ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2469-5823/1510023

Combining Breastfeeding and Employment: The Salient Beliefs of Nurses Working Shift Work in a Hospital

Sarah Mestepey, Susan K. Steele-Moses and Annette Knobloch

Article Type: Research Article | First Published: December 28, 2015

Combining breastfeeding and employment has been a struggle for mothers for many years. Working mothers are pressed to find a balance between employment responsibilities and the duties of motherhood. Until recent legislation, the Patient Protection and Affordable Care Act of 2010, there were essentially no federal regulations to protect a woman's breastfeeding rights; even the latest legislation is far from inclusive toward the protection of a woman's liberty to maintain lactation once she returns to work....

 Open Access DOI:10.23937/2469-5734/1510020

Prevalence of Taurodontism in Mandibular Molars among Patients at a Dental Care Institution in Nigeria

Yemitan Tolulase Abosede and Adediran Virginia Efunyemi

Article Type: Original Research Article | First Published: November 18, 2015

Taurodontism involves enlargement of the body of the tooth and shortening of the roots. This anomaly could be an isolated trait, or could be in association with other anomalies or may be a component of a syndrome. This study aims to determine the prevalence of taurodontism in mandibular molars of a Nigerian sample. The objectives are to test the hypotheses that there is no gender preference in taurodontism, and that there is no preference for either left or right side of the mandible....

 Open Access DOI:10.23937/2469-570X/1410014

Sphingosine 1-Phosphate Receptor 2 Regulates the Migration, Proliferation, and Differentiation of Mesenchymal Stem Cells

S Tucker Price, Thomas H Beckham, Joseph C Cheng, Ping Lu, Xiang Liu and James S Norris

Article Type: Research Article | First Published: December 02, 2015

Mesenchymal stem cells (MSCs) are a multipotent cell population acquired most prominently from bone marrow with the capacity to differentiate into osteoblasts, chondrocytes, adipocytes, and others. MSCs demonstrate the capacity to home to sites of injury and contribute to tissue repair. Sphingosine 1-phosphate (S1P) is a biologically active sphingolipid impacting proliferation, apoptosis, inflammation, and angiogenesis with changes in S1P concentration providing significant implications for various disease conditions including cancer, diabetes, and cardiac disease. These functions are primaril...

 Open Access DOI:10.23937/2469-5769/1510011

Foundations of a Smart Toy Development for the Early Detection of Motoric Impairments at Childhood

Maria Luisa Martin-Ruiz, Miguel Angel Valero, Maria Linden, Susana Nunez-Nagy and Angeles Gutierrez Garcia

Article Type: Short Communication | First Published: November 11, 2015

The creation of adequate smart monitoring solutions at home can provide professionals with reliable information about the health status of a child. Furthermore, toys and playing are crucial for the overall development of a human being. Hence, the aim of this research is to improve the exactitude of traditional evaluation methods by embedding sensors into daily life toys that provide professionals with added value supplementary evidence enhanced by Decision Support Systems (DSS). It will be possible to detect potential motoric disorders in a standard child's development that might keep undetect...

 Open Access DOI:10.23937/2378-3397/1410030

Utilizing Patient Perspectives to Help Reduce Postoperative Readmission Rates

Vanessa Nomellini, Sarah E Tevis, Mary O'Leary, Maria Brenny-Fitzpatrick, Tamara LeCaire, Gregory D Kennedy, Emily R Winslow and Sharon M Weber

Article Type: Case Report | First Published: October 29, 2015

A total of 50 patients were enrolled in the study. There were no differences between the study patients and NSQIP patients in terms of age or gender, but there was a significant difference in ASA class (p < 0.01). The majority of patients had a scheduled follow up appointment, however 66% were readmitted before they were able to attend and 6% were readmitted from their postoperative clinic visit. When asked about suggestions to improve discharge planning, 50% were satisfied with the process. Among the other half, 32% suggested improving discharge instructions, 28% advocated for better communic...

 Open Access DOI:10.23937/2469-567X/1510014

Characterization of Human Influenza Viruses Propagated by Madin-Darby Canine Kidney Cells or Embryonated Eggs

Ewan P Plant, Laura Couzens, Samuel Mindaye, Elizabeth M Coyle, Surender Khurana, Hang Xie, Hana Golding, Maryna C Eichelberger and Zhiping Ye

Article Type: Research Article | First Published: November 22, 2015

The hemagglutination assay is a commonly used method to titer influenza virus. It relies on the interaction between virus particles and red blood cells being sufficient to prevent the settling of the blood cells. During additional assessment of human influenza virus stocks titrated by the hemagglutination assay we noted that virus grown in cell culture had a greater number of virus particles than analogous virus grown in eggs. Virus grown in both egg and Madin-Darby canine kidney cells are used for vaccine strain selection and to study antigenic variants by serological assays so it is importan...

 Open Access DOI:10.23937/2469-584X/1510008

Validation of Steroid-Free Immunosuppression Regimen after Liver Transplantation

Ken Fukumitsu, Ahmed Hammad, Toshimi Kaido, Kohei Ogawa, Yasuhiro Fujimoto, Akira Mori, Hideaki Okajima and Shinji Uemoto

Article Type: Original Article | First Published: November 27, 2015

Liver transplantation (LT) is performed worldwide with immunosuppression being an indispensable component of the perioperative management. Calcineurin inhibitors and steroids have been the most popular and widely used drugs for a long time. However, steroids hold long-term adverse effects, as increased susceptibility to infection, hyperglycemia, hyperlipidemia, obesity, hypertension and osteopenia. Furthermore, steroids have been implicated in hepatitis C (HCV) recurrence after LT and graft failure. The immunosuppression regimen at our center comprised originally tacrolimus and steroids....

 Open Access DOI:10.23937/2469-5777/1510026

Association between Sequential Organ Failure Assessment Score and In-hospital Deaths of Surgical, Critically Ill Patients with Sepsis

Noboru Harada, Ken Shirabe, Shinji Itoh, Hideaki Uchiyama, Motoyuki Yamagata, Fumiaki Kishihara, Takashi Maeda, Nao Kinjo, Kensaku Sanefuji, Yosuke Kuroda, Kazutoyo Morita, Tomoharu Yoshizumi, Toru Ikegami, Yo-ichi Yamashita, Yoshihiko Maehara and Study group of refractory disease in hepato-pancreato-biliary surgery

Article Type: Original Article | First Published: January 13, 2016

Sepsis, defined as infection-induced systemic inflammatory response syndrome (SIRS), is the leading cause of death in non-cardiac critically ill patients. In the United States, nearly 200,000 deaths per year are attributed to sepsis. Worldwide, as many as 20 million people may experience sepsis annually, with a mortality rate of about 35%. Sepsis involves multiple mechanisms, including the release of cytokines and the activation of the complement, coagulation and fibrinolytic systems....

 Open Access DOI:10.23937/2469-5777/1510025

Using D-β-Hydroxybutyrate Containing Solutions to Treat Hyperglycemia Induced by Shock or Injury Instead of Insulin may Circumvent Insulin Resistance and Provide Cells with the Energy Required to Maintain Vital Processes through Preserving Normal Mitochondrial Function without Causing Hypoglycemia

Veech RL and Valeri CR

Article Type: Review Article | First Published: January 13, 2016

Severe injury, infection and hemorrhage all cause insulin resistance and hyperglycemia. Insulin resistance blocks glucose entry into cells and the conversion of pyruvate to acetyl CoA impairing cellular energy production. During insulin resistance, glucose cannot enter muscle and fat cells nor can the cell metabolize the lactate given in lactated Ringer's solution with the occurrence of hyperglycemia. More importantly in all cells the mitochondrial pyruvate dehydrogenase (PDH) activity is decreased during insulin resistance leaving the cell deficient in substrates needed to power the Krebs cyc...

 Open Access DOI:10.23937/2469-5777/1510024

Liver Injury Associated with Chest Compression in Cardiopulmonary Arrest Patients

Takeshi Nishimura, Ayana Okamoto, Noritomo Fujisaki, Yoshiyuki Orihara, Ten Saita, Kunihiro Shirai, Isamu Yamada, Atsunori Nakao and Joji Kotani

Article Type: Review Article | First Published: January 12, 2016

We reviewed and summarized fifteen cases associated with liver injury following chest compression for CPA reported in Japan. In some cases, cardiopulmonary resuscitation (CPR) was administered by medical assistants such as doctors or medical technicians, but in other cases, CPR was given by bystanders. Five patients were male and eight were female, with ages ranging from 31 to 83 years old. Unfractionated heparin was administered to ten patients as a treatment for embolism or indication of veno-arterial extra corporeal membrane oxygenation (VA-ECMO), and other cases suffered from amniotic flui...

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