Z-Calcaneal Osteotomy: Radiographic Assessment of Correction in the Valgus Hindfoot
Daniel Dawson, A Walls and J Wong
Article Type: Original Article | First Published: June 24, 2019
Elective reconstruction in the valgus hindfoot is a complex and varied field of orthopaedic surgery. Often multiple procedures, both bony and soft tissue are required. The surgical aims are to create a plantigrade foot, restore hindfoot alignment and re-create the medial longitudinal arch in an attempt to allow more normal biomechanical function. Invariably a calcaneal osteotomy is required to correct hindfoot alignment. There are various methods of performing a calcaneal osteotomy....
Continuous Glucose Monitoring Guided Assessment of Concentrated 200 IU/Ml rDNA Human Premix 30/70 Insulin in Type 2 Diabetes Mellitus Patients
Hemant Thacker, MD, MRSH, FACE, FACP, Jothydev Kesavadev, MBBS, MD, FRCP, Shahu Ingole, Jayesh Rajgopal and Rishi Jain
Article Type: Original Article | First Published: June 22, 2019
Many patients with type 2 diabetes mellitus (T2DM) are on insulin analogues which are costly as well as usage of higher units of insulin on a daily basis increases the cost of the monthly therapy. Concentrated insulin are a way forward for patients who needs higher units of insulin especially Human insulin which address the issues of higher cost and the need for higher concentration in the same or lesser volume of insulin. However, data on 24-hour glycemic control with concentrated insulin in Indian T2DM patients are limited. Hence, this study was conducted to study 24-hour glycemic control in...
Utility of Magnetic Resonance Imaging (Imaging) in Target Volume Definition for Radiosurgery of Acoustic Neuromas
Omer Sager, Ferrat Dincoglan, Selcuk Demiral, Hakan Gamsiz, Bora Uysal, Bahar Dirican and Murat Beyzadeoglu
Article Type: Original Article | First Published: June 20, 2019
Acoustic neuromas, also known as vestibular schwannomas are benign and slow-growing tumors arising from neural crest-derived Schwann cells. Treatment of acoustic neuromas targets to achieve local control while preserving hearing without comprimising cranial nerve functionality. In this context, radiosurgery in the form of Stereotactic Radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) offer viable therapeutic options for effective management. Multimodality imaging has gained utmost priority for improved target defnition for radiosurgery. In this study, we assessed the utility ...
Frailty as a Prognosis Factor in Cancer for the Elderly
Miguel Angel Acosta-Benito, Rosa Ana Garcia-Pliego, Jaime Barrio-Cortes and Veronica Rodriguez-FernAndez
Article Type: Research Article | First Published: June 20, 2019
Frailty is a geriatric syndrome related to adverse health outcomes in the elderly, due to a decrease systems' functional reserve. Cancer is a common pathology in the elderly, and we need tools for identifying the response to treatment and prognosis of elderly cancer patients. This short revision aims to assess the significance of the detection of frailty in the elderly patient with a tumor as a possible prognostic factor in terms of mortality, and the impact of the 2013 Frailty Consensus in the research activity....
Current Recommendations of Radioactive Seed ~ (125)I Implantation in Lung Brachytherapy: Moving Forward in Medical Care
Wang Yuchan, Yuan Gengbiao, Lee Changyi, Ran Lifeng and Yang Wei
Article Type: Review Article | First Published: June 20, 2019
Isotopes of radioactive iodine have a persistent lethal effect on the uncontrolled proliferation of tumor cells with a definite curative effect on tumors. It has been proved, up to 87.2% of 3-year's survival rate that could be achieved by radioactive seeds. Iodine-125 radioactive seeds have a long half life and low energy with excellent stable outcomes. Various effective isotopes with advanced techniques are used to place radioactive sources directly into a tumor, tumor bed in treating lung cancer....
Breast Cancer Survivors: Is Routine 'Mammographic Only' follow up Imaging Enough or is it Time for Personalised follow up?
Gaurav Jyoti Bansal, Thomas Telford and Kevin Pinto
Article Type: Original Article | First Published: June 20, 2019
Breast cancer is the most common cancer in women, accounting for approximately 15% of all cancers. Over 85% of these people survive beyond 5 years after diagnosis, due to continual progressions in early detection and treatment quality. Despite advances in detection and treatment, 20-30% of patients develop local relapse or distant metastasis. Molecular subtyping of breast cancers based on receptor expression has been introduced in clinical practice and has developed into an important tool in predicting prognosis and constructing personalised management plans for breast cancer sufferers....
Breast Fibromatosis: Case Report, Case Series, and Mini Review
Alicia Huff Vinyard, DO, Rachel Berger, MS-IV, TolgaOzmen, MD and Eli Avisar, MD
Article Type: Case Report | First Published: June 15, 2019
Fibromatosis of the breast is a rare, benign tumor, lacking metastatic potential, but can be aggressive and create issues with loco-regional control if not adequately treated. In the literature, fibromatosis of the breast is often discussed only in case reports and small case series. The consensus on treatment remains wide local excision, however, other therapies have been described. In discussion of an interesting case presentation of what we have defined as secondary breast fibromatosis, we reviewed relevant treatment modalities and discussed proper treatment for this patient. Our aims of th...
Iatrogenic Related to the Knowledge Deficit of Patient Safety in the Care: A Descriptive Analysis
Eliza Miranda Ramos, Matheus Dullius Lima, Valter Aragao do nascimento, Ph.D and Elaine Cristina Fernandes Baez Sarti
Article Type: Research Article | First Published: June 22, 2019
Iatrogenic conditions are those that result from the intervention of the multidisciplinary health team, whether correct or incorrect, justified or not, but which result in detrimental consequences for the patient's health. Few studies have focused on assessing the risks to patients, especially those hospitalized in emergency and intensive care services, and only in the last decades attention has been drawn to the importance of these problems...
ABO Blood Group: Its Relationship with Anthropometric Parameters Among Young Adult Nigerians of Yoruba Ethnicity
Asafa MA, Ogunlade O, Bolarinwa RA, Bisiriyu LA and Asafa ST
Article Type: Research Article | First Published: June 17, 2019
It had been established that ABO blood group system associated with some diseases or disorders. The objective of this study was to determine the effect of ABO blood group on anthropometric indices among apparently healthy young adults of Yoruba ethnicity. Eighty apparently healthy young adults who were purposely selected participated in the study after screening for the ABO blood groups following the standard protocol. They were divided into four equal groups; 20 in each of blood groups A, B, AB and O who were age- and sex- matched....
The Role of Prolyl Oligopeptidase in Microtubule-Associated Processes and Cognitive Impairment
Nuria Trallero, Ariadna Anunciacion-Llunell, Roger Prades and Teresa Tarrago
Article Type: Review Article | First Published: June 29, 2019
Prolyl oligopeptidase (POP) is a cytosolic serine protease with prominent expression in the brain. Inhibition of this enzyme leads to cognition-enhancing and neuroprotective effects in animal models with cognitive deficits. However, the biological function of POP remains unknown. Although in the past it was though that its catalytic activity was responsible for its physiological role, lately it has been hypothesized that POP is involved in the inositol pathway and that it interacts with several proteins....