ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2378-3419/2/1/1012

Phase I Clinical Study of Survivin-Derived Peptide Vaccine for Patients with Advanced Gastrointestinal Cancers

Fukino Satomi, Hiroaki Shima, Toru Mizuguchi, Toshihiko Torigoe, Goro Kutomi, Yasutoshi Kimura, Yoshihiko Hirohashi, Yasuaki Tamura, Tomohide Tsukahara, Takayuki Kanaseki, Akari Takahashi, Hiroko Asanuma, Yoichi M. Ito, Hiroshi Hayashi, Osamu Sugita, Noriyuki Sato and Koichi Hirata

Article Type: Original Article | First Published: February 04, 2015

Survivin is a member of the Inhibitor of Apoptosis Protein (IAP) family. It is expressed in fetal tissues but not in normal adult tissues. Since Survivin is over expressed in various types of tumor tissues as well as tumor cell lines, it is considered to be suitable as a target antigen for cancer vaccine therapy. We identified an HLA-A24-restricted antigenic peptide, SVN-2B (AYACNTSTL), derived fr...

 Open Access DOI:10.23937/2378-2951/1410020

Relationship between Insulin Levels and Coronary Atherosclerosis in Newly Diagnosed Diabetes Mellitus and Impaired Glucose Tolerance

Naohiko Nemoto, Rintarou Nakajima, Kennji Ymazaki, Makoto Utsunomiya, Masaki Hori, Shingo Ito, Itaru Yokouchi, Masamichi Wada, Masanori Shiba, Hisao Hara, Hidehiko Hara, Takuro Takagi, Kaoru Sugi and Masato Nakamura

Article Type: Review Article | First Published: February 06, 2015

Background: While some therapies implemented for newly diagnosed Diabetes Mellitus (DM) or impaired Glucose Tolerance (IGT) are effective in preventing cardiovascular events, investigations of coronary plaque in patients with newly diagnosed DM or IGT are lacking. Methods: We evaluated 96 patients with acute coronary syndrome. The External Elastic Membrane (EEM), Lumen Cross-Sectional Area (CSA), ...

 Open Access DOI:10.23937/2378-2951/1410019

Physical Examination of the Cardiovascular System

John P. Higgins

Article Type: Review Article | First Published: January 27, 2015

The physical examination, while frequently not performed well, is critical to the diagnosis and management of cardiovascular disorders. This paper describes a basic cardiovascular physical examination and explains findings, with the goal of improving skills in this area....

 Open Access DOI:10.23937/2377-4630/2/1/1019

Proposing a Novel Concept to Evaluate Safety of Supraglottic Devices Regarding Seal Pressure during Laparoscopic Surgery

Jose M. Belena, Monica Nunez and Alfonso Vidal

Article Type: Opinion | First Published: January 23, 2015

It is a fact that Supraglottic Airway Devices (SAD) are currently present at many clinical scenarios in anesthesia and they are also a good alternative to endotracheal intubation in some routine anesthetic procedures. Nowadays, laparoscopy is one of the most common and widely established surgical techniques. This procedures increase airway pressure due to the peritoneal insufflation and consequent...

 Open Access DOI:10.23937/2469-5696/1410005

A Case of Localized Neuroblastoma in Caffey Disease, with Early and Uncommon Progression

Manuela Pagano, Chiara Galletto, Maurizio Bianchi and Franca Fagioli

Article Type: Case Report | First Published: January 21, 2015

Background: Caffey disease is a rare syndrome caused by mutation in the alpha-1 collagen type I gene, not described in literature as a predisposing condition to cancer development. Observation: We report a case of a 6-years-old female diagnosed with Caffey disease that developed a localized neuroblastoma. The patient had a poor clinical and radiological response with unusual disease dissemination ...

 Open Access DOI:10.23937/2469-5696/1410004

Diverse Genotype Presentation of the Saudi-Type Poly A Signal Mutation (αTsaudiα) in the Population of Bahrain

Nabeel Al Moamen, Fawzia Mahdi, Ahmed Thabet, Rugaya Abbas, Ebtihal Salman and Ahmed Al Alawi

Article Type: Letter to Editor | First Published: January 15, 2015

A total of 1187 patients with α-thalassemia phenotype presentation have been recruited for this investigation. Preliminary diagnosis of α-thalassemia was based on low hematological indices (MCV and MCH) of the red blood cells and/or persistently low hemoglobin levels, along with low or normal levels of HbA2 and absence of iron deficiency. Th molecular diagnosis of α-thalassemia was ...

 Open Access DOI:10.23937/2378-346X/1410010

Macular Multifocal Granular Hyperfluorescence on Fluorescein Angiography

Taiichi Hikichi

Article Type: Research Article | First Published: January 30, 2015

Purpose: To investigate the causes of multifocal granular hyperfluorescence at the macula on Fluorescein Angiography (FA) in Japanese patients. Methods: I retrospectively studied 1,457 consecutive Japanese patients (1,457 eyes) who underwent digital simultaneous FA and indocyanine green angiography (ICGA). Results: One hundred forty-seven of the 1,457 eyes had multifocal granular hyperfluorescence...

 Open Access DOI:10.23937/2378-346X/1410009

Optic Disk Size Assessment Techniques: Photo Essay

Sourabh Arora, Helen Chung and Karim Damji

Article Type: Case Report | First Published: January 25, 2015

Measuring optic disc size is an essential part of the optic nerve head for evaluation for glaucoma. Large discs that appearing to have large cups may in fact be physiologic because of normal neuroretinal rim area. Small discs may appear to have a normal cup to disc ratio, but have decreased neuroretinal rim area in association with glaucoma. We illustrate relevance of these points with respect to ...

 Open Access DOI:10.23937/2378-3664/1410007

Bnct and Nanoparticles: A Long Way to a Routine Clinical Method

Cesare Achilli, Stefania Grandi, Annarita Ciana and Giampaolo Minetti

Article Type: Commentary | First Published: January 22, 2015

We have recently had the chance to read the editorial 'Boron Neutron Capture Therapy of cancer as a part of modern nanomedicine', by Alexander V. Safronov, in which the potential of nanomaterials as boron-carriers for the treatment of many types of tumors by BNCT is discusses. The author argues that "Most of the modern papers on BNCT report 'potential' BNCT agents [...] and don't even include cell...

 Open Access DOI:10.23937/2377-3634/1410019

Magnesium and Type 2 Diabetes: An Update

Mario Barbagallo and Ligia J. Dominguez

Article Type: Review Article | First Published: January 26, 2015

The link between magnesium (Mg) deficiency and type 2 diabetes mellitus is well known. Type 2 diabetes is frequently associated with both extracellular and intracellular Mg deficits. A chronic latent Mg deficit or an overt clinical hypomagnesaemia is common in subjects with type 2 diabetes, especially in those with poorly controlled glycemic profiles. Insulin and glucose are important regulators o...

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Gene-Specific Promoter Methylation Status in Hormone-Receptor-Positive..
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Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate..
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Electron Microscopic Analysis of Silicate and Calcium Particles..
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Effects of chest physical therapy in patients with non-tuberculous mycobacteria
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A Community-Based Exercise and Support Group Program Improves Quality..
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