, S San Martin, A Cepeda, JJ Gagliardino and IBEROBDIA Project Group

Article Type: Research Article | First Published: September 28, 2019

To review and update epidemiological data on type 2 diabetes (T2D) in Spain and four Latin American countries: Colombia, Mexico, Chile, and Argentina. Literature was reviewed by a search of PubMed, publications of the Ministry of Health, World Health Organization, International Diabetes Federation, and other public health agencies of each respective country. Of the five countries above, Mexico (13.6%) had the highest prevalence of diabetes, followed by Spain (10.4%). Within these countries, significant differences between urban and rural areas were observed (7.8% and 1.4%, respectively). Diabe...

 Open Access DOI:10.23937/2378-3419/1410125

The Role of Human Papillomavirus in Cervical Cancer

Beata Smolarz, Dariusz Samulak, Marianna Makowska, Hanna Romanowicz, Zbigniew Kojs, Luiza Wojcik and Magdalena M Michalska

Article Type: Review Article | First Published: September 28, 2019

Long-term infection with human papillomavirus (HPV) is the cause of cervical cancer and its precursor - cervical intraepithelial neoplasia (CIN). The presence of HPV infection can be presumed in more than 99% of cases of cervical cancer worldwide. The introduction of DNA testing for the presence of HPV has increased the effectiveness of screening programs for the detection of this cancer. This article contains the latest reports on the structure, function and role of HPV in the development of cervical cancer. It was also underlined the importance of performing molecular tests for the presence ...

 Open Access DOI:10.23937/2378-2951/1410159

Association between Platelet/Lymphocyte Ratio and Angiographic No-Reflow in Patients with None-St Segment Elevation Acute Myocardial Infarction Undergoing Primary Coronary Intervention

Ramazan Asoglu, Abdulmecit Afsin, Emin Asoglu3 and Arif Suner

Article Type: Research Article | First Published: September 26, 2019

Inflammation and platelet activation play a central role in the initiation and progression of the atherosclerosis process. The Platelet-to-lymphocyte ratio (PLR) is a new prognostic marker in coronary artery disease. The PLR is a significant independent predictor of longterm mortality after none-ST elevated myocardial infarction (NSTEMI). We aimed to evaluate the relationship between PLR and no-reflow (NR) in patients with NSTEMI. The present study included 173 patients with NSTEMI. The patients were classified into two groups as follows: 115 patients in the NR group and 58 patients in the nor...

 Open Access DOI:10.23937/2643-4512/1710028

Social Influences of Teachers, Classmates, and Parents on Children's Commitment to Physical Education and Language Education

Derwin KC Chan, Karen CH Lo and Felix Cheung

Article Type: Research Article | First Published: September 30, 2019

This study aims to examine the social influences of teachers, classmates and parents (i.e., positive reinforcement and punishment) on childrens commitment to physical education (PE) and language education (LE). Children from the UK (N = 614; Mean age = 13.05, SD = 2.01) completed the Perceived Social Influence Scale (Chan, et al. 2012), and also measures of competence, enjoyment, and effort in either the PE or LE context. Multi-group structural equation modelling (CFI = 0.97-0.98; TLI = 0.96-0.97; RMSEA = 0.03-0.04) showed that social influences from teachers, classmates, and parents explained...

 Open Access DOI:10.23937/2469-5823/1510134

Working through Others - A Qualitative Content Analysis of Nursing Students’ Experiences with Malnutrition at One Hospital in Vietnam

Elin Eriksson, RN, BSc, Victoria Ferm, RN, BSc and Kristina Rosengren, PhD, RN

Article Type: Original Article | First Published: October 05, 2019

Malnutrition causes problems in Vietnam, including illnesses with physiological and psychological complications. The aim of this study was to describe nursing students experiences with malnutrition at one hospital in Vietnam. Interviews of eight nursing students were performed, and the results were analysed by qualitative content analysis. This study highlights the use of guidelines in collaboration (between staff and patients’ relatives) to facilitate early identification and/or prevent malnutrition by improving self-care, as supported through nursing activities using family-centred care as...

 Open Access DOI:10.23937/2643-3966/1710023

Saphenous Vein Graft Aneurysm and Coronary Artery Disease: Case Report

Victor Rodrigues Ribeiro Ferreira, Maria Christiane Valeria Braga Braile-Sternieri, Eliana Migliorini Mustafa, Giovanni Braile Sternieri, Sofia Braile Sabino, Cibele Olegário Vianna Queiroz, Bethina Canaroli Sbardellini, Luiza Braile Verdi, Idiberto José Zotarelli Filho and Domingo Marcolino Braile

Article Type: Case Report | First Published: September 28, 2019

Despite a general reduction in the number of myocardial revascularization surgeries in recent decades, more than 150,000 are still performed annually in the United States. Early complications of venous graft use include an occlusion rate of up to 25% in the first year. The aneurysmal dilatation of the great saphenous vein, when used in aorto- coronary venous bridges, is rare and requires important care by the cardiology team. This study aimed to present a case report on saphenous vein aneurysm in a patient with coronary artery disease and myocardial ischemia who was diagnosed by angiotomograph...

Why ClinMed?

Preservation of author's rights
Global followership
Noncommercial objectives
Neutral and unbiased publishing process
Reprints issued accross the world
Timely submission for indexing
Published with CrossMark® policy

Editors' Picks

Can Genetic Testing Provide Information to Develop Customized Nutrigenomic..
Pubmed ID:26225358 | PMC ID:PMC4516390
Acute Ovarian Insufficiency and Uterine Infarction Following Uterine Artery..
Pubmed ID:26523290 | PMC ID:PMC4623578
Challenges of Fertility Sparing Ovarian Surgery Imposed by Krukenberg..
Pubmed ID:26366440 | PMC ID:PMC4563814
Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral..
Pubmed ID:27398405 | PMC ID:PMC4936830
Hypothesizing that a Pro-Dopaminergic Regulator (KB220z™ Liquid Variant)..
Pubmed ID:29034323 | PMC ID:PMC5638455
Titanates and Titanate-Metal Compounds in Biological Contexts..
Pubmed ID:26430701 | PMC ID:PMC4587770
MyHEART: A Non Randomized Feasibility Study of a Young Adult..
Pubmed ID:28191544 | PMC ID:PMC5300088
Exenatide Effects on Cardiometabolic Risk and Weight in Adolescents..
Pubmed ID:27182560 | PMC ID:PMC4864000
A New Animal Model to Study Endogenous Cardiotonic Steroids and the Progression..
Pubmed ID:26457335 | PMC ID:PMC4599712
Common Genetic Variation in Circadian Rhythm Genes and Risk of..
Pubmed ID:26807442 | PMC ID:PMC4722961
Active Hexose Correlated Compound Activates Immune Function to Decrease..
Pubmed ID:27790645 | PMC ID:PMC5079436
The Extraction, Anticancer Effect, Bioavailability, and..
Pubmed ID:27790646 | PMC ID:PMC5079443
Kyphosis and Sleep Characteristics in Older Persons: The Rancho..
Pubmed ID:28480455 | PMC ID:PMC5419044
Suppression of Experimental Arthritis through AMP-Activated Protein..
Pubmed ID:26120598 | PMC ID:PMC4479345
Aspirin-Triggered Resolvin D1 Versus Dexamethasone in the Treatment of..
Pubmed ID:27110599 | PMC ID:PMC4841619
Elder Mistreatment and its Subtypes across Different Sociodemographic and..
Pubmed ID:26973979 | PMC ID:PMC4786076
Balance and its Clinical Assessment in Older Adults - A Review..
Pubmed ID:26942231 | PMC ID:PMC4773046
Caregiver Abuse of Chicago Chinese Older Adults in a Community..
Pubmed ID:27606358 | PMC ID:PMC5008847
The Relationship of Older Adults' Physical Pain to Depression and..
Pubmed ID:27642644 | PMC ID:PMC5023019
Sphingosine 1-Phosphate Receptor 2 Regulates the Migration,..
Pubmed ID:27275017 | PMC ID:PMC4888913
Mammary Epithelial Cell Lineage Analysis via the Lyon's Hypothesis..
Pubmed ID:27453956 | PMC ID:PMC4957014
Epigenetic Loss of MLH1 Expression in Normal Human Hematopoietic Stem Cell..
Pubmed ID:27570841 | PMC ID:PMC4996274
Long-Term Function, Pain and Medication Use Outcomes of Radiofrequency..
Pubmed ID:26005713 | PMC ID:PMC4440581
Caspase Cleaved Tau in Alzheimer's Disease: A Therapeutic Target..
Pubmed ID:25639474 | PMC ID:PMC4308811
Corpora Amylacea in Neurodegenerative Diseases: Cause or Effect?..
Pubmed ID:26550607 | PMC ID:PMC4634668
Differences in ME and CFS Symptomology in Patients with Normal and..
Pubmed ID:28713856 | PMC ID:PMC5510614
Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive..
Pubmed ID:26005715 | PMC ID:PMC4440485
A Derivative of Differentiation-Inducing Factor-3 Inhibits PAK1..
Pubmed ID:26688830 | PMC ID:PMC4682050
Overcoming Endocrine Resistance in Hormone-Receptor Positive Advanced..
Pubmed ID:26726315 | PMC ID:PMC4697745
Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate..
Pubmed ID:26878064 | PMC ID:PMC4751054
Electron Microscopic Analysis of Silicate and Calcium Particles..
Pubmed ID:27158665 | PMC ID:PMC4858188
Effects of chest physical therapy in patients with non-tuberculous mycobacteria
Pubmed ID:28804763 | PMC ID:PMC5552049
A Community-Based Exercise and Support Group Program Improves Quality..
Pubmed ID:26640827 | PMC ID:PMC4667740
Four Weeks of Balance Training Does Not Affect Ankle Joint Stiffness in Subjects..
Pubmed ID:27642647 | PMC ID:PMC5025258
Social Ecology and Diabetes Self-Management among Pacific Islanders..
Pubmed ID:28736764 | PMC ID:PMC4516390
Examining Characteristics of Hospitalizations in Heart Failure Patients: Results..
Pubmed ID:28736765 | PMC ID:PMC5517048

Featured Articles


Role of Oxidative Stress and Apoptosis in the Hepatic Toxicity Induced by Cerium Oxide Nanoparticles Following Intratracheal Instillation in Male Sprague-Dawley Rats

Siva K Nalabotu, Nandini DPK Manne, Madhukar B Kolli, Geeta Nandyala, Radha K Para, Kevin M Rice, Cynthia B Jones and Eric R Blough

DOI: 10.23937/2572-4061.1510026



Hyponatremia in Children with Systemic Inflammatory Response Syndrome Presenting to the Emergency Department

Osama El-Assal, MD, PhD1, Sarah A Marzec, MD, Michael L Forbes, MD, Michael Bigham, MD, Ryan Reichert, MD, Jeffrey D Solomon, MD and Miraides F Brown, MS

DOI: 10.23937/2474-3674/1510085



Five Fruit and Vegetable a Day Does Not Reflect the Upward Trend of Obesity in the U.S.

Yilin Yoshida, Chester L Schmaltz, Jeannette Jackson-Thompson, Adam Bouras, Esmaeel Rahmani and Eduardo J Simoes

DOI: 10.23937/2572-3278.1510038


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin