Some Aspect of Clinical Assessment of Carpal Unstability and Colapsus in Untreated Rheumatoid Arthritis
Article Type: Research Article | First Published: September 08, 2015
The carpal instability is a biomechanical alteration with multiple pathogenesis. It ensues due to disturbance of the normal ligament and bone connections that control the wrist. There are four major types of carpal instability: 1 Dorsal Intercalated Segment Instability (DISI) 2.Volar Intercalated Segment Instability (VISI) 3.Ulnar translocation, and 4. Medial carpal instability. Instability in the wrist in Rheumatoid Arthritis (RA) appears as a result of incongruity between joint and bone surfaces, capsular and ligament laxity and muscle-tendon imbalance....
Heart Transplant for Dextrocardia Situs Inversus with Very Complex Congenital Lesion: a Challenge of Cardiac Surgery
Nguyen Huu Uoc and Pham Tien Quan
Article Type: Research Article | First Published: September 14, 2015
27 year-old female patient had complex CHD that involved dextrocardia situs inversus, double outlet right ventricle type TGA, pulmonary artery stenosis, total atrio-ventricular canal, and total anomalous pulmonary venous connection type supra-cardia. She was experiencing end-stage heart failure and severely cachexia with risk of death within few months. The transplanted heart was from a multi-organ donor; male, 26 years old, normal heart structure. Although the difference in biological parameters between donor and recipient were with in acceptable limits, most of the steps in an otherwise norm...
Arrhythmic Manifestation of Prinzmetal' Sangina Induced by Therapeutic Hypothermia
Abellas-Sequeiros RA, Ocaranza-Sanchez R, Garcia-Acuna JM and Gonzalez-Juanatey JR
Article Type: Case Report | First Published: September 03, 2015
We report the case of a 37-year-old Caucasian man, with prior history of smoking and DM. He had complained about multiple episodes of syncope during last year. However, the day of his hospitalization, he described a sudden and acute episode of chest pain which stopped him from sleeping. He arrived to the emergency department after 45 minutes of successful resuscitation, with VF as first cardiac rhythm detected....
Guidewire Fracture during Crossing A Chronic Coronary Total Occlusion: A Troublesome Experience
ErsanTatli, MustafaYilmaztepe, Ali Buturak and Yusuf Can
Article Type: Case Report | First Published: August 30, 2015
Increased interest focusing on coronary chronic total occlusions has emerged since several studies have proven improved cardiovascular outcomes and quality of life after successful chronic total occlusion (CTO) revascularization. CTO of an epicardial coronary artery is one of the leading challenging complex lesion type when percutaneous coronary intervention (PCI) is indicated. Advanced antegrade and retrograde techniques performed with dedicated equipment have provided significant improvements in procedural success and decrease periprocedural complications leading to PCI failure....
Overview of Coroner's Adult Autopsies in England
Husayn Al Mahdy
Article Type: Review Article | First Published: September 11, 2015
This article provides an overview of coroner's autopsies in England with the aim of improving the service and hence provide accurate death certification as well as a learning experience for clinicians caring for patients. The system that has evolved has neither improved the service nor has it led to a learning experience for the clinicians. Compatibility of clinical features ante-mortem combined with post-mortem findings are lacking and involvement of the clinicians is almost non-existent. The coroner's pathologists invariably works in isolation and the clinicians do not get any opportunity to...
Factors Predicting Response to Neoadjuvant Therapy of Hepatic Metastasis from Colorectal Carcinoma
D. Cortes Guira,, MJ Fernandez-Acenero, Damian Garcia-Olmo and C. Pastor Idoate
Article Type: Review Article | First Published: September 03, 2015
Neoadjuvant chemotherapy (NAC) is a widely used therapeutic option for patients with resectable hepatic metastasis from colorectal carcinoma. In this setting, the intent of NAC is to reduce metastatic size and make surgery easier and/or less extensive, mostly in patients that are amenable to surgery. Several studies confirm that response to neoadjuvant therapy is indicative of a better prognosis for such patients and several methods have been proposed and validated to measure both radiological and histopathological response. However, surgery remains the only curative option for these patients ...
Ovarian Neoplasm in a Patient with Prior Breast Carcinoma - Challenges and Pitfalls in Diagnostic Process
Elena Arabadzhieva, Sasho Bonev, Lyubomira Dimitrova, Atanas Yonkov, Dimitar Bulanov, Vesela Ivanova and Violeta Dimitrova
Article Type: Case Report | First Published: September 02, 2015
We present a case of 58-year-old woman who underwent bilateral adnexectomy with small bowel resection during urgent operation for an incarcerated umbilical hernia. There was a slight enlargement in both ovaries and presence of cystic formation with some papillary structures in the right one. Histologically, bilateral infiltration of tumor cells with moderate cytological and nuclear atypia and tubular, nested and cystic growth pattern was observed. The patient had a long list of co-morbidities: liver cirrhosis, ascites, isolated cytology with presence of tumor cells, elevated level of CA-125 an...
The Optimization of Igm In-House ELISA for the Laboratory Diagnosis of Melioidosis in Malaysia
Azura Mohd Noor, Norazah Ahmad and Wan Rozita Wan Mahiyuddin
Article Type: Research Article | First Published: September 02, 2015
Melioidosis is a life-threatening infectious disease which can lead to high mortality and death within 48 hours if treatment is delayed. Detection of antibodies against Burkholderia pseudomallei may help in early diagnosis of melioidosis. This study was carried out to optimize an in-house ELISA for the detection of Immunoglobulin M (IgM) against B. pseudomallei in suspected acute melioidosis patients in Malaysia. Three different concentrations of crude B. pseudomallei cells antigen (0.200 mg/ml, 0.100 mg/ml and 0.05 mg/ml) and 2 different dilutions of conjugate (1:2000 and 1:4000) were used. T...
Sleep Characteristics in Blind Subjects
Fructuoso Ayala-Guerrero and Graciela Mexicano
Article Type: Research Article | First Published: September 14, 2015
The sleep patterns of ten blind adults and their matched controls were studied during three consecutive nights. The first night was allowed for adaptation. Significant electroencephalographic and quantitative findings were obtained from nights 2 and 3. Although alpha-like rhythm was registered in only one blind subject during wakefulness, it was displayed by 8 of the 10 blind participants of this study during REM sleep. This rhythm was also present during the N2 sleep stage. The delta phase of sleep was markedly reduced as compared to the healthy subjects....