Samples

Antioxidants

Results

References

100 female patients with nonspecific vaginitis

Vitamin C therapy

(250 mg/day/one week)

↓vaginal MDA; ↓vaginal H₂O₂; ↓mucosa epithelial cell apoptosis; ↓DNA damage ofmucosa epithelial cells; ↓caspase 3 expression; ⇑Bcl2; ↓Bax; ↓cytochrome C in mucosa epithelial cells

[47]

180 patients with bacterial vaginosis

Berberine

(as posterior vaginal fornix at 0.3 g/daily for 10 days)

⇑SOD; ⇑CAT; ↓H₂O₂; ↓caspase-3, ↓cytochrome C, ↓capase-12; ↓Bax; ⇑Bcl-2; ↓Bax/Bcl-2 ratio in vaginal discharge

[54]

35 women with vaginal

dryness

Vitamins A, C and E;

hyaluronic acid; collagen;

glucosamine sulfate;

chondroitin sulfate;

alpha-lipoic acid; methylsulfonylmethane

⇑Vaginal Health Index; ⇑Female Sexual Function ↓Index; oxidative stress

[55]

100 women with non-specific vaginal dryness

Vitamin C vaginal tablets (250 mg) once a day for a total of 20 days

⇑Bacteria disappeared; ↓Vaginal pH; ↓clue cells; ⇑lactobacilli reappeared; ⇑vaginitis improvement

[56]