Table 1: Comparison of HPG axis of Males and Females.

Axis

Males

Females

 

Hypothalamus

 

Kisspeptin Level [2]

+

+++

Activity [3]

GnRH pulsatile

GnRH pulsatile and GnRH surge

Feedback [4]

Negative by Testosterone

Positive by estradol

Negative by estradiol and progesterone

 

Pituitary

 

Size [5]

Smaller size

Bigger size

LH surge [2]

Absence

Exist

Feedback [6]

Negative by Testosteron

Positive by estradiol

Negative by estradiol and progesterone

 

Gonads [7,8]

 

Organ

Testis

Ovary

Location

Inside scrotum

Inside pelvic

Gonadal process

Spermatogenesis

Oogenesis

Main unit

Seminiferous tubule

Follicle

Activity

Continuous

Periodically

Duration of process

72 days

28-35 days

End product

Sperm

Oocyte

Amount of product

Numerous

1-2 oocyte release

Hormones

Testosteron

Estrogen and Progesteron

LH receptor location

Leydig Cells

Internal theca cells, Granulosa cells

Puberty sign

Nocturnal emission

Menarche (first menstruation)

Gametogenesis

Continuous

Periodical ovulation until menopause

Differences in structure and function of both sexes regarding reproductive organs (hypothalamic, pituitary and gonads [2-8]