Prevalence of Diabetes Mellitus in Outpatients with Essential Hypertension in a Rural Tertiary Hospital
Ogunmola Olarinde Jeffrey, Ajani Gbadebo Oladimeji and Olabinri Eunice Oluremi
Article Type: Original Article | First Published: December 16, 2019
To determine the prevalence of diabetes mellitus (DM) in patients with essential hypertension attending outpatient medical clinic in a rural community setting of a developing country. This cross-sectional study included patients of a medical outpatient clinic in Federal Teaching Hospital Ido Ekiti, Ekiti State, Nigeria. Study patients were consecutively recruited from Cardiac clinic and baseline investigations obtained from the patients’ files were evaluated including Fasting Blood Glucose (FBG).The estimated minimum sample size was 80 with probability of type 1 error, assumption of α = 0.0...
A Signal Detection Analysis of World Health Organization’s Pharmacovigilance Database
Article Type: Original Article | First Published: December 14, 2019
Pharmacovigilance is the primary method used to identify hazards associated with medicinal products. Using generalized likelihood ratio tests, we examed the adverse reaction signals of the drug class Monoamine oxidase inhibitors (MAOIs) from World Health Organization’s Pharmacovigilance Database. The proposed test procedure has the ability of detecting adverse reactions of multiple drugs simultaneously. Our findings sugggest there are 23 common Adverse reaction signals detected within this drug class. And postural hypotension, high blood pressure, fainting, abnormal heart rhythm, dizziness, ...
First Observation of Two TMPRSS6 Gene Mutations (G603R and K636AFSX17) in Turkish Population
Yasemin Ardicoglu Akisin, Gulnaz Kurt, Hüseyin Onay, Ferda Ozkinay and Nejat Akar
Article Type: Case Report | First Published: December 20, 2019
Iron is one of the elements that participate numerous reaction on the body and the structure of hemoglobin to the purpose of carrying oxygen to the tissues. Thus, iron deficiency causes different problems in the body. Iron-refractory iron deficiency anemia (IRIDA) is a genetic disorder that has some signs of iron deficiency anemia (IDA) but refractory to oral iron and partially refractory to intravenous iron. The mutation in TMPRSS6 gene causes matriptase-2 protein deficiency that negatively regulates hepcidin molecule. Thus, increasing hepcidin connects its receptor ferroportin and decreases ...
Perioperative Management of Multiple Intracranial Nail Gun Injuries
Matthew B Ellison, MD, Jeremy Hensley, MD, Roy E Henrickson, MD, Jeffrey Puette, MD, Jason Shepherd, MD, Daniel Sloyer, MD and Pavithra R Ellison, MD
Article Type: Case Rep ort | First Published: January 04, 2020
A 51-year-old male presented to the emergency department with four self-inflicted nail gun wounds. Computed tomography angiography demonstrated three nails penetrating the frontal bone toward the falx cerebri causing small subdural hematomas. The fourth nail penetrated the parietal bone posteriorly, ending very close to the vein of Galen. Despite the ominous-appearing imaging, the patient was neurologically intact and cooperative to the point that consideration was given to the possibility of removal of the nails under local anesthesia. Due to the number of nails and proximity of the fourth na...
Does Esmolol Havean Effect on Erythrocyte Deformability in Rat Lower Limb Ischemia Reperfusion Injury?
Ali Dogan Dursun, Faruk Metin Comu, Aysegul Kucuk, Ulku Sabuncu, Nevriye Salman, Timucin Sabuncu, Gulay Kip, Omer Kurtipek and Mustafa Arslan
Article Type: Original Article | First Published: December 20, 2019
Ischemia reperfusion (I/R) injury is a common problem in vascular surgery. We aimed to investigate the effects of esmolol on erythrocyte deformability in rat lower limb I/R injury. Following Ethics Commitee approval 24 rats were randomly divided into 4 groups, Control (Group C), Esmolol (Group E), Ischemia-reperfusion (Group I/R), I/R-Esmolol (Group I/R-E). In I/R group, atraumatic microvascular clamp was placed to infrarenal abdominal aorta. After 120 minutes from ischemia, the clamp was removed and reperfusion was performed for 120 minutes. Esmolol (200 μg/kg/min) was administered 30 minute...
Effect, Adverse Events and Re-operations after Tension-free Vaginal Tape Obturator Surgery
Silja Maigaard Axelsen, Rikke Guldberg Sorensen, MD, PhD and Susanne Axelsen, MD, PhD
Article Type: Original Article | First Published: December 18, 2019
Women with stress urinary incontinence can be offered an operation with mid-urethral sling. First, Tension- free vaginal tape was invented. Some years later, because of concerns about complications associated with this operation, the other minimally invasive procedure using the trans obturator procedure was introduced by Dr. J. de Leval in 2003. Since then, the diversity in methods gave rise to a discussion of both efficacy, complications and reoperations. In Denmark, the professional discussion about Tension-free Vaginal Tape Obturator is ongoing, which is an important reason for evaluating t...
Nursing Students' Views and Experiences Concerning the Use of Mobile Applications in Nursing Education: A Qualitative Study
Ayse Kacaroglu Vicdan and Media Subasi Baybuga
Article Type: Original Article | First Published: December 19, 2019
Nursing education is a process of education that consists of both theoretical and skill teaching. Mobile applications developed in accordance with smart phones have started to be used in nursing education, for the stu-dents to continue to learn outside school and develop their knowledge and skills. This study was conducted in the Department of Nursing in the Faculty of Health Sciences at a University located in the western region of Turkey between the dates of between May 7, 2019, and May 30, 2019, by using quali-tative research design. Qualitative research...
Tuberculosis Re-Treatment Cases and Factors Associated with Unfavourable Outcome at the Fann University Hospital of Dakar, Senegal between 2011 and 2016: A Follow-Up Study
Viviane Marie Pierre Cisse Diallo, Louise Fortes Deguenonvo, Aminata Massaly, Ndeye Aissatou Lakhe, Daye Ka, Khardiata Diallo M Baye, Ndeye Fatou Ngom Gueye, Assane Diouf, Farah Djamal Waberi, Alassane Dieye, Ndeye Maguette Fall, Cheikh Tacko Diop, Cheikh Tidiane Ndour, Sylvie Diop Nyafouna, Masserigne Soumare and Moussa Seydi
Article Type: Research Article | First Published: December 09, 2019
The aim of our study was to describe the socio-demographic, clinical, therapeutic and evolutionary characteristics of patients admitted to tuberculosis re-treatment and managed at the The Infectious and Tropical Diseases Department (SMIT) screening and tuberculosis treatment center (TTC), to determine the factors associated with unfavourable outcome. This is a descriptive and analytical retrospective cross sectional study covering all tuberculosis re-treatment cases monitored in the service of infectious and tropical diseases in Fann from 1 January 2011 to 31 December 2016. The Epi-Info softwa...
Histopathologic Detection and Identification of Infectious Agents in Granulomatous Inflammation: Comparison with Culture
Sarah Hackman, MD and Daniel D Mais, MD
Article Type: Original Article | First Published: December 09, 2019
Granulomas in surgical specimens, especially within lung and lymph nodes, commonly have an infectious etiology. Granulomatous tissue is usually sent to both surgical pathology for tissue examination and to clinical microbiology laboratories for culture. We performed a retrospective review and comparison of histochemical stains and clinical microbiology culture results in 132 surgical pathology granuloma specimens to determine the utility of tissue morphological examination for detection and identification of fungi and acid-fast bacilli as compared to clinical microbiology culture....