Risk of Legionellosis from Exposure to Water Aerosol from Industrial Cooling Tower
Margita Spalekova, Martina Kotrbancova, Miriam Fulova and Danka Simonyiova
Article Type: Original Article | First Published: June 05, 2019
Community-acquired cases of Legionella infection or even outbreaks can be attributed to inhalation of aerosols from devices such as hot water system, cooling towers, hot tubs, industrial equipment and indoor fountains. Legionellae survive in water in temperatures between 20°C and 50°C and tend to colonize particularly water systems rich of sludge, rust, biofilms and amoebae where they can multiply. Cooling towers (CT) in industry are used as heat-transfer devices in which warm water is cooled by evaporation in atmospheric air. Aerosols can transmit Legionellae to susceptible hosts, w...
Left Ventricular Pacing in Patients with Mechanical Tricuspid Valve Replacement
Sara Khodor, Shreya Mishra, Dany Sayad and Anant Kharod
Article Type: Case Report | First Published: June 01, 2019
In patients with mechanical tricuspid valve replacement (TVR), management of atrioventricular conduction abnormalities can be challenging given inaccessibility of the right ventricle (RV) with an endocardial pacing lead. While implantation of an epicardial lead may serve as an alternative; it requires invasive surgical placement and is not an ideal option in patients with prior thoracotomy. The development of specialized leads have made lead implantation via coronary sinus (CS) an attractive alternative for pacing in this patient population....
Relationship between Hypovitaminosis D and Cardiac Abnormalities in Pre Dialysis Chronic Kidney Disease
Maria Carolina Neves, Luis Sette, Monica Becker, Lucila Valente and Brivaldo Markman Filho
Article Type: Research Article | First Published: June 01, 2019
The presence of structural and functional changes in the left ventricle (LV) are good predictors of cardiovascular events in patients with chronic kidney disease (CKD) and are associated with decreasing renal function. Studies in CKD patients on hemodialysis evidenced associations of serum 25-OH vitamin D (vit D) with myocardial function and structural changes. However, it is not known whether serum vit D is associated with Doppler echocardiogram (ECHO)-based cardiac changes in patients with CKD managed conservatively....
Hyperlipidemia Management in Proprotein Convertase Subtilisin- Kexin Type 9 (PCSK 9) Inhibitors Era
Abdulhalim Jamal Kinsara
Article Type: Original Article | First Published: June 01, 2019
Significant improvement in control of cardiovascular risk factors has been driven by performance measurement that focused on attainment of specific risk factor thresholds for blood glucose, lipids and blood pressure. Diet, statin and ezetimibe have reasonably controlled hyperlipidemia. However the discovery of proprotein convertase subtilisin-kexin type 9 inhibitors has given new hope of reaching the target lipid profile especially in the high-risk group and familial hypercholesterolemia. Here with we reviewed the current data and explore the cardiovascular prevention effect of this group....
Fast Track Colorectal Surgery for Deep Endometriosis: A Prospective Randomized Trial
Irene Gentile, MD, Roberto Rossini, MD, Marco Scioscia, MD, Davide Brunelli, MD, Marcello Ceccaroni, MD and Giacomo Ruffo, MD
Article Type: Original Article | First Published: June 01, 2019
Application of fast track protocols in laparoscopic colorectal surgery has been assessed in oncological cases with contrasting results. This study was to assess the feasibility and advantages in a group of young women suffering from bowel endometriosis. Over one year, 227 women were recruited for this prospective randomized study on fast track protocol for laparoscopic surgery for bowel endometriosis. Patients were allocated to a perioperative fast-track or conventional care in a 1:3 ratio and clinical outcomes and costs were evaluated....
Self-Esteem as the Mediating Factor between Parenting Styles and Creativity
Huong TM Pham and Betsy Ng
Article Type: Review Article | First Published: June 03, 2019
Creativity is increasingly valued as a skill for the future workplaces. Educators and employers are paying more and more attention to creativity training, the effectiveness of which relies on an understanding of creativity influencing factors. Yet, the seed for creativity might be sawn early in life and nurtured through years in family and school. Links between parenting styles and creativity have been reported in literature. However, parenting styles only explain for a small variation in creativity, suggesting the roles of other factors. This paper goes further by exploring the links between ...
Hepatitis B Core Antibody Prevalence among Voluntary Blood Donors in Thailand
Kriangsak Chaiwong, Wilawan Saekram, Panya Thunnok, Sineenart Oota, Sonu Bhatnagar and Ubonwon Charoonruangrit
Article Type: Brief Report | First Published: June 03, 2019
Hepatitis B core (anti-HBc) antibody is an effective marker for occult Hepatitis B virus (HBV) infection and is an integral part of blood donor screening in many countries. This study was aimed to evaluate the prevalence of anti-HBc antibodies among voluntary blood donors in Thailand and its significance to reduce the risk of transfusion transmitted HBV infection. A total of 3,197 voluntary blood donor samples that were pre-screened non-reactive for HBs-Ag serology and HBV ID-NAT were tested for anti-HBc Total and IgM antibody and anti-HBs titers on ARCHITECT i6000 (Abbott Diagnostics, Illinoi...
Molecular Basis of Pulmonary Hypertension
Ambrin Farizah Babu
Article Type: Review Article | First Published: May 31, 2019
Pulmonary hypertension is a life threatening incurable disorder. The advances in physiology, genetics, and molecular biology have greatly improved our understanding of the cellular and molecular mechanisms underlying the disorder. In this review, the recent progresses in the understanding of molecular mechanism are presented. Many studies show that pulmonary hypertension is caused due to mitochondrial dysfunction, endothelin-1, prostacyclin and serotonin. These findings and their exploitation will hold promise to find novel treatment options for patients....
Variable Left Ventricular Dyssynergy in Recurrent Stress Induced Cardiomyopathy
Timothy E Paterick MD, JD, MBA
Article Type: Case Report | First Published: May 31, 2019
Recurrent stress-induced cardiomyopathy with variable regional location of left ventricular dyssynergy is an unusual clinical presentation and may allow potential insights into the pathophysiologic mechanisms underlying the development of the variable subtypes of stress induced cardiomyopathy. This case report reveals a patient with reverse Takotsubo cardiomyopathy and apical Takotsubo cardiomyopathy within a three-week period. The discussion explores the potential pathophysiologic mechanisms responsible for the variable left ventricular regional involvement in stress-induced cardiomyopathy......