Table 1: Comparison of HPG axis of Males and Females.
Axis |
Males |
Females |
|
Hypothalamus |
|
Kisspeptin Level [2] |
+ |
+++ |
Activity [3] |
GnRH pulsatile |
GnRH pulsatile and GnRH surge |
Feedback [4] |
Negative by Testosterone |
Positive by estradol Negative by estradiol and progesterone |
|
Pituitary |
|
Size [5] |
Smaller size |
Bigger size |
LH surge [2] |
Absence |
Exist |
Feedback [6] |
Negative by Testosteron |
Positive by estradiol Negative by estradiol and progesterone |
|
Gonads [7,8] |
|
Organ |
Testis |
Ovary |
Location |
Inside scrotum |
Inside pelvic |
Gonadal process |
Spermatogenesis |
Oogenesis |
Main unit |
Seminiferous tubule |
Follicle |
Activity |
Continuous |
Periodically |
Duration of process |
72 days |
28-35 days |
End product |
Sperm |
Oocyte |
Amount of product |
Numerous |
1-2 oocyte release |
Hormones |
Testosteron |
Estrogen and Progesteron |
LH receptor location |
Leydig Cells |
Internal theca cells, Granulosa cells |
Puberty sign |
Nocturnal emission |
Menarche (first menstruation) |
Gametogenesis |
Continuous |
Periodical ovulation until menopause |
Differences in structure and function of both sexes regarding reproductive organs (hypothalamic, pituitary and gonads [2-8]