Response Prediction to Neoadjuvant Chemotherapy Prior to Interval Debulking Surgery and the Outcome of Responders Compared to Nonresponders
Michal Levy, Joseph Menczer, Mona Boaz, Ayelet Wandel, Yossi Mizrachi and Tally Levy
Article Type: Research Article | First Published: October 17, 2018
Neoajuvant Chemotherapy (NACT) followed by Interval Debulking Surgery (IDS) is an acceptable therapeutic approach for selected patients with advanced stage Ovarian Carcinoma (OvC) and Primary Peritoneal Carcinoma (PPC) patients. Our aim was to assess whether the combined presence of reduction of the diameter of the largest tumor mass and of the CA125 level predict response to Neoadjuvant Chemotherapy (NACT). Clinicopathological data were abstracted from medical records of consecutive OvC and PPC patients who received paclitaxel + carboplatin NACT and underwent IDS. Computed tomography (CT) ima...
Physical Activity in the Prevention of Abdominal Obesity: Type, Duration and Intensity
Francisco Jose Gondim Pitanga, Cristiano Penas Seara Pitanga and Carmem Cristina Beck
Article Type: Opinion | First Published: October 17, 2018
To suggest the type and dose (duration and intensity) of physical activity more adequate to prevent abdominal fat in adults. The evidences that were presented are part of studies on physical activity and abdominal fat published in the national and international literature. Physical activity (aerobic and resistance exercises), with a prolonged duration of moderate intensity for men and walking or m...
Identification and Molecular Epidemiology of Mycobacterial Isolates in Kayseri/Turkey
Murat KARAUZ, A Nedret KOC and Altay ATALAY
Article Type: Original Article | First Published: October 17, 2018
Early diagnosis and treatment of tuberculosis (TB) patients are the most effective ways to protect society from this disease. The objectives of this study were to evaluate the molecular epidemiology of mycobacterial strains by repetitive sequence PCR (rep-PCR) using the DiversiLab System method at Kayseri in Turkey. A total of fifteen clinically sample isolated Mycobacterial strains were identified as M. tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM) by the rep-PCR method (bioMerieux), SD (Standard Diagnostics) rapid tests. Genotyping was performed by the rep-PCR method and...
Pathogenic Beliefs and their Relevance in Psychotherapy: A Written Case Study
Jennifer Kadur, Irina Flaig, Jana Volkert, Isa Sammet and Sylke Andreas
Article Type: Case Study | First Published: October 17, 2018
Goals of this single-case study are to assess whether tests according to Control Mastery Theory (CMT) can be reliably identified by trained raters and to examine whether the Psychotherapy Process Q-Sort method can adequately represent the test situation. A single case was analyzed by well-trained psychology graduates on the basis of the Plan Formulation Method. The interrater reliability of the identified tests was examined. In addition, the tests were classified according to the Psychotherapy Process Q-Sort....
Rheumatologic Diseases as Paraneoplastic Syndromes - A Paradigmatic Case
Ines Rego de Figueiredo, Rita Vieira Alves, Sara Guerreiro Castro, Filipa Lourenco, Ana Margarida Antunes, Heidi Gruner and Antonio Panarra
Article Type: Case Report | First Published: October 15, 2018
Rheumatic diseases can be a paraneoplastic syndrome for an occult neoplasia. Some syndromes are more characteristic than others. In this case report, we present a patient with musculoskeletal symptoms suggestive of both carcinomatous arthritis and polymyalgia rheumatica that was shown to have adenocarcinoma of the lung. The musculoskeletal symptoms accompanied the course of the disease, disappeari...
Impact of Core Electronic Health Record Functionalities on Cardiovascular Disease Preventive Health Services for Underserved Patients
Christopher K Rogers
Article Type: Research Article | First Published: October 15, 2018
Examine differences in the associations between core Electronic Health Record (EHR) functionalities for public and population health, care coordination, patient engagement, and quality improvement on the provision of recommended Cardiovascular Disease (CVD) preventive health services provided at Primary Care Visits (PCVs) for CVD at-risk adults with Medicaid and those with private insurance. Utilizing a nationally representative survey of ambulatory care visits by patients at risk for CVD in 2014 and 2015, binary logistic regression models examined the associations between core EHR functionali...
Blue Finger Syndrome in an Elderly Patient
Castillo-Santizo JJ, Alvarez-Perez E, Gonzalez-Lopez A, Blanco-Rubio C, Ortega-Calvo M and Gabaldón-Rodriguez I
Article Type: Case Report | First Published: October 15, 2018
This article presents a case of an 88-year-old man who shows blue-violaceous discoloration on his fingers and toes, with a greater intensity on the third finger of right hand and the first, second and third toe of his right foot. The patient had been recently diagnosed with atrial fibrillation and met the criteria for oral anticoagulation with acenocoumarol, which had started two weeks earlier. Wh...
Insulin Resistance Modification is a Game Changer for Type 2 Diabetes Treatment Strategy
Article Type: Review Article | First Published: October 15, 2018
Insulin resistance, appearing years before diabetes main diagnostic sign, hyperglycemia, stands in the origin of type 2 diabetes (T2DM), generated by complex impairment of a spectrum biochemical processes the most important of which is the failure of phosphatidylinositol 3-kinase enzymatic chain responsible for glucose uptake and endothelial nitric oxide (NO) synthase activation. Therefore in cond...
Set Up of "Longitudinal Care" Paradigm in Contemporary Family Medicine and Community Nursing
Manuel Ortega-Calvo and Manuel Angel Calvo-Calvo
Article Type: Original Article | First Published: October 15, 2018
The paradigm constitutes the development of what is called "normal science". On the other hand, one of the essential characteristics of medical and nursing practices in primary health care (PHC) is the longitudinal heed of human beings. William Rathbone VI was a merchant and businessman noted for his philanthropic work. In 1859 his appreciation for the services of a nurse, Mary Robinson, engaged to care for his dying wife, prompted him to campaign for a system of district nursing to enable the poor to benefit from similar care. Florence Nightingale advised him to establish a training home in L...