ClinMed International Library

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.

ClinMed International Library

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Articles Published

All articles are fully peer reviewed, free to access and can be downloaded from our ClinMed archive.

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Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access

The Main Neurological Dysfunctions in Hyperargininemia-Literature Review
Andre Eduardo Almeida Franzoi, Marcelo Manukian Patti, Debora Delwing Dal Magro and Daniela Delwing de Lima
Article Type: Original Article | First Published: June 25, 2018
Arginine is an essential amino acid. This compound plays an important role in various body functions including cell division, wound healing, removal of ammonia, immune function, and release of hormones. The arginase 1 is a hepatic enzyme that is the faulty component in urea cycle. The urea cycle is represented in Figure 1 with focusing on arginine. When in normal function, the enzyme catalyzes the reaction of conversion of the arginine in ornithine and urea. However, in hyperargininemia, this enzyme is faulty and the concentrations of arginine in the plasma increases.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2378-3001/1410074


 Open Access

Potential of Carcinogenesis Induced by John-Cunningham Virus and Crude-Oil Extracts
Shih-Chao Lin, Christopher Z Lien and Chi-Chen Lin
Article Type: Short Communication | First Published: July 13, 2018
John-Cunningham virus (JCV) has been recognized as a major contributor to progressive multifocal leukoencephalopathy (PML) in humans, especially in immunodeficient patients. While the prevalence rate of PML in human populations could be up to 80%, the occurrence of tumorigenesis is around 0.07%. Thus, we investigated whether crude-oil extracts could synergistically increase the carcinogenesis along with T antigen from JC virus in vitro. Here we analysed the cell cycle distribution and cytotoxicity of T-antigen of JCV transformed and non-transformed cells by flow cytometry and MTS assay.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/iamm-2017/1710003


 Open Access

An Asymptomatic Haemorrhagic Pleural Effusion Mimicking Extra-Pulmonary Tuberculosis in a Young Woman with Thoracic Endometriosis Syndrome: A Case Report
Vipula R Bataduwaarachchi, Jayani Jayawardhana, Champa Weerasinghe, Aflah Sadikeen, Roshana Constantine and Kirthi Gunasekara
Article Type: Case Report | First Published: July 14, 2018
A young woman presented with an asymptomatic recurrent right sided pleural effusion. Pleural fluid full report showed neutrophilic and haemorrhagic effusion. Adenosine deaminase level in the pleural fluid was elevated and the Mantoux test was positive. Microbiological diagnosis was negative, and she was started on anti-tuberculous therapy on clinical grounds for extrapulmonary tuberculosis. Diagnostic Thoracoscopy revealed characteristic appearance suggestive of thoracic endometriosis which was confirmed by histology.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2378-3516/1410082


 Open Access

Tuberculosis Diagnosis in Private Independent Laboratories in Kampala- Uganda Implications for TB Control in the City
D Lukoye, D Okello, S Namatovu, A SSebagereka, K Mutesasira, Mabumba Eldad, M Nandala and P Suarez
Article Type: Research Article | First Published: July 13, 2018
Tuberculosis remains the greatest killer globally. Uganda, one of the highest TB burden countries has a rapidly growing private medical sector. Although a large proportion of patients first seek care from the private sector, there is very little if any literature about participation of private independent laboratories in diagnosis of TB. We aimed at assessing this and the extent to which diagnosed TB patients are linked to care.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2378-3516/1410081


 Open Access

Immunotherapy and the Immune Infiltrate in Pediatric Brain Tumors: An Illustration and Review of the Unique Challenges Facing Immunotherapy for Pediatric Oncology
Ashley S Plant and Eugene I Hwang
Article Type: Review Article | First Published: July 13, 2018
Immunotherapy for pediatric oncology is a robust and prolific area of active research and has changed the face of treatment for some cancers, such as, B cell acute lymphoblastic leukemia (ALL) and neuroblastoma. However, the field faces challenges and hurdles unique to the pediatric population especially in the area of neuro-oncology.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2378-3672/1410028


 Open Access

Silent Sinus Syndrome: A Case Report and Review of Literature
Sumana CV and Suhel Hasan
Article Type: Case Report | First Published: July 12, 2018
Silent sinus syndrome is a rare clinical entity affecting the maxillary sinus, causing progressive enophthalmos and hypoglobus resulting from retraction of maxillary sinus walls with increase in the orbital volume. We report a case of a 29-year-old male who presented with painless enophthalmos, without any disturbances in vision or ocular movements, with no history of sinusitis in the past.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2572-4193.1510045


 Open Access

Congenital Cytomegalovirus Infection Presenting as Severe Conjugated Hyperbilirubinemia on First Day of Life
Aaradhana Singh and Ravi Sachan
Article Type: Case Report | First Published: July 12, 2018
Congenital Cytomegalovirus infection (CMV) has varied presentations ranging from asymptomatic to involvement of multiple organ systems like central nervous system, gastrointestinal, hepatic and hematopoietic. Jaundice is a manifestation of congenital CMV presenting as neonatal hepatitis or cholestasis jaundice. We report a case of severe conjugated hyperbilirubinemia presenting on the first day of life that was diagnosed as a case congenital CMV on further workup.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2469-5769/1510035


 Open Access

High Grade Uterine Sarcoma with Concurrent Metastatic Adenocarcinoma to the Uterus: A Case Report
Luke King, Radhika P Gogoi, Christopher Hummel, Zongming Chen and Ashlee Smith
Article Type: Case Report | First Published: July 12, 2018
A 59-year-old G1P1001 with a past medical history of hypertension, benign thyroid nodules, class III obesity (body mass index 35.02 kg/m2) and appendectomy with colonic resection due to intussusception as a child, presented for gynecologic consultation for a large uterine mass found on transvaginal ultrasound following a 2-month history of lower abdominal pain, vaginal bleeding, and malodorous vaginal discharge.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2377-9004/1410127


 Open Access

Liver Metastases from Gists
Gargantilla Pedro, Martin Berta and Pintor Emilio
Article Type: Case Report | First Published: July 12, 2018
Gastrointestinal Stromal Tumors (GISTs) are rare tumors of the gastrointestinal tract, with an estimated incidence of 1.5/100000/year. GISTs are nonepithelial tumors originating in the interstitial Cajal's cells (cells of the autonomic nervous system). These cells express antigens for CD 177 and/or CD 34.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2469-5793/1510080


 Open Access

Rapidly Enlarging Thyroid Mass
Gargantilla Pedro, Martin Berta and Pintor Emilio
Article Type: Short Communication | First Published: July 11, 2018
An 83-year-old man come to our observation because of a rapidly enlarging anterior neck mass at the last two weeks, dysphagia, dysphonia and neck pain. Patient didn't mention about previous irradiations on the neck either familiarity with thyroid and neoplastic diseases. He had a past medical history of diabetes mellitus type 2. Physical examination revealed one palpable formation (7 × 5 cm) over the right lower neck.

 PDF  Full Article  XML  EPub Reader  DOI:10.23937/2469-5793/1510079


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