Long-Term Survival and Quality of Life Outcomes with Multiple Gamma Knife Radiosurgeries for Metastatic Breast Cancer to the Brain: Case Report and Review of Literature
Andrew T Roehrig, Ethan Ferrel, Robert K Fairbanks, Wayne T Lamoreaux, Alexander R MacKay, Jason A Call, John J Demakas, Aaron Wagner, Barton S Cooke, Benjamin C. Ling, Jonathan D. Carlson and Christopher M Lee
Article Type: Case Report | First Published: December 14, 2015
Metastatic disease to the brain from breast cancer can be treated with multiple modalities. Determining effective therapies for select patients with brain metastases is critical to maximizing survival and quality of life. Stereotactic radiosurgery (SRS) can be an effective option for select patients with brain metastases, and is highly targeted with rapid fall-off of radiation dose outside the treatment zone. The following case illustrates the potential use of multiple Gamma Knife Radiosurgery (GKRS) sessions for a patient with metastatic breast cancer. In this specific case, repeat treatments...
Patient Reported Outcome in a New Home-Based Rehabilitation Programme for Prostate Cancer Patients
Brigitta R Villumsen and Britta Hordam
Article Type: Research Article | First Published: December 26, 2015
The most optimal and individual exercise plan for men with prostate cancer receiving androgen deprivation therapy needs to be identified. We plan to investigate in these patients the effect of a 12-week home-based exercise programme on physical function, fatigue and metabolic parameters. We will also investigate the satisfaction and experience with the exercise tool. To the best of our knowledge this is the first study to investigate the effect of an interactive video gaming console on a home-based exercise programme. No statistical analysis have been made so far because inclusion is still ong...
An Integrative Review of Sickle Cell and Depression
Kimberly L. Tartt, Susan J. Appel, Valerie Mann-Jiles, Kahlil Demonbreun and John Langlow III
Article Type: Review Article | First Published: December 16, 2015
Purpose:Gain insight and knowledge through the exploration of depression among adult patients living with chronic illness such as sickle cell disease. The review focused on defining the prevalence of depression in chronic illness with emphasis on sickle cell. Associated chronic pain, quality of life, disease trajectory and the need for increased screening and treatment for depression in chronic illness such as with those living with sickle cell disease will be evaluated. Data Sources:A search of the following databases: Cumulative Index to Nursing and Allied Health Literature, Cochrane Library...
Intravitreal Implant of Dexamethasone for Treatment of Refractory Cystoid Macular Edema Surgically Induced After Pars Plana Vitrectomy
Rino Frisina and Barbara Parolini
Article Type: Research Article | First Published: November 02, 2015
Purpose: To evaluate the efficacy and safety of intravitreal implant of Dexamethasone (Ozurdex, Allergan, Irvine, Calif, USA) for the treatment of refractory and chronic cystoid macular edema secondary to PPV and peeling of ERM and internal limiting membrane (ILM) with or without simultaneous cataract surgery. Methods: Seven eyes of 7 patients affected by chronic and refractory CME for at least 3 months after vitrectomy and peeling of ERM and ILM, were recruited. All patients underwent intravitreal injection of 0.7 mg of Dexamethasone (IVO injection). Demographic data, preoperative and postope...
The Cornea after Primary Blast Trauma
Denise S Ryan, Bennett J Oberg, Michael J Mines, Rose K Sia, Keith J Wroblewski, Marcus Colyer, Dal Chun, Eric Weichel and Kraig S Bower
Article Type: Research Article | First Published: October 16, 2015
Purpose: This study examined the seemingly uninjured eye of soldiers with blast injuries involving the head, face, and fellow eye to obtain insight into primary blast ocular injuries. Methods: Serial exams were performed on nineteen U.S. Army Soldiers with a combat-related blast injury involving the head, face and either eye for effects of primary blast trauma in the clinically unaffected eye. Outcome measures included corrected distance visual acuity (CDVA), endothelial cell density (ECD), corneal hysteresis (CH), corneal resistance factor (CRF), cornea compensated intraocular pressure (IOPcc...
Symptomatic Yuxta-articular Facet Cyst: A Case Report
J Miguel Rodriguez Solera, Ana M Cervan de la Haba, Miguel S Hirschfeld Leon and Enrique Guerado Parra
Article Type: Case Report | First Published: December 30, 2015
We report a case of 66 years-old male with left leg pain that began six months earlier. The pain was aggravated by sitting or climbing stairs but was relieved in the standing position. The physical examination was consistent with a left radiculopathy without sensory or motor deficit. His initial MRI lumbar spine demonstrated a cystic mass with T1 and T2 hyperintensity on the L3-L4 level with considerable thecal sac and nerve root compression. The lesion originated next to the left L3-4 facet joint and extended centrally under the lamina of L3 and L4. A surgical treatment was offered to the pat...
Fracture-Dislocation of the Upper Thoracic Spine without Neurologic Associated Injury: Two Cases Report
J Miguel Rodriguez Solera, Ana Maria Cervan de la Haba, Miguel S Hirschfeld Leon and Enrique Guerado Parra
Article Type: Case Report | First Published: December 22, 2015
We report a case of 51 years-old male with no past medical history, who was brought to our Hospital after falling from a 10 meters high roof. He had 15 points at Glasgow Coma Scale (GCS) and a completely normal neurological examination. A whole body computerized tomography (CT) scan was performed and diagnosed a fracture-dislocation at T8-T9. Acute surgery was decided, performing an open reduction and internal fixation with pedicle screws from T6 to T1. Clinical outcome was favorable....
Investigation of Intraventricular Hemorrhage Volume in Motor Vehicle Crash Occupants
Jillian E Urban, Christopher T Whitlow and Joel D Stitzel
Article Type: Original Article | First Published: December 17, 2015
Motor Vehicle Crashes (MVCs) are a leading cause of traumatic intracranial injuries which often have devastating impacts on morbidity and mortality. Intraventricular hemorrhage (IVH) is one type of head injury that is identified on post-traumatic computed tomography (CT) scans. IVH is observed less frequently in patients with head trauma, however it is often associated with severe head trauma and negative prognostic outcomes and causation of traumatic IVH is not well-understood. The severities of injuries are often quantified by geometric and volumetric measurements. Studying the relationship ...
Fracture of the Femoral Neck: SOIB Method
Rinaldo Giancola, Lorenzo Marchesi and Guido Antonini
Article Type: Case Report | First Published: December 14, 2015
Treating fractures of the proximal femur remains a controversial problem. Fractures of the femoral neck occur almost exclusively amongst the elderly (fractures due to bone frailty associated with osteoporosis), whereas fractures in younger people are due to high-energy trauma. The current treatment trend in clinical practice and the literature for these fractures is prosthetic replacement. In this article the authors describe the case of an 81-year-old woman who underwent osteosynthesis due to a left subcapital fracture (Garden II) using the SOIB method. The operation consisted in stabilising ...