Muscle Ultrasound in Inflammatory Myopathies: A Critical Review
Kristofoor E Leeuwenberg and Jemima Albayda
Article Type: Review Article | First Published: February 11, 2019
Muscle ultrasonography is an upcoming tool in the evaluation of neuromuscular disorders. It is easily applicable in multiple clinical settings, has no contraindications, and provides a cost-effective alternative to other imaging modalities such as MRI. However, a known disadvantage of ultrasound is its dependence on examiner expertise. Furthermore, the assessment of muscle quality is done mainly through an assessment of muscle echo intensity, which is affected by machine/system settings, hampering comparison across centers. Over the years new methods have been developed to make results more ob...
Impact of Rapid Microorganism Identification Using Two Multiplex PCR Platforms on Timing of Antimicrobial Therapy
Natasha N Pettit, Zhe Han, Angella Charnot-Katsikas, Jennifer Pisano and Vera Tesic
Article Type: Research Article | First Published: February 11, 2019
Strategies to improve time to administration of appropriate, effective antimicrobial therapy can improve patient outcomes. We sought to retrospectively assess if the earlier identification of blood pathogens and their resistance determinants with multiplex PCR platforms could have an impact on time to initiate appropriate antimicrobial therapy. All patients with monomicrobial positive blood cultures from March to June 2013 were included in the retrospective chart review analysis. We evaluated the standard of care results, assessing time to effective therapy (time from positive blood culture Gr...
Analysis of Protocols of Bucal Hygienization in Patients in the Intensive Therapy Unit (ICU)
Gleycielly da Mota Oliveira Souza, Carolina de Lima Borges, Rosa Natalia Rendall dos Santos Ratis and Vivian Kelly Leite Pedrosa
Article Type: Research Article | First Published: February 09, 2019
Constant care should be adopted for the treatment of patients hospitalized in Intensive Care Units (ICUs). It is necessary to cover the proper oral hygiene habit given to the interrelationship between oral and systemic diseases, in the development of nosocomial pneumonia. Considering these deficiencies and elucidated problematizations, the present study aimed to evaluate the oral hygiene protocols in patients hospitalized in the Intensive Care Unit. National and international protocols and studies, published between 2000 and 2017, were analyzed regarding the hygiene process, the proposed metho...
The Influence of Human T-Lymphotropic Virus 1 on Patients Coinfected by the Helminth Strongyloides stercoralis
Larissa Rodrigues Bosqui, Taylon Felipe Silva, Raquel Arruda Sanfelice, Lais Fernanda Machado, Erika Caroline Steinle, Bianca Arranzato Bertasso, Marina Leticia Rezende Mantovani, Gabriela de Alcantara Dalevedo, Milena Menegazzo Miranda-Sapla, Ivete Conchon-Costa, Wander Rogerio Pavanelli, Francine Nesello Melanda and Idessania Nazareth Costa
Article Type: Review Article | First Published: February 09, 2019
Strongyloides stercoralis is the helminth which causes strongyloidiasis, a neglected disease, with a global prevalence estimated at 60 million people infected, principally in tropical regions. The parasite’s proliferation occurs mainly in immunosuppressed hosts, in particular, patients carrying Human T-lymphotropic virus 1 (HTLV-1), which is responsible for the infection of cells of the immune system. As a result, we aimed to identify and discuss clinical and pathological aspects of infection by S. stercoralis in patients carrying HTLV-1. This is an exploratory study, of the literature revie...
Craniofacial, Tongue, and Speech Characteristics in Anterior Open Bite Patients of East African Ethnicity
Meng-Zhao Deng, Daniel F Leotta, Greg J Huang, Zhi-He Zhao and Zi-Jun Liu
Article Type: Original Article | First Published: February 09, 2019
The role of the tongue in the pathophysiology of anterior open bite (AOB) is poorly understood. This study characterized tongue morphology and functional motion, craniofacial skeletal pattern and upper airway space, and speech function in East African children with and without AOB. Ten 9-12 year-old children of East African descent were recruited, five with AOB and five as control. Cone-beam CT scans, ultrasound imaging of the tongue during chewing and swallowing, and inter-labial pressure and lip muscle activity during lip closure and speech were taken in all subjects....
Penetrating Abdominal Trauma with Vascular Injury: Case Report
Rodolfo Franco Marquez, Marcela Anahi Narro Martinez, Pedro Chavez Jimenez, Oscar Rene Garcia de Leon and Estefania Boland Rodriguez
Article Type: Case Report | First Published: February 07, 2019
Traumatic injuries account for 9.6% of the global burden of disease, they represent the third most common cause of death in young adults and adolescents among patients admitted to hospital facilities; penetrating abdominal trauma remains an important cause of mortality and morbidity. This type of lesions can cause vascular injuries that are associated with massive hemorrhage and could develop physiologic exhaustion, resulting in high reported mortality. Inferior's cava injuries secondary to penetrating trauma are rare, accounting for approximately 0.02% of gunshot wounds to the abdomen....
An Iatrogenic Foreign Body in the Maxillary Sinus: Report of an Unusual Case
Fatima Betul Basturk, PhD, Dilek Turkaydin, PhD, Sertac Aktop, PhD and Hesna Sazak Ovecoglu, PhD
Article Type: Case Report | First Published: February 07, 2019
Dental practitioners frequently encounter with instrument fracture during root canal treatment. However, these fractures generally occur inside the root canals. It is not usual that high speed rotary instruments snap and go further to important anatomical landmarks. In our case report, a high-speed Gates-Glidden drill perforated the root and was introduced into the left maxillary sinus during a routine root canal treatment. The dental and surgical management of the case are described and the possibly more serious sequelae are discussed. Practitioners must take great care during dental treatmen...
Potential of Polycaprolactone Nanofiber Scaffold for Ex Vivo Expansion of Cord Blood-Derived CD34+ Hematopoietic Stem Cells
Seyed Hadi Mousavi, Saeid Abroun, Masoud Soleimani and Seyed Javad Mowla
Article Type: Research Article | First Published: February 07, 2019
An efficient and practical ex vivo expansion of cord blood hematopoietic stem cells as an alternative source of HSC transplantation is crucial in understanding the potential of HSC transplantation in treating or supportive therapy in a variety of hematologic and non-hematologic disorders. The aim of this study was an ex vivo expansion of cord blood hematopoietic stem cells in a novel three-dimensional polycaprolactone nanofiber scaffold coated with collagen....
Laparoscopic Radical Nephrectomy in Patients with Locally Advanced Renal Cell Carcinoma: Initial Experience
Alper Bitkin and Lokman Irkilata
Article Type: Research Article | First Published: February 06, 2019
In this study, we evaluated the results of laparoscopic nephrectomy cases performed in patients with locally advanced renal cell carcinoma. Between July 2015 and December 2018, 14 patients underwent laparoscopic nephrectomy for locally advanced renal tumor. The duration of operation, blood loss, duration of hospital stay, perioperative complications and follow-up time were evaluated. Nephrectomy improves survival in patients with locally advanced renal tumors. Although the laparoscopic approach has difficulties in these patients, the laparoscopic nephrectomy is a minimally invasive treatment t...
An Exploration of the Roles of Certified Child Life Specialists & Registered Play Therapists in the United States
Julie Lerwick, PhD, LPC, NCC, RPT
Article Type: Review Article | First Published: February 06, 2019
In the United States pediatric hospitals and healthcare organizations are becoming more familiar with the value of Child Life Specialists to partner with children and their families to offer information, preparation, and stress reduction interventions to ease the potential negative emotional impact of a healthcare experience. To that end, Child Life Specialists have a unique role, which is not often understood by other healthcare providers. Historically casually regarded as "the hospital play ladies" Child Life Specialists offer more than simply play. They are child development experts that he...