Two major criteria or 1 major criterion and 4 minor criteria suggest a diagnosis of fat embolism syndrome.

Table 1: Two major criteria or 1 major criterion and 4 minor criteria suggest a diagnosis of fat embolism syndrome.

Major criteria	Minor criteria
Respiratory distress	Tachycardia (> 110 bpm)
Cerebral symptoms in injury patients	Fever (> 38.5 °C)
Petechial rash	Jaundice
	Renal changes
	Drop in hemoglobin
	New onset thrombocytopenia
	Elevated erythrocyte sedimentation rate
	Fat macroglobulinemia