ClinMed International Library

 Open Access DOI:10.23937/2469-5866/1510016

Meta-analysis of Association between Helicobacter pylori Infection and Epilepsy

Gang Yao, Ping Wang, Xiang-Dan Luo and Ting-Min Yu

Article Type: Original Article | First Published: December 06, 2016

Despite recent research focus on the association between Helicobacter pylori (H. pylori) infection and epilepsy there is no consensus about the findings. To obtain a more comprehensive estimate of the association we conducted a meta-analysis to determine the prevalence of H. pylori infection in epilepsy patients and healthy controls. PubMed, EMBASE, Cochrane Library, Web of Science, Google Scholar...

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 Open Access DOI:10.23937/2377-9004/1410100

Giant Vulvar Leiomyoma: Successful Management in a Poor Setting of a Common Neoplasm in an Uncommon Site

Bang Guy Aristide, Savom Eric Patrick, Missi Amanda Marlene, Metogo Ntsama Junie Annick and Essomba Arthur

Article Type: Case Report | First Published: December 01, 2016

In clinical practice, leiomyoma of the vulva are infrequent and rarely encountered. We report the case of a 36-year-old Cameroonian with a 10-year history of a left labia majora swelling. After evaluating history and clinical examination, a decision of excision of this tumor was taken. Intraoperatively, the mass was well circumscribed with a weight of 480 g. The cosmetic result was good. Histopath...

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 Open Access DOI:10.23937/2378-3419/3/6/1075

Cancer Antigen 125 Levels can be Used as a Tumor Marker for Monitoring Patients with Endometrial Serous Carcinoma?

MW Hegazy, Wael H Elsawy, A Tolba and M Shoukri

Article Type: Research Article | First Published: December 01, 2016

Endometrial adenocarcinoma is the most common type of uterine cancer. Endometrial cancer is classified into two subtypes (I and II), which reflect general characteristics of its clinicopathological spectrum. Uterine serous adenocarcinoma (USAC) is under Type II neoplasms which are associated with more aggressive behavior than type I tumors. While they comprise 10-20% of endometrial carcinomas, the...

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 Open Access DOI:10.23937/2378-3419/3/6/1074

Massive Arterial Bleeding after Lenvatinib Therapy for Thyroid Cancer

Koichi Suyama, DaizoMurakami, Saori Fujiwara, Takashi Takeshita, Aiko Sueta, ToukoInao, Mutsuko Yamamoto-Ibusuki, Yutaka Yamamoto, Shin-yaShiraishi and Hirotaka Iwase

Article Type: Clinical Image | First Published: November 26, 2016

A 69-year-old woman presented with hoarseness and other symptoms of laryngeal stenosis. A palpably large tumorin her neck was shown by computed tomography (CT) to expand invasively from her upper left thyroid lobe, and to involve her left common carotid artery and internal jugular vein (Figure 1 A-1). The diagnosis of papillary thyroid cancer was based on cytological evidence from fine needle aspi...

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 Open Access DOI:10.23937/2572-3286.1510018

Henoch-Schonlein Purpura after Tetanus Toxoid Vaccination: A Case Report

Wei-Yen Kong, Wan Zaharatul Ashikin Wan Abdullah, Halim Gafor, Rozita Mohd and Rizna Abdul Cader

Article Type: Case Report | First Published: December 21, 2016

We present here the first reported case of a young boy who developed classic features of HSP, i.e. palpable purpura, arthralgia, abdominal pain with bloody diarrhea and kidney involvement, following a tetanus vaccine. The diagnosis of HSP was confirmed by skin biopsy and also biopsies obtained from esophagogastroduodenoscopy and colonoscopy. He was initially treated with pulsed intravenous methylp...

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 Open Access DOI:10.23937/2572-3286.1510017

Catheter-Related Bacteraemia in Renal Replacement Therapy in Critically Ill Patients: Can We Use Femoral Access?

Sergio Castano-Avila, Javier Maynar-Moliner, Yolanda Poveda-Hernandez, Fernando Fonseca-San Miguel, Alejandro Martin-Lopez, Carlos Perez-Lejonagoitia, Noemi Legaristi-Florez, Ana Aced-Urbano, Elena Uson-Garcia and Alberto Manzano-Ramirez

Article Type: Original Article | First Published: December 14, 2016

Prospective analysis was conducted in critically ill patients with haemodialysis catheters between 25 October 2009 and 7 December 2010. We gathered data on: demographic characteristics, risk factors, extracorporeal therapy, mortality and microbiological results. CRB was detected through quantitative blood and catheter cultures. We assessed differences between aseptic and non-aseptic catheter inser...

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 Open Access DOI:10.23937/2572-3286.1510016

Surveillance of Hemodialysis Vascular Access with Temperature Biosensor Combined with Doppler-Ultrasound to Prevent Vascular Failure

Milagros Fernandez-Lucas, Fernando Caravaca-Fontan, Antonio Chinchilla, Jose-Luis Teruel, Nuria Rodriguez-Mendiola, Estefania Yerovi, Laura Blanco, Maria Delgado and Fernando Liano

Article Type: Research Article | First Published: December 12, 2016

Regular surveillance and pre-emptive correction of subclinical stenosis have been shown to be useful procedures for reducing the rate of vascular access (VA) failure. Blood flow (Qa) measurement is considered the best procedure for VA surveillance. Qa below 500 ml/min or reductions over 25% from preceding Qa measurements are predictors of VA thrombosis....

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 Open Access DOI:10.23937/2378-3419/3/6/1073

Pigmented Paget Disease of the Nipple: A Rare Breast Cancer Presentation

Santiago Sherwell-Cabello, Antonio Maffuz-Aziz, Silvia Natalia Lopez-Hernandez, Melissa Lizeth Flores-Cortes, Veronica Bautista-Pina and Sergio Rodriguez-Cuevas

Article Type: Short Review | First Published: November 26, 2016

Institutional board approval was obtained before commencement of this study. A retrospective study was conducted in all women diagnosed with breast cancer at our institution from January 2005 to December 2013. Standard immunohistochemical breast cancer panel was performed to all patients (ER, PR, Her-2 and Ki-67) and CK-7, P63 and S-100 when the pigmented variety was presented. Patients with pigme...

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 Open Access DOI:10.23937/2378-3419/3/6/1072

Colorectal Cancer Aggressiveness is Related to Fibronectin Over Expression, Driving the Activation of SDF-1:CXCR4 Axis

Sofia Gouveia-Fernandes, Tania Carvalho, Germana Domingues, Renata Bordeira-Carrico, Sergio Dias and Jacinta Serpa

Article Type: Review Article | First Published: November 19, 2016

Cancer hallmarks result from dynamical interactions between tumor cells and tumor microenvironment, including normal cells, growth factors and extracellular matrix (ECM) components. Fibronectin (FN) is a high molecular weight, multidomain glycoprotein, present as a soluble form in body fluids, such as plasma (plasma FN), and as an insoluble form in ECM (cellular FN)....

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 Open Access DOI:10.23937/2378-3419/3/6/1071

Prolonged Use of Aprepitant in Metastatic Breast Cancer and a Reduction in CA153 Tumour Marker Levels

Mark Lee, Matthew McCloskey and Stephanie Staples

Article Type: Case Report | First Published: November 16, 2016

Nausea and vomiting are common problems in patients with advanced cancer. This case report describes a patient whose refractory nausea and vomiting improved significantly with the use of Aprepitant, a highly selective neurokinin 1 receptor antagonist. This improvement led to prolonged daily administration, during which time no chemotherapy or hormone therapy was administered. CA153 tumour markers ...

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