Occupational Rhinitis and Asthma in the Textile Sector of the Central Region of Tunisia
Maoua M, Gaddour A, Rouis H, Kacem I, Guedri S, Aissa S, Ghammem M, Boughattas W, Brahem A, Kalboussi H, El Maalel O, Chatti S and Mrizak N
Article Type: Original Article | First Published: October 12, 2018
The association between occupational asthma (OA) and occupational allergic rhinitis (OAR) is often described in the literature supporting the concept of "United airways disease" based on a parallel significant reaction of the nose and lungs after challenges with occupational agents and involving several occupational, host-related and environmental factors and thus exacerbating the medical and socio-economic impact of the OR. In Tunisia, only limited studies were carried out to explore association between OA and OR....
Late - Life Depression in North Greece: Prevalence and under Detection
Konstantinos Argyropoulos, Aikaterini Saropoulou and Eleni Jelastopulu
Article Type: Research Article | First Published: October 12, 2018
Depression is the most frequent cause of emotional suffering on late life. The purpose of the present study was to estimate the prevalence of depression and to assess possible under-diagnosis of depressive symptoms in the elderly. A cross-sectional study was conducted among the members of the open day care centers for older people in the municipality of Pella, North Greece. A questionnaire was developed to collect basic demographic data, including three questions from the "European Health Interview Survey", regarding self-reported and/or by a physician diagnosed depression. Moreover, to all pa...
Factors Associating Perceived Stress and Psychological Well-being among Iranian Female Adolescents
Haleh Heizomi, Hamid Allahverdipour, Shahrzad Bazargan Hejazi, Mohammad Asghari Jafarabadi and Anaheed Shirazi
Article Type: Original Research | First Published: October 11, 2018
1) To assess the role of life satisfaction, happiness, hopefulness, and self-efficacy, on perceived stress and PWB among a sample of female high school 9th graders in Tabriz, Iran; 2) To assess direct and indirect relationships of life satisfaction, happiness, hopefulness, and self-efficacy with PWB in the sample, considering the mediator role of perceived stress under a conceptual model. This was...
Handedness Score in Unexplained Infertility, a Contribution to the Debate on Neuronal Function in Fertility
Rifat Taner Aksoy, Mehmet Cinar, Aytekin Tokmak, Enis Ozkaya, Ali Irfan Guzel and Nafiye Yilmaz
Article Type: Original Article | First Published: September 27, 2018
An estimated 15% of couples remain childless after one year of unprotected intercourse, which represents approximately 140 million people worldwide. Despite proper diagnostic work-up and as our knowledge of the events involved in normal conception is still limited, we fail to determine the cause of infertility in nearly half of these cases. Sometimes abnormalities are likely to be present, but are...
A Case of Hydroxychloroquine Induced Hypoglycaemia in a Non-Diabetic Patient
Richard De-Heer and Teresa Doherty
Article Type: Case Report | First Published: September 29, 2018
Hydroxychloroquine, originally used as an antimalarial agent, is now commonly prescribed for the treatment of rheumatic diseases such as Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE). Hydroxychloroquine associated hypoglycaemia is a rare but documented adverse effect, usually noted within the first few months of starting the medication. Here we describe the case of a patient with Rheumatoid Arthritis who developed hypoglycaemia after 7 years of treatment with a stable dose of Hydroxychloroquine....
Syphilis: A Tricky Disease that may Pose Some Diagnostic Challenges - A Case Report
Norberto Sugaya and Dante Migliari
Article Type: Case Report | First Published: September 24, 2018
This article reports a case of secondary stage syphilis involving the oral mucosa and the skin (the palms). The lesion's clinical aspects of both sites could possibly be misdiagnosed for some common inflammatory diseases, among them oral lichenoid contact lesion or drug reaction. As a standard procedure, the differential diagnosis required to rule out syphilis. The treponemal and anti-treponemal t...
The Role of Stress and Glucocorticoids in Pathogeny of Age-Related Neuropsychiatric Disorders
Viktor Ivanovitch Goudochnikov
Article Type: Review Article | First Published: September 29, 2018
An overview and commentary are presented on the role of stress and glucocorticoids in the pathogeny of age-related psychiatric and neurologic disorders, first of all depressive illness and Alzheimer's disease. The connections of these disorders with senescence-induced changes in bioregulation of hypothamo-pituitary-adrenal axis activity are discussed, focusing attention on biphasic glucocorticoid effects, gender differences, adverse effects of exogenous corticosteroids and the importance of stress and glucocorticoid effects on developing brain, as related to programming/imprinting and embeddin...
The Impact of Heat Waves on Mortality among the Elderly: A Mini Systematic Review
Antonia Kaltsatou, Glen P Kenny and Andreas D Flouris
Article Type: Review Article | First Published: September 29, 2018
The aim of this systematic review was to review the recent literature regarding the effect of heat waves on mortality in elderly adults. A systematic search of the literature, was conducted by two reviewers during March 2018, using three electronic databases (PubMed, Web of Science, and Scopus). The PRISMA guidelines were used for the quality assessment of the published studies. The literature sea...
Molecular Landscape and Clonal Evolution of Acute Mast Cell Leukemia: Case Study
Ricardo Sanchez, Maria Liz Paciello, Rosa M Ayala, Leyre Lorza, Teresa Cedena, M Pilar Martinez and Joaquin Martinez-Lopez
Article Type: Case Report | First Published: September 20, 2018
Systemic mastocytosis is a rare disorder characterized by clonal proliferation, which results in abnormally high numbers of mast cells in the skin, bone marrow, and internal organs, such as liver, spleen, or lymph nodes. Mast cell leukemia and subvariants were stratified by the World Health Organization in 2016, as a subtype of systemic mastocytosis. The World Health Organization classification of...
Why do Patients Miss their Appointments at Primary Care Clinics?
Saif Ullah, Sangeetha Rajan, Todd Liu, Ellen Demagistris, Regina Jahrstorfer, Swapna Anandan, Christina Gentile and Angad Gill
Article Type: Research Article | First Published: September 28, 2018
Missed appointments or no-shows are defined as "patients who neither kept nor canceled their scheduled appointments". Studies conducted previously in primary care settings found that the rates of missed appointments in the United States vary from 5% to 55%. We conducted a pilot study amongst the healthcare providers at Griffin Faculty Physicians (GFP) and Griffin Hospital Wellness Clinic (GHWC)......