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ClinMed International Library

For the past decade, ClinMed International Library has been at the forefront of publishing cutting-edge research in clinical medicine. Over the last 10 years, we have consistently provided a platform for publishing innovative findings and advancements in medical science.

The ClinMed International Library is a repository and an open access publisher for medical research that covers a wide range of areas in Clinical Medicine. ClinMed serves as a global platform for medical practitioners and research scholars to foster their learning and professional acumen through an extensive portfolio of research articles and publications that can be accessed without any restrictions.

Dedicated to clinical medical research, we now publish over 70 quality peer-reviewed journals making all the articles freely accessible. The manuscripts submitted to ClinMed will be processed through standard parameters and international peer review systems. This has enabled us to establish new milestones in the global research arena in terms of cogency and integrity, and to disseminate highly credible and accredited research content for researchers, scholars, and practitioners across the globe.

We ensure that all researchers and authors publishing their papers with us retain copyrights, licensed under Creative Commons Attribution License that permits the unrestricted use and re-use of the content with proper citation.


  Last Updated: April 14, 2024
Articles Search by   Keyword   |   Journal title   |   Author name   |   DOI

 Open Access DOI:10.23937/2643-4539/1710018

Alzheimer’s Disease: Beyond A Genetic Disease

Mostafa Showraki, MD, FRCPC

Article Type: Research Article | First Published: January 16, 2021

Alzheimer’s disease (AD), the most common type of dementia or neurodegenerative diseases since the beginning of the past century when it was coined by the German psychiatrist, Alois Alzheimer in 1901 holds an allusive etiology, and as a result failed most treatment and prevention strategies. Despite the common belief among the experts of AD being a genetic disease, the genetic heritability of this disease has such a wide range of 50-80% in twin and family studies that questions the totality of...

 Open Access DOI:10.23937/2378-3419/1410144

CXCR4 Antagonist AMD3100 (Plerixafor) Modulates Immune Responses in the Tumor Microenvironment

Ziyao Liu, Jingzhe Wang and Huabiao Chen

Article Type: Mini Review | First Published: January 30, 2021

AMD3100 (Plerixafor), a specific antagonist of CXCR4, is the most potent small molecule non-peptide inhibitor to CXCR4/CXCL12 axis. The chemokine receptor CXCR4 and its ligand CXCL12 (SDF-1) expressed in a variety of tumor cells play an important role in regulating tumor biological behavior. The tumor microenvironment (TME) is the environment around a tumor, comprising blood vessels, immune cells, fibroblasts, signaling molecules and the extracellular matrix which are involved in tumor growth, i...

 Open Access DOI:10.23937/2474-3674/1510114

A Rare Combination of Bilateral Obstructing Ureteral Stones, Acute Kidney Injury and Metformin-Associated Lactic Acidosis: A Case Report

RPJ Boxma, MG Vervloet and JJ Haitsma

Article Type: Case Report | First Published: February 05, 2021

Metformin associated lactic acidosis is a severe and potentially fatal condition. We here report a severe metformin-associated lactic acidosis in acute kidney injury caused by bilateral obstructing ureteral stones as an extremely rare combination of pathologies. Early treatment with bicarbonate infusion and subsequent acute haemodialysis was provided. As a result, respiratory failure and mechanical ventilation was prevented and the patient was discharged several days after the event. The patient...

 Open Access DOI:10.23937/2378-2951/1410216

Coronary Risk Factors and its Reduction by Plant-Based Diet with Emphasis on Diabetes: A Preliminary Report

Gunadhar Panigrahi, MD, FACC, FACP, DipABLM

Article Type: Research Article | First Published: February 13, 2021

Heart disease has been the leading cause of death since 1933 in the US according to the mortality records from CDC. In 2009 coronary heart disease accounted for 64% of the cardiac deaths. This is due to diet high in processed foods, high in meat, saturated fat, added sugars and other high glycemic index carbohydrate, along with sedentary lifestyle. A comprehensive survey of cardiovascular disease of the New Guinea highlanders indicated rare incidence of ischemic heart disease, and no diabetes or...

 Open Access DOI:10.23937/2378-2951/1410215

Left Ventricular Assist Devices and Their Role in Cardiogenic Shock: Literature Review and Contemporary Data

S Tzikas, AP Evangeliou, A Boulmpou, G Loufopoulos, CE Papadopoulos and V Vassilikos

Article Type: Review Article | First Published: January 30, 2021

Despite tremendous progress in the therapeutic algorithms of hemodynamically unstable patients, cardiogenic shock remains a clinical challenge with high mortality rate. Conservative management with inotropic agents remains the first-choice treatment, though it has been associated with serious adverse events and is not always adequate. Circulatory support with mechanical devices has been widely implemented in patients with cardiogenic shock during high- risk percutaneous coronary interventions or...

 Open Access DOI:10.23937/2572-4142.1510010

Is Immunohistochemistry Enough to Diagnose Xp11.2 Renal Cell Carcinoma?

Paulo Victor Zattar Ribeiro and Leonora Zonula Pope, MD

Article Type: Commentary | First Published: February 05, 2021

The correct diagnosis methods of Renal Cell Carcinoma (RCC) with Xp11.2 translocations are controversial in the current literature. Due to the possible failures of immunohistochemistry alone. So we present a possible scientific based answer with the articles yet available. Renal cell carcinoma (RCC) with Xp11.2 translocations was delineated as a distinct entity in 2004 by the World Health Organization. It was primarily associated with TFE3 gene fusion and TFE3 protein overexpression in immunohis...

 Open Access DOI:10.23937/2643-4016/1710025

Presentation and Management of an Interprosthetic Femoral Fracture between a Total Hip Arthroplasty and Revised Total Knee Arthroplasty with Distal Femoral Replacement

Mohamed Shaalan, MD, MRCS, Ashraf Dawood, MD, FRCS and William Gaine, MD, FRCS

Article Type: Case Report | First Published: February 06, 2021

An 83-year-old female sustained a right femoral interprosthetic fracture following a fall, She had a high BMI with a background history of ischaemic heart disease and type II diabetes. She was placed in a Thomas splint and underwent surgical fixation with a plate on the following trauma list. She was non-weight bearing for six weeks before partial weight bearing was commenced when callus appeared on X-ray. At six months good callus was evidenced and she was fully weight bearing. Interprosthetic ...

 Open Access DOI:10.23937/2469-5823/1510153

Review of Feasibility Studies to Ensure Conducting the Proper Nursing Intervention Research

Michiyo Oka, RN, PhD, Satsuki Takahashi, RN, MHS and Mitsuhiro Matsumoto, RN, MSN, CNS

Article Type: Commentary | First Published: January 30, 2021

When introducing a new nursing system, it is the responsibility of the introducing side to incorporate what has been confirmed. However, it is difficult to conduct a large-scale randomized controlled trial (RCT) to confirm the evidence according to the protocol. Therefore, as a nursing researcher, we would like to utilize feasibility research. In this paper, we will introduce the necessity of feasibility study, the definition of feasibility study, and the parameters for high-quality feasibility ...

 Open Access DOI:10.23937/2643-3966/1710036

Mitochondrial Dynamics and Cardiovascular Risk: An Insight at the Molecular Level

Ivan Lozada Martinez, Daniela Torres Llinás and Andres Llamas Nieves

Article Type: Commentary | First Published: February 06, 2021

Mitochondria are cellular organelles; whose function goes beyond generating adenosine triphosphate (ATP). They are part of the machinery involved in the production of substances related to iron, sulfur, and heme group, involved in lipid metabolism, calcium homeostasis, heat generation, cell signaling, stem cell pathway determination, and apoptotic processes. A vast variety of pathologies have been related to mitochondrial deficit, within these, cardiovascular diseases. Mitochondrial dysfunction ...

 Open Access DOI:10.23937/2643-3966/1710035

Homocysteine Levels and Cardiovascular Risk: Potential Predictor of Morbidity and Mortality

Ivan Lozada Martinez, Daniela Torres Llinás and Andres Llamas Nieves

Article Type: Commentary | First Published: February 06, 2021

Homocysteine is a sulfurated amino acid, deriving out of methionine from the metabolism of the methyl group. It is a non-protein substance that has been associated with the dynamics of endothelial function, platelet activation, and leukocyte interaction, with the capacity to intensify the inflammatory response in the cardiovascular system, it is therefore considered a potential cardiovascular risk marker. Some studies have evaluated homocysteine in risk groups, where it has been found that the e...

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Partnered with ICI World of Journals. Check the Index Copernicus Values of ClinMed Journals

ClinMed Journals Index Copernicus Values

Clinical Medical Reviews and Case Reports: 91.40

International Archives of Nursing and Health Care: 90.87

International Journal of Sports and Exercise Medicine: 91.84

Obstetrics and Gynaecology Cases - Reviews: 88.42

International Journal of Womens Health and Wellness: 91.79

Journal of Musculoskeletal Disorders and Treatment: 91.73

Journal of Geriatric Medicine and Gerontology: 91.55

Journal of Infectious Diseases and Epidemiology: 91.55

International Journal of Clinical Cardiology: 89.24

Journal of Dermatology Research and Therapy: 89.34



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New Issues

VOLUME 10

International Journal of Clinical Cardiology

ISSN: 2378-2951 | ICV: 89.24

VOLUME 10
VOLUME 10

Obstetrics and Gynaecology Cases - Reviews

ISSN: 2377-9004 | ICV: 88.42

VOLUME 10
VOLUME 9

Journal of Hypertension and Management

ISSN: 2474-3690 | ICV: 87.69

VOLUME 9
VOLUME 10

International Journal of Diabetes and Clinical Research

ISSN: 2377-3634 | ICV: 87.97

VOLUME 10
VOLUME 9

Journal of Infectious Diseases and Epidemiology

ISSN: 2474-3658 | ICV: 91.55

VOLUME 9

Featured Articles

Right Ventricular Mass: A Unique Approach to Tissue Diagnosis

Bistees George, MD, Marina Sharif, MD, Rishi Bolla, BS, Shaheen Muhammad, MD and Stephen Cook, MD

DOI: 10.23937/2378-2951/1410285



Cyclopia, A Rare Congenital Malformation: A Case Report in a Resource-Limited Setting in Sub-Saharan Africa

Therence N. Dingana, Carlson Sama, Nuh T. Zeh, Herbert Fonteh, Achuasah M. Tah-Atam and Gloria Ashuntantang

DOI: 10.23937/2378-3656/1410435



LigaSure for Management of Obstructed Hemivagina with Ipsilateral Renal Anomaly (OHVIRA) Syndrome

Haven Nicole Frazier, DO and Glendell de Guzman, MD

DOI: 10.23937/2377-9004/1410248


Featured Journals

Clinical Medical Reviews and Case Reports Editor-in-chief: Prof. Wei Wang

International Journal of Surgery Research and Practice Editor-in-chief: Prof. Brian Richard Davis

International Journal of Stem Cell Research & Therapy Editor-in-chief: Prof. Faris Farassati

International Journal of Clinical Cardiology Editor-in-chief: Prof. Breijo-Marquez

Journal of Genetics and Genome Research Editor-in-chief: Prof. Ming Zhan

Obstetrics and Gynaecology Cases - Reviews Editor-in-chief: Prof. Leslie Iffy

International Journal of Cancer and Clinical Research Editor-in-chief: Prof. Sulma I Mohammed

International Journal of Diabetes and Clinical Research Editor-in-chief: Prof. Masayoshi Yamaguchi

International Journal of Anesthetics and Anesthesiology Editor-in-chief: Prof. Ike Eriator

International Journal of Respiratory and Pulmonary Medicine Editor-in-chief: Prof. Shufeng Zhou

International Journal of Sports and Exercise Medicine Editor-in-chief: Prof. J David Prologo

Journal of Rheumatic Diseases and Treatment Editor-in-chief: Prof. Bruce M Rothschild

International Archives of Urology and Complications Editor-in-chief: Prof. Ajay Singla

International Journal of Psychology and Psychoanalysis Editor-in-chief: Prof. Joaquim JF Soares

Journal of Obesity and Weight-loss Medication Editor-in-chief: Prof. Timothy Koch

Trauma Cases and Reviews Editor-in-chief: Prof. William Min

Clinical Medical Image Library Editor-in-chief: Prof.

International Journal of Transplantation Research and Medicine Editor-in-chief: Prof. Lydia M Petrovic

Journal of Otolaryngology and Rhinology Editor-in-chief: Prof. John E. Nathan

Journal of Geriatric Medicine and Gerontology Editor-in-chief: Prof. Ryuichi Morishita

International Journal of Critical Care and Emergency Medicine Editor-in-chief: Prof. Yasushi Shibata

International Journal of Womens Health and Wellness Editor-in-chief: Prof. Erich Cosmi

International Journal of Brain Disorders and Treatment Editor-in-chief: Prof. Terry Lichtor

International Journal of Clinical Biostatistics and Biometrics Editor-in-chief: Prof. James Michael Hardin