ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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 Open Access DOI:10.23937/2474-1353/1510009

Osteitis Pubis in a 30 Year Old Postpartum Recreational Runner: A Case Report

Dani Moffit, Tim Braun and Kurt Schiess

Article Type: Case Report | First Published: December 31, 2015

A 30-year old female recreational runner presented groin, hip adductors, rectus abdominis, and inguinal ligament pain. Previous history revealed the pain started three years prior, recently increasing with activities of daily living. After birth of her third child, pain increased so she could not perform daily tasks such as grocery shopping, and was unable to hold her children. Examination revealed normal gait, level iliac crests, and normal lumbar curve. Palpation revealed tenderness over her right adductors and in medial thigh near the pudendal region. Differential diagnoses included hip add...

 Open Access DOI:10.23937/2474-1353/1510008

Using Intervention Mapping for Systematic Development of a Midwife-Delivered Intervention for Prevention and Reduction of Maternal Distress during Pregnancy

Yvonne Fontein-Kuipers, Evelien van Limbeek, Marlein Ausems, Raymond de Vries and Marianne Nieuwenhuijze

Article Type: Original Article | First Published: December 22, 2015

Maternal distress is a major concern for perinatal health. We define maternal distress as a spectrum consisting of a variety of psychological constructs that occur during the antenatal period. Maternal distress can be the result of pregnancy or birth or other non-pregnancy related experiences in a woman's past or present life. It varies in severity from stress, worry, and concerns to more serious feelings of unhappiness, anxiety and/or depression and disturbed psychological functioning. Maternal distress has shown to have adverse consequences for women, children, including obstetric complicati...

 Open Access DOI:10.23937/2474-1353/1510007

A Mixed-Methods Evaluation of Potential Distribution Channels for the V Condom in South Africa

Jenni Smit, Nzwakie Mosery, Lavanya Pillay, Mags Beksinska, Letitia Rambally-Greener, Cecilia Milford, Maggie Kilbourne-Brook and Patricia S. Coffey

Article Type: Original Article | First Published: December 22, 2015

Increasing access to underutilized family planning methods is of global concern. The United Nations Commission on Life-Saving Commodities identified the female condom (FC) as one of 13 essential and overlooked commodities. Male and female condoms are currently the only effective method of dual protection against unintended pregnancy and the transmission of sexually transmitted infections (STIs) including human immunodeficiency virus (HIV). A new design of female condom with special features to make it easy to use and acceptable to both women and men, the V Condom, has been evaluated in clinica...

 Open Access DOI:10.23937/2378-346X/1410044

Lutein and Zeaxanthin Isomers Inhibits Cholinesterase and Modulates the Expression of Inflammation-Related Genes: In Vitro Models

Khadija Ghanam, Jayant Deshpande and Vijaya Juturu

Article Type: Research Article | First Published: December 16, 2015

It is well established that ultraviolet (UV) radiation induces immunomodulatory effects involved in different chronic conditions including skin cancer, age-related macular degeneration (AMD), refractive errors, glaucoma and cataracts. Epidemiological studies suggest solar radiation is responsible for some of the deteriorating changes that lead to AMD Recent studies have shown that UVA (320-400 nm) and UVB (290-320 nm) radiation are immunosuppressive. Experimental studies have demonstrated that bright light preferentially damages precisely the region that degenerates in AMD. The retina is highl...

 Open Access DOI:10.23937/2378-346X/1410043

Clinical Evidence of Ambient Temperature Variations on Femtosecond Laser Performance and Comparison with a Mechanical Microkeratome

Bojan Pajic, Brigitte Pajic-Eggspuehler, Iraklis Vastardis, Michael Mrochen and Zeljka Cvejic

Article Type: Research Article | First Published: December 15, 2015

The mechanism of flap creation with the IntraLase femtosecond laser has already been described extensively in the literature over the years. Femtosecond laser systems produce energy pulses (600 to 800 femtosecond) at an infrared wavelength of 1053 nm. The ultra-short impulses are focused at a spot size of a few micrometers in diameter at a preset depth within the stroma, leading to photo disruption and to a creation of a corneal resection plane. Once the flap has been created, the device creates a side cut at the level of the resection plane, moving anteriorly through the corneal stroma and ep...

 Open Access DOI:10.23937/2378-346X/1410042

New Diagnostic Criteria for Infantile Nystagmus. An Upgraded Nystagmus Clinical Approach

Nadim Nasser

Article Type: Original Article | First Published: November 26, 2015

Purpose: CEMAS group has classified nystagmus comprehensively in 2001. From that time, several attempts to make the subject as uniform as possible, needed continuous upgrading. This manuscript is an upgraded clinical approach for diagnosis of Irreversible Congenital Nystagmus, which is in addition to its being one of the major clinical features of intrinsic ocular diseases, is also a sign of inborn errors of myelination. Design: We will accompany the way to the diagnosis of congenital irreversible nystagmus of non-intrinsic eye disease origin, by highlighting all the symptoms and signs, which ...

 Open Access DOI:10.23937/2377-3634/1410047

Glucose Tolerance is Improved Following Surgery for Silent Somatotroph Adenoma

Aika Miya, Akinobu Nakamura, Hideaki Miyoshi, Hiraku Kameda, Hiroshi Nomoto, So Nagai, Yuko Omori, Kanako C. Hatanaka, Hiroyuki Kobayashi, Chikara Shimizu, and Tatsuya Atsumi

Article Type: Case Report | First Published: November 05, 2015

Although the excessive secretion of GH leads to insulin resistance enhancement, the involvement of a silent somatotroph adenoma in abnormal glucose tolerance has not been elucidated. A 50 - year-old man was admitted with a headache and bitemporal hemianopia caused by a pituitary macroadenoma. He had no physical signs and symptoms of acromegaly nor hypopituitarism, and his base-line serum levels of GH and insulin - like growth factor-1 (IGF-1) were normal. However, a 75 - g oral glucose tolerance test (OGTT) showed unsuppressed GH concentrations as well as plasma glucose levels consistent with ...

 Open Access DOI:10.23937/2377-3634/1410046

Why so Fat ?

Franco Contaldo, Maurizio Marra, Lidia Santarpia and Fabrizio Pasanisi

Article Type: Hypothesis | First Published: October 28, 2015

We selected, from our database of obese outpatients, 90 young severely obese subjects (60 females, 30 males) in a stable body weight since at least 6 months, age range 20 - 30 years, who underwent measurements of resting energy expenditure (REE) by indirect calorimetry (VMax Sensor Medics) and body composition was evaluated by bioelectrical impedance (BIA). Bio impedance analysis (BIA) was performed at 50 kHz (Human Im plus II, DS Medica) in standard conditions....

 Open Access DOI:10.23937/2378-3419/3/1/1038

Multimodal Treatment of Breast Cancer Liver Metastases Based on Hepatic Resection and Microwave Coagulo-Necrotic Therapy (MCN)

Yuko Takami, Susumu Eguchi, Masaki Tateishi, Tomoki Ryu, Kazuhiro Mikagi, Yoshiyuki Wada and Hideki Saitsu

Article Type: Original Article | First Published: January 11, 2016

Background: Generally it is rare to select surgery for treating breast cancer liver metastases (BCLM), but we have carried out aggressively surgical treatment to BCLM. Especially as a part of treatment strategies, we have used intraoperative loco-regional microwave ablation, named microwave coagulo-necrotic therapy (MCN). In this study, we investigate whether or not surgical treatment, combining hepatic resection and/or MCN, is useful for treating BCLM. Methods: Between 1994 and 2014, 33 patients with BCLM were surgically treated at National Hospital Organization Kyushu Medical Center by means...

 Open Access DOI:10.23937/2378-3419/3/1/1037

Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate Tumor Growth in the Mouse Ectopic Xenograft Model: A Zinc Approach for the Efficacious Treatment of Prostate Cancer

Renty B. Franklin, Jing Zou, Yao Zheng, Michael J. Naslund, Leslie C. Costello

Article Type: Research Article | First Published: January 09, 2016

Prostate cancer remains the second leading cause of cancer deaths in males. This is mainly due to the absence of an available efficacious chemotherapy despite decades of research in pursuit of effective treatment approaches. A plausible target for the treatment is the established clinical relationship that the zinc levels in the malignant cells are markedly decreased compared to the normal epithelium in virtually all cases of prostate cancer, and at all stages malignancy. The decrease in zinc results from the downregulation of the functional zinc uptake transporter, ZIP1; which occurs during e...

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